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Diabetologia:改变烹饪方式可以帮助预防糖尿病

2016-08-29 佚名 生物谷

来自美国斯奈山伊坎医学院的研究人员表示烹饪方法的简单改变或可在糖尿病预防方面产生显著影响。一项发表在国际学术期刊Diabetologia上的随机对照试验结果表明存在胰岛素抵抗情况的肥胖个体避免摄入晚期糖基化终产物(AGE)能够改善胰岛素敏感性,AGE是烹饪过程中的一种常见副产物,常见于干热烹饪以及热加工食品中。 这项研究是2014年发表在国际学术期刊PNAS上的一篇文章的后续研究,在PNAS

来自美国斯奈山伊坎医学院的研究人员表示烹饪方法的简单改变或可在糖尿病预防方面产生显著影响。一项发表在国际学术期刊Diabetologia上的随机对照试验结果表明存在胰岛素抵抗情况的肥胖个体避免摄入晚期糖基化终产物(AGE)能够改善胰岛素敏感性,AGE是烹饪过程中的一种常见副产物,常见于干热烹饪以及热加工食品中。

这项研究是2014年发表在国际学术期刊PNAS上的一篇文章的后续研究,在PNAS的文章中,斯奈山伊坎医学院的研究人员证实体内高水平的AGE会引起胰岛素抵抗增加等糖尿病前期症状,还会引起类似阿尔茨海默病的大脑变化。这项最新研究更着重于糖尿病风险的研究。

"食物中的AGE非常普遍,特别是在西方饮食中,我们的研究表明避免食用富含AGE的食物可以确实地逆转已经发生的损伤。"Dr.Vlassara这样说道。"这为糖尿病前期的临床治疗提供了一些方法,可以帮助保护特定的风险人群,避免发生糖尿病以及其他灾难性后果。"

在研究中研究人员将肥胖参与者分成两组,其中一组(Reg-AGE)食用常规饮食,其中含有较多的AGE,另外一组(L-AGE))食用AGE含量较少的食物,研究人员要求该组成员避免食用烧烤,烹炸和烘焙食物,以水煮,焖炖和蒸煮食物为主。

在实验刚开始和结束阶段分析参与者的血液和尿液样本确定胰岛素抵抗情况。在开始的时候两组表现出类似的胰岛素抵抗水平,而在研究结束阶段L-AGE组表现出显著的胰岛素抵抗改善,同时体重轻微下降,体内AGE水平也更低。而Reg-AGE组有更高的AGE水平,胰岛素抵抗标记物的表达也更强。

另一位研究人员表示,血清中升高的AGE水平可以用于存在糖尿病风险的肥胖病人的诊断和治疗,虽然体重没有显著下降,但是低AGE饮食可以帮助这些病人预防糖尿病的发生。

原始出处

Helen Vlassara, Weijing Cai, Elizabeth Tripp, Renata Pyzik, Kalle Yee, Laurie Goldberg, Laurie Tansman, Xue Chen, Venkatesh Mani, Zahi A. Fayad, Girish N. Nadkarni, Gary E. Striker, John C. He, Jaime Uribarri.Oral AGE restriction ameliorates insulin resistance in obese individuals with the metabolic syndrome: a randomised controlled trial.Diabetologia.2016


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channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=)]
    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

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  6. 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channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=)]
    2016-09-12 舒心和人

    病从口入,要管住嘴

    0

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level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118574, encodeId=b64f1185e4d2, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118575, encodeId=97931185e5bf, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=)]
    2016-09-10 1e0d5b16m97(暂无匿称)

    不错的知识点学到了很多

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1759733, encodeId=e4971e597337f, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Wed Apr 05 05:22:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637439, encodeId=9bb3163e4391b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Mar 15 07:22:00 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1820197, encodeId=fccb182019ecc, content=<a href='/topic/show?id=854a100358e6' target=_blank style='color:#2F92EE;'>#预防糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100358, encryptionId=854a100358e6, topicName=预防糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=56ea361, createdName=changhe713, createdTime=Wed May 10 20:22:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=131622, encodeId=9e0c13162202, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 20 22:10:00 CST 2016, time=2016-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647159, encodeId=a0c9164e1590d, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Dec 19 15:22:00 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=123906, encodeId=056212390649, content=病从口入,要管住嘴, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Mon Sep 12 19:24:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118577, encodeId=3d351185e762, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 10:00:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118572, encodeId=d83d1185e23a, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118574, encodeId=b64f1185e4d2, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118575, encodeId=97931185e5bf, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=)]
    2016-09-10 1e0d5b16m97(暂无匿称)

