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medRxiv: 英国团队建立CoVID-19传播空间模型,估计病毒在英格兰和威尔士的早期传播趋势和峰值时间

2020-03-22 公共卫生学术热点追踪 公共卫生学术热点追踪

2月14日,medRxiv预印本上发表了一篇来自英国埃克塞特大学、布里斯托尔大学、华威大学研究团队的题为“Aspatial model of CoVID-19 transmission i

2月14日,medRxiv预印本上发表了一篇来自英国埃克塞特大学、布里斯托尔大学、华威大学研究团队的题为“Aspatial model of CoVID-19 transmission in England and Wales: early spread andpeak timing”的文章,使用现有的全国规模集合种群(metapopulation)模型来评估COVID-19在英国和威尔士的传播,文章使用2011年的人口普查数据来获取人口规模和人口流动情况,以及使用中国当前疫情的参数估计。

研究结果预测,在没有对照和生物参数保持不变的前提下,在英格兰和威尔士的人与人之间传播开始后126至147天(~4个月)内,CoVID-19的爆发将达到高峰。因此,如果从2月份开始出现人与人之间的传播并持续下去,文章预测英格兰和威尔士的疫情高峰将出现在6月份。起始时间对峰时影响最小,模型随机性会使峰时有10天的变动空间。结合实际参数的不确定性,峰值时间估计在人与人之间传播出现后的78天到241天之间。传染率的季节性变化对流行高峰出现的时间和规模、以及总发病率都有很大的影响。

在没有控制措施的情况下,文章初步估计了CoVID-19在英格兰和威尔士的潜在传播进程。这些结果可以通过改进流行病学参数估计来修正,并可用于控制措施调查和成本效益分析。传播率的季节性变化可能会将高峰时间推迟到冬季,这将对英格兰和威尔士的医疗能力和措施规划产生重要影响。

原始出处:
Leon Danon, et al. A spatial model of CoVID-19 transmission in England and Wales: early spread and peak timing. medRxiv. doi: https://doi.org/10.1101/2020.02.12.20022566

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    2020-03-27 thm112988

    0

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    2020-03-23 CHANGE

    梅斯里提供了很多疾病的模型计算公式,赞一个!

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