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Lancet HIV:HIV全球负担研究

2016-07-22 Mechront 译 MedSci原创

根据全球疾病负担2015研究数据,自2005以来,每年死于艾滋病病毒的案例从180万下降到120万;然而,同一时期每年的新感染率却大约有260万例。这些数据近期公布在南非德班举行的AIDS 2016上,同时Lancet HIV也予以了刊登。来自华盛顿大学的Christopher J.L. Murray博士说:“如果这种居高不下的新感染的趋势持续下去,联合国可持续发展目标在不到15年时间里终结艾滋病

根据全球疾病负担2015研究数据,自2005以来,每年死于艾滋病病毒的案例从180万下降到120万;然而,同一时期每年的新感染率却大约有260万例。

这些数据近期公布在南非德班举行的AIDS 2016上,同时Lancet HIV也予以了刊登。来自华盛顿大学的Christopher J.L. Murray博士说:“如果这种居高不下的新感染的趋势持续下去,联合国可持续发展目标在不到15年时间里终结艾滋病,将面临重大挑战。”

IHME全球健康助理教授和华盛顿大学的Haidong Wang博士为了确定全球艾滋病毒负担对数据进行了分析。

据报道,全球艾滋病发病率高峰在1997年,新感染案例为330万(95% UI, 3.1-3.4);到2005年该数据下降到260万例每年(范围250万-280万),但自该以来一直保持这样的速度 。此后,2015年,HIV/AIDS幸存者数据增加到3880万(95% UI, 37.6-40.4);每年艾滋病死亡人数从2005年的180万(95% UI, 1.7-1.9)下降到2015年的120万(95% UI, 1.1-1.3)。

截止2015年ART治疗人数也从2005年开始增加,男性(6.4% to 38.6%) 和女性(3.3% to 42.4%)均增加,但是女性相比男性,死亡年龄更小。虽然大多数国家的死亡率和发病率下降,包括HIV/AIDS最大负担的国家,但是菲律宾和印度尼西亚的流行率在增加。

总体而言,这些估计表明,近年来,对艾滋病毒死亡率是“巨大的进步”,但在减少新感染方面,进展甚微,研究人员写道。

原始出处:

Wang H, et al. Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015.Lancet HIV. 2016;doi:10.1016/S2352-3018(16)30087-X.

Global HIV deaths declining, but incidence rates remain stagnant.Healio.July 22, 2016

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    2016-10-08 1e10c84am36(暂无匿称)

    文章很棒,继续学习

    0

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    2016-08-10 howi
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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

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    2016-08-06 oo902

    全球负担

    0

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    2016-07-23 doctorJiangchao

    值得学习

    0

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    2016-07-23 doctorJiangchao

    继续关注

    0

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    2016-07-23 oo902

    学习了,很好的文章

    0

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    2016-07-23 WEIXINa82df6bc

    防治负担很重

    0

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在一项新的研究中,来自加拿大蒙特利尔大学医院研究中心的研究人员鉴定出在抗逆转病毒治疗(antiretroviral therapy, ART)期间,为HIV病毒提供“安全场所”的细胞。相关研究结果于2016年7月14日发表在PLoS Pathogens期刊上,论文标题为“CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV

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