Baidu
map

Breast Cancer Research:女儿患乳腺癌的风险受父亲进食的脂肪种类影响

2016-07-27 MedSci MedSci原创

圣保罗大学的Thomas Ong博士发现,雄性小鼠若进食大量植物油食物,则雌性后代患乳腺癌的风险降低。研究结果发表在Breast Cancer Research。研究人员指出,如果他们的结果通过人体试验得以证实,那么纠正父亲饮食观念可能是一种降低女性患乳腺癌发病率的新的干预措施。 在美国,乳腺癌是女性最常见的第二大癌症,约1/8的女性会罹患该病。女性患乳腺癌的风险受到很多因素的影响,如疾病家族史和

圣保罗大学的Thomas Ong博士发现,雄性小鼠若进食大量植物油食物,则雌性后代患乳腺癌的风险降低。研究结果发表在Breast Cancer Research。研究人员指出如果他们的结果通过人体试验得以证实那么纠正父亲饮食观念可能是一种降低女性后代乳腺癌发病率的新的干预措施。

在美国,乳腺癌是女性最常见的第二大癌症约1/8的女性会罹患该病。女性患乳腺癌的风险受很多因素的影响如疾病家族史和遗传性基因突变等。越来越多的研究人员发现父亲的身体健康状况和生活方式可能对后代患乳腺癌风险有所影响。 

Ong博士和同事通过进行研究发现,父亲的饮食方式可能影响女性后代患乳腺癌的风险。

研究人员将60只雄性老鼠平均分为2组,实验组小鼠饲喂猪油或玉米油等高脂肪饮食脂肪含量约占60%对照组饲喂的饮食中脂肪含量约为16%。研究人员指出玉米油富含ω- 6系列多不饱和脂肪酸而猪油则含有较高含量的饱和脂肪。接下来研究人员令雄性小鼠与饲喂正常食物的雌性小鼠交配。小鼠的雌性后代也吃普通食物50天成熟后研究人员启动其中乳腺肿瘤的生长程序。研究人员评估雌性小鼠后代的肿瘤患病率、肿瘤出现时间、数量、体积等信息并进行分析。 

相比对照组的雌性小鼠后代而言,进食玉米油的雄性小鼠的后代中,雌性小鼠体内的肿瘤细胞生长缓慢,肿瘤细胞更少,也就是说雌性小鼠需要更长的时间启动肿瘤生长。 

因此,研究人员指出,父亲进食脂肪种类可影响女儿患乳腺癌的风险,多摄入植物油食物可降低女儿患乳腺癌的风险。研究人员表示仍需进行更进一步的研究以探究父亲的进食种类对女儿乳腺组织发育的影响。

原始出处:

[1] Breast cancer risk may be influenced by type of fat dad eats. MNT.2016 Jul 26.

[2] Thomas Ong,et al. Paternal programming of breast cancer risk in daughters in a rat model: opposing effects of animal- and plant-based high-fat diets. Breast Cancer Research. 2016 July 25.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1710891, encodeId=9f401e1089193, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Aug 24 03:56:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119521, encodeId=33451195219c, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 16:58:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98246, encodeId=5d4c98246b0, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160812/IMG57AD9E92D552A2087.jpg, createdBy=a35f100635, createdName=sophiahuang, createdTime=Sat Aug 13 17:50:00 CST 2016, time=2016-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351086, encodeId=4dbb135108686, content=<a href='/topic/show?id=12e43e1263' target=_blank style='color:#2F92EE;'>#Breast#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3712, encryptionId=12e43e1263, topicName=Breast)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557746, encodeId=475b155e7467a, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585114, encodeId=20d9158511412, content=<a href='/topic/show?id=625c9440e39' target=_blank style='color:#2F92EE;'>#进食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94407, encryptionId=625c9440e39, topicName=进食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94cc17130334, createdName=gj0737, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1710891, encodeId=9f401e1089193, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Aug 24 03:56:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119521, encodeId=33451195219c, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 16:58:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98246, encodeId=5d4c98246b0, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160812/IMG57AD9E92D552A2087.jpg, createdBy=a35f100635, createdName=sophiahuang, createdTime=Sat Aug 13 17:50:00 CST 2016, time=2016-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351086, encodeId=4dbb135108686, content=<a href='/topic/show?id=12e43e1263' target=_blank style='color:#2F92EE;'>#Breast#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3712, encryptionId=12e43e1263, topicName=Breast)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557746, encodeId=475b155e7467a, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585114, encodeId=20d9158511412, content=<a href='/topic/show?id=625c9440e39' target=_blank style='color:#2F92EE;'>#进食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94407, encryptionId=625c9440e39, topicName=进食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94cc17130334, createdName=gj0737, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=)]
    2016-09-10 1e10c84am36(暂无匿称)

