Fertil Steril：IVF妊娠结局下降与BMI的关系

2015-12-15 candy 译 MedSci原创

目的：研究BMI对新鲜自体循环IVF结局的影响。设计：回顾性队列研究。设备：无。对象：共纳入来自辅助生殖技术学会从2008年-2010年的239127例鲜胚移植的患者，根据世界卫生组织的体重指数分层。正常BMI（18.5-24.9 kg/m2）被纳入到参照组（REF）。亚组研究单纯性多囊卵巢综合症的周期。干预：无主要测量结果：着床率、临床妊娠率、妊娠率、妊娠后流产率、生存率。结果：成功率和调整95

目的：研究BMI对新鲜自体循环IVF结局的影响

设计：回顾性队列研究

设备：无

对象：共纳入来自辅助生殖技术学会从2008年-2010年的239127例鲜胚移植的患者，根据世界卫生组织的体重指数分层。正常BMI（18.5-24.9 kg/m2）被纳入到参照组（REF）。亚组研究单纯性多囊卵巢综合症的周期。

干预：无

主要测量结果：着床率、临床妊娠率、妊娠率、妊娠后流产率、生存率。

结果：成功率和调整95%CI的OR显示：低和正常BMI组中妊娠结局趋向良好，而随着BMI指数的增加，妊娠结局趋向恶化。另外肥胖对PCOS患者和男性因素不孕的IVF结局呈负相关，虽然这一点并未达到统计学意义。

结论：鲜胚自体循环的成功率（包括那些专门为PCOS和男性因素不孕者）在低和正常BMI指数的人群中显得最高。而且，在高BMI指数的人群中，显示有一个渐进的和有明显统计学意义的结论，即BMI越高，结局越糟糕。今后需要探索BMI影响IVF成功率的原因，并且扩展到针对其他患者群体的研究。

原始出处：

Provost, M. P., et al. (2015).Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008-2010 Society for Assisted Reproductive Technology registry.Fertil Steril.

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婆婆啪啪啪

128 0
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2016-03-24 三毛坨

i快快快

104 0
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2016-03-24 三毛坨

哈哈哈哈

100 0
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2016-03-24 三毛坨

噼噼啪啪

68 0
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2016-03-24 三毛坨

婆婆啪啪啪

100 0
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2016-03-24 三毛坨

婆婆啪啪啪

146 0
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2016-03-24 三毛坨

噼噼啪啪

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