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AAIC 2013:社会经济地位影响痴呆发生率

2013-07-19 MedSci Medscape today

2013年阿尔茨海默病协会国际会议上公布的一项最新研究显示,社会经济地位的差异在很大程度上能够解释痴呆发生率在种族和民族方面的差异。 研究者旧金山加州大学Kristine Yaffe博士说,“社会经济地位(SES)的差异,如收入较低,教育质量下降,可能能够解释为何与白人相比,黑人中痴呆发生率高。提高SES,尤其是教育,可能有助于降低老年痴呆的风险。” Yaffe博士指出,非裔美国老年人与白人相

2013年阿尔茨海默病协会国际会议上公布的一项最新研究显示,社会经济地位的差异在很大程度上能够解释痴呆发生率在种族和民族方面的差异。

研究者旧金山加州大学Kristine Yaffe博士说,“社会经济地位(SES)的差异,如收入较低,教育质量下降,可能能够解释为何与白人相比,黑人中痴呆发生率高。提高SES,尤其是教育,可能有助于降低老年痴呆的风险。”

Yaffe博士指出,非裔美国老年人与白人相比,其发生阿尔茨海默病和其他痴呆的风险要高两倍。SES影响老年人的认知功能。然而,“很少有研究真正把SES作为解释白人有更高的痴呆发生风险的原因。”

Yaffe博士及其研究小组评估了3075例70至79岁的黑人和白人。在12年的随访期间,575(18.7%)受试者发展为老年痴呆。在未经调整的分析中,非洲裔美国人与白人相比更容易患痴呆(21.9% vs.16.4%,风险比[HR]1.57; 95%可信区间[CI],1.33 - 1.84)。

在调整了人口学特征,存在或不存在APOE风险等位基因,合并疾病和生活方式因素后,HR减弱了,但依然存在显著统计学意义(HR,1.40,95%CI,1.17 - 1.68)。然而,将SES加入模型后,HR大大减弱,并且不具有显著统计学意义(HR,1.08,95%CI,0.86 - 1.36)。

Yaffe博士说,“这表明,SES能够解释黑人和白人发生风险的差异。其他危险因素,如合并疾病和生活方式,似乎并没有太多地影响发生风险。”社会经济学因素包括教育程度,识字率,收入,和金钱的满足感。

Yaffe博士说,这些发现是“重要的,因为较低的收入教育程度低这些SES因素在黑人中导致更高的痴呆发生率。患者的SES是不容易改善的,但是有关教育,从公共卫生以及种族人群的角度看,我认为需要考虑教育质量和程度。”

原始出处:

Economic Status May Drive Dementia Disparities.medscape.Jul 16, 2013


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