    不错的知识点学到了很多

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1759733, encodeId=e4971e597337f, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Wed Apr 05 05:22:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637439, encodeId=9bb3163e4391b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Mar 15 07:22:00 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1820197, encodeId=fccb182019ecc, content=<a href='/topic/show?id=854a100358e6' target=_blank style='color:#2F92EE;'>#预防糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100358, encryptionId=854a100358e6, topicName=预防糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=56ea361, createdName=changhe713, createdTime=Wed May 10 20:22:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=131622, encodeId=9e0c13162202, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 20 22:10:00 CST 2016, time=2016-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647159, encodeId=a0c9164e1590d, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Dec 19 15:22:00 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=123906, encodeId=056212390649, content=病从口入,要管住嘴, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Mon Sep 12 19:24:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118577, encodeId=3d351185e762, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 10:00:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118572, encodeId=d83d1185e23a, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118574, encodeId=b64f1185e4d2, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118575, encodeId=97931185e5bf, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=)]
    2016-09-10 1e0d5b16m97(暂无匿称)

    不错的知识点学到了很多

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1759733, encodeId=e4971e597337f, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Wed Apr 05 05:22:00 CST 2017, time=2017-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637439, encodeId=9bb3163e4391b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Mar 15 07:22:00 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1820197, encodeId=fccb182019ecc, content=<a href='/topic/show?id=854a100358e6' target=_blank style='color:#2F92EE;'>#预防糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100358, encryptionId=854a100358e6, topicName=预防糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=56ea361, createdName=changhe713, createdTime=Wed May 10 20:22:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=131622, encodeId=9e0c13162202, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 20 22:10:00 CST 2016, time=2016-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647159, encodeId=a0c9164e1590d, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Dec 19 15:22:00 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=123906, encodeId=056212390649, content=病从口入,要管住嘴, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Mon Sep 12 19:24:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118577, encodeId=3d351185e762, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 10:00:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118572, encodeId=d83d1185e23a, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118574, encodeId=b64f1185e4d2, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=118575, encodeId=97931185e5bf, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Sat Sep 10 09:59:00 CST 2016, time=2016-09-10, status=1, ipAttribution=)]
    2016-09-10 1e0d5b16m97(暂无匿称)

    不错的知识点学到了很多

    0

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胃泌素已被证明能促进啮齿类动物的β细胞增殖,但很大程度上其对成年人类的影响在还不清楚。 既往有报道称,质子泵抑制剂(PPI)可导致内源性血液中胃泌素升高,改善糖尿病患者的血糖控制。因此研究者进行了研究,探究PPI治疗是否与人类葡萄糖体内平衡、胰岛细胞增生或增加新的β细胞形成等有关。 研究者获取了60名既往PPI治疗和33名没有PPI治疗患者的胰腺组织。再根据糖尿病情况进行分组:没有糖尿

J Clin Endocrinol Metab:血尿酸在正常范围高限也会增加糖尿病风险

血尿酸(SUA)是体内的老旧细胞,还有食物,尤其是富含嘌呤的食物(如动物内脏、海鲜等)在体内新陈代谢过程中,其核酸氧化分解产物就有嘌呤(这种内源性的嘌呤占总嘌呤的80%)。当血尿酸在正常范围内时,会增加糖尿病风险吗?尤其是对于长得瘦看起来很健康的成年人。研究者进行了长达10年的随访队列研究,评估正常高限SUA与正常低限SUA相比,是否会增加糖尿病风险。研究纳入了469947名参与者,基线40-70

Am J Epidemiol:上海交大宁光院士发表糖尿病研究新成果

来自上海交通大学宁光院士及其团队在Am J Epidemiol杂志上发表糖尿病最新研究成果。研究研究表明,配偶之间共享一些相同的生活方式。研究结果发布在8月16日的American Journal of EPIDEMIOLOGY杂志上。 本研究以社区为基础,2011-2012年间年龄为40岁或以上的中国成人群体中,调查了糖尿病患者的配偶是否具有更高的糖尿病和心血管代谢疾病发病率。在这项研

J Intern Med:卒中入院前使用SSRI会增加死亡率

糖尿病患者的卒中风险增加,并且预后差。此外,糖尿病患者的抑郁症风险增加,因此可能使用选择性5-羟色胺再摄取抑制剂(SSRIs)。我们的目的是探究糖尿病卒中入院前使用SSRI,是否增加卒中死亡率。使用基于人口的医疗数据库确定丹麦2004-2012年的首次卒中相关住院糖尿病患者,获取了随后死亡率数据(n = 12 620)。基于患者的处方信息,SSRI使用分为当前使用(新使用或长期使用)、先前使用或不

2016临床实践指南——成人2型糖尿病患者的预防,早期识别,诊断,管理以及随访发布

本文主要内容包括了2型糖尿病的预防,早期识别,诊断,管理以及随访等内容。全文获取:下载地址:指南下载 (需要扣积分2分, 梅斯医学APP免积分下载)

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