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J Clin Endocrinol Metab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险

2016-12-19 MedSci MedSci原创

近日,来自韩国高丽大学九老医院的一项新的研究发现表明,胰岛素抵抗的非腹型肥胖患者重度牙周炎的发生风险较高。胰岛素抵抗可被作为腹部肥胖的正常体重人群牙周病发生的独立危险因素。该研究中,研究人员推测即使是正常体重的个体,存在胰岛素抵抗也会加重牙周炎的严重程度。研究人员探究了糖尿病、胰岛素抵抗和严重牙周炎之间的关系.。研究共纳入29235名参与者,其中5690名参与者社区牙周指数(CPI)为3或4(牙周

近日,来自韩国高丽大学九老医院的一项新的研究发现表明,胰岛素抵抗的非腹型肥胖患者重度牙周炎的发生风险较高。胰岛素抵抗可被作为腹部肥胖的正常体重人群牙周病发生的独立危险因素。

该研究中,研究人员推测即使是正常体重的个体,存在胰岛素抵抗也会加重牙周炎的严重程度。研究人员探究了糖尿病、胰岛素抵抗和严重牙周炎之间的关系.。

研究共纳入29235名参与者,其中5690名参与者社区牙周指数(CPI)为3或4(牙周病)年龄≥30岁。研究所用数据来源于2008-2010年韩国国家健康和营养调查研究。

结果,与2型糖尿病患者相比,糖耐量正常或空腹血糖受损的患者更易患重度牙周炎(CPI 4)(P<0.001)。严重牙周炎的患者腹型肥胖、血清甘油三酯和胰岛素抵抗的几率更高(P值分别为0.12,<0.001和0.003)。校正潜在的混杂因素后(趋势P=0. 003),从正常糖耐量、空腹血糖受损(OR= 1.32;95%置信区间,1.06-1.64)到2型糖尿病(OR=1.5;95% CI,1.11-2.02),重度牙周炎患病率的比值比(ORs)显著增加。非糖尿病人群中,随着胰岛素抵抗的增加,重度牙周炎的患病率显著升高(趋势P = 0.04)。此外,与胰岛素敏感的正常腰围个体相比,胰岛素抵抗的正常腰围个体重度牙周炎的发生几率显著升高(OR= 1.47;95% CI,1.16-1.87)。

原始出处:

Song IS, Han K. et al., Severe Periodontitis Is Associated with Insulin Resistance in Non-abdominal Obese Adults. J Clin Endocrinol Metab. 2016 Nov;101(11):4251-4259.


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    2017-07-11 baoya
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    2017-03-14 chg121
  4. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Thu Dec 22 08:01:18 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450495, encodeId=f2351450495fc, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1528079, encodeId=250615280e9d1, content=<a href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
    2017-11-17 guojianrong
  5. 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href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
    2017-02-09 一闲
  6. 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href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
    2016-12-22 cqykthl

    人类疾病发生发展再逐渐被解密

    0

  7. 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href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1749674, encodeId=8fb61e49674d5, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue Jul 11 22:35:00 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1934335, encodeId=0bde193433537, content=<a href='/topic/show?id=5d1195823b1' target=_blank style='color:#2F92EE;'>#重度牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95823, encryptionId=5d1195823b1, topicName=重度牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Thu Dec 22 08:01:18 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450495, encodeId=f2351450495fc, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1528079, encodeId=250615280e9d1, content=<a href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
    2016-12-21 nymo
  9. [GetPortalCommentsPageByObjectIdResponse(id=1749674, encodeId=8fb61e49674d5, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Tue Jul 11 22:35:00 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1934335, encodeId=0bde193433537, content=<a href='/topic/show?id=5d1195823b1' target=_blank style='color:#2F92EE;'>#重度牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95823, encryptionId=5d1195823b1, topicName=重度牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, 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href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
    2016-12-21 1e159d62m78(暂无匿称)

    JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。

    0

  10. 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encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Nov 17 14:35:00 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895983, encodeId=46221895983f2, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Feb 09 18:35:00 CST 2017, time=2017-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164805, encodeId=6286164805ba, content=人类疾病发生发展再逐渐被解密, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Thu Dec 22 08:01:18 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450495, encodeId=f2351450495fc, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1528079, encodeId=250615280e9d1, content=<a href='/topic/show?id=407985544d9' target=_blank style='color:#2F92EE;'>#腹型肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85544, encryptionId=407985544d9, topicName=腹型肥胖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76c911894457, createdName=nymo, createdTime=Wed Dec 21 14:35:00 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164556, encodeId=a72c1645563d, content=JClinEndocrinolMetab:腹型肥胖者胰岛素抵抗可增加重度牙周炎的发生风险。简而言之。, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161219/IMG5857911F80DEF4351.jpg, createdBy=75981969729, createdName=1e159d62m78(暂无匿称), createdTime=Wed Dec 21 07:07:55 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164336, encodeId=c7a116433612, content=就那么点内容反反复复啰里啰嗦就是一句话。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Tue Dec 20 10:18:20 CST 2016, time=2016-12-20, status=1, ipAttribution=)]
    2016-12-20 医张生

    就那么点内容反反复复啰里啰嗦就是一句话。

    0

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