    好文章,百姓也能从中学到好多医学知识

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1710891, encodeId=9f401e1089193, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Aug 24 03:56:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119521, encodeId=33451195219c, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 16:58:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98246, encodeId=5d4c98246b0, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160812/IMG57AD9E92D552A2087.jpg, createdBy=a35f100635, createdName=sophiahuang, createdTime=Sat Aug 13 17:50:00 CST 2016, time=2016-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351086, encodeId=4dbb135108686, content=<a href='/topic/show?id=12e43e1263' target=_blank style='color:#2F92EE;'>#Breast#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3712, encryptionId=12e43e1263, topicName=Breast)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557746, encodeId=475b155e7467a, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585114, encodeId=20d9158511412, content=<a href='/topic/show?id=625c9440e39' target=_blank style='color:#2F92EE;'>#进食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94407, encryptionId=625c9440e39, topicName=进食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94cc17130334, createdName=gj0737, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=)]
    2016-08-13 sophiahuang

    有趣

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1710891, encodeId=9f401e1089193, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Aug 24 03:56:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119521, encodeId=33451195219c, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 16:58:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98246, encodeId=5d4c98246b0, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160812/IMG57AD9E92D552A2087.jpg, createdBy=a35f100635, createdName=sophiahuang, createdTime=Sat Aug 13 17:50:00 CST 2016, time=2016-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351086, encodeId=4dbb135108686, content=<a href='/topic/show?id=12e43e1263' target=_blank style='color:#2F92EE;'>#Breast#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3712, encryptionId=12e43e1263, topicName=Breast)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557746, encodeId=475b155e7467a, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585114, encodeId=20d9158511412, content=<a href='/topic/show?id=625c9440e39' target=_blank style='color:#2F92EE;'>#进食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94407, encryptionId=625c9440e39, topicName=进食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94cc17130334, createdName=gj0737, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=)]
    2016-07-29 zhaojie88
  5. [GetPortalCommentsPageByObjectIdResponse(id=1710891, encodeId=9f401e1089193, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Aug 24 03:56:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119521, encodeId=33451195219c, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 16:58:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98246, encodeId=5d4c98246b0, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160812/IMG57AD9E92D552A2087.jpg, createdBy=a35f100635, createdName=sophiahuang, createdTime=Sat Aug 13 17:50:00 CST 2016, time=2016-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351086, encodeId=4dbb135108686, content=<a href='/topic/show?id=12e43e1263' target=_blank style='color:#2F92EE;'>#Breast#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3712, encryptionId=12e43e1263, topicName=Breast)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557746, encodeId=475b155e7467a, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585114, encodeId=20d9158511412, content=<a href='/topic/show?id=625c9440e39' target=_blank style='color:#2F92EE;'>#进食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94407, encryptionId=625c9440e39, topicName=进食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94cc17130334, createdName=gj0737, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=)]
    2016-07-29 yangshch
  6. [GetPortalCommentsPageByObjectIdResponse(id=1710891, encodeId=9f401e1089193, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Aug 24 03:56:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119521, encodeId=33451195219c, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 16:58:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98246, encodeId=5d4c98246b0, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160812/IMG57AD9E92D552A2087.jpg, createdBy=a35f100635, createdName=sophiahuang, createdTime=Sat Aug 13 17:50:00 CST 2016, time=2016-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351086, encodeId=4dbb135108686, content=<a href='/topic/show?id=12e43e1263' target=_blank style='color:#2F92EE;'>#Breast#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3712, encryptionId=12e43e1263, topicName=Breast)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557746, encodeId=475b155e7467a, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585114, encodeId=20d9158511412, content=<a href='/topic/show?id=625c9440e39' target=_blank style='color:#2F92EE;'>#进食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94407, encryptionId=625c9440e39, topicName=进食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94cc17130334, createdName=gj0737, createdTime=Fri Jul 29 11:56:00 CST 2016, time=2016-07-29, status=1, ipAttribution=)]
    2016-07-29 gj0737

相关资讯

Breast Cancer Res:长期使用钙离子通道阻滞剂并不会增加乳腺癌的发病风险

近日,一项病例对照研究发现长期使用钙通道阻断药物与乳腺癌的发病风险增加两倍有关。若前瞻性研究证实钙离子通道阻断剂可增加乳腺癌的发病风险,那么这将大大影响高血压的治疗。本研究旨在通过与不使用钙通道阻滞剂的女性相比,确定使用钙离子通道阻滞剂治疗10年及以上的女性乳腺癌的发病风险是否会增加。研究纳入了35-74岁之间的女性,纳入标准要求参与者有一个乳腺癌的姐妹,但是参与者本身并没有诊断为乳腺癌。本研究共

乳腺癌新药3期临床疗效显著,已向FDA提交新药申请

今天,总部位于美国洛杉矶的生物技术公司 Puma Biotechnology 宣布了最新补充的积极3期临床试验(ExteNET trial)结果,在该项研究中使用其在研新药来那替尼(neratinib)延长性辅助治疗早期HER2阳性反应的乳腺癌患者。同时,基于这些良好的3期(ExteNET)结果,Puma 向美国FDA提交了一份有关来那替尼的新药申请(NDA)

Breast Cancer Res Treat:内分泌治疗和乳腺癌患者认知间联系

背景:内分泌为基础的治疗是绝经后乳腺癌女性患者的主要治疗方法,但有研究认为,该治疗会对患者的认知产生不利效果。 目的和方法:因此研究者对已发表文章进行了系统回顾,评估内分泌为基础乳腺癌治疗方式与患者认知间的关系,以及年龄对两者关系是否有影响。结果:研究者通过检索相关数据库,共纳入了21项研究(n = 2398),其中10项为短期研究(持续时间≤2年),11项为长期研究(持续时间>2年)。9项(43

Breast Cancer Res:辟谣!大型前瞻性研究发现女性心理压力并不会增加乳腺癌的发病风险

女性诊断为乳腺癌后通常将其病因归咎于心理压力,但是支持此看法的研究甚少。本研究旨在探究常有心理压力及不良生活事件是否会影响日后乳腺癌的发生风险。采用前瞻性研究共纳入了英国10.6万名女性,均匀随访6.1年,其间1783名女性发生乳腺癌。使用Cox比例风险模型评估相对风险来作为风险比。结果并未发现乳腺癌发病风险与心理压力的频率相关。随访前5年期间,近亲死亡的乳腺癌危险降低13%(RR:0.87,95

Breast Cancer Res Treat:中国乳腺癌女性BRCA1/2突变研究

目的:探究中国乳腺癌女性患者的BRCA1/2癌胚系突变的发生率及其特征研。方法:纳入5931名中国乳腺癌女性患者,检测患者的BRCA1/2突变情况。其中,543例家族性乳腺癌、1033例早发性疾病(≤40岁)无乳腺癌家族史、4355例散发性乳腺癌(>40岁)。结果:总的来说,在这5931例患者的队列中,232例患者(3.9%)携带BRCA1或BRCA2基因突变(110例BRCA1和122例BRCA

Breast Cancer Res Treat:乳腺癌患者将受益于抗阻运动训练

目的:探究抗阻运动训练(RET)和有氧运动训练(AET) 对接受辅助化疗的乳腺癌(BC)患者的肌肉减少症、年龄相关肌肉力量损失、相关的生活质量(QoL)变化的影响。方法:化疗期间参与者被随机分为常规护理(UC)(n = 70)、AET(n = 64)和RET (n = 66)。测量患者肌肉减少症(骨骼肌肉指数 SMI)、年龄相关肌肉力量损失(上肢(UE) 和下肢(LE)肌肉功能障碍(MD))、相关

Baidu
map
Baidu
map
Baidu
map