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JAMA Network Open:有意思的研究——用吸管治疗打嗝

2021-07-04 DY MedSci原创

新设备有助于控制膈肌收缩,防止肌肉痉挛引发打嗝。

当横膈膜(位于肺部下方的大块肌肉)突然痉挛,导致喉咙收缩并关闭会厌(吞咽时覆盖气管以防止食物和液体进入气道的小皮瓣)时,就会发生打嗝。

对大多数人来说,在公共场所打嗝既恼人又尴尬。但对某些人来说,打嗝也会极大地影响他们的生活质量,包括癌症患者和脑部受伤的人。

缓解一过性打嗝的家庭疗法,如屏住呼吸、在纸袋中循环呼吸、从杯子的远端喝水等,都存在着说明不明确、性能不一致和效果差等问题。我们需要一种简单而有效的方法来阻止打嗝。

6月18日,发表在《美国医学会杂志》网络版( JAMA Network Open)上的一项研究为我们找到了一种缓解打嗝的方法。

doi:10.1001/jamanetworkopen.2021.13933

该研究对249名研究参与者使用一种名为“强制吸气和吞咽工具(FISST)”的新打嗝干预措施。结果显示,有90.8%的人对该措施表现积极态度,认为与对着纸袋呼吸或被朋友吓到等家庭补救措施相比,这种方法更能有效缓解打嗝。

FISST是一个带有进水阀的硬质饮水管,需看起来像一根粗粗的奶昔吸管,但底部只有一个很小的开口,所以使用者必须用力吸吮才能喝水。而在吸吮过程中,强大的吸力迫使隔膜收缩,防止其痉挛,并迫使会厌关闭,最终或起到防打嗝效果。FISST已获得专利,品牌为“HiccAway”。

该工具顶部有吹嘴,中间有主体,下端有可调节压力值的帽。使用方法:取一个装满水的杯子,将下端浸入水中。用吸嘴用力吸,然后吞下水;吸水时会遇到阻力。打嗝通常会在1到2次尝试后立即停止

在这项横断面研究中,志愿者通过2020年的在线活动获得FISST,并接受了4个月的前瞻性随访。研究遵循《加强流行病学观察性研究报告》(STROBE)。

在全球范围内,有674名打嗝参与者自愿接受使用该设备,290名参与者(43%)提供了参与研究的书面同意,并通过在线问卷提供了对FISST的主观评价。

在最终符合标准的249人中,大多数参与者(69.5%)报告每月至少打嗝一次,大多数(65.9%)打嗝持续时间不超过2小时。FISST在近92%的病例中有效阻止了打嗝,在所有人口统计学特征、打嗝频率和打嗝持续时间方面,FISST与家庭疗法相比都得到了良好的评价。在接受调查问卷的参与者中,FISST的平均主观有效性评分为4.58(0.90);203名参与者中的183名(90.1%)认为,与家庭疗法相比,FISST评价良好(4或5)。平均满意度为4.57(1.61),249名参与者中有226名(90.8%)认为FISST比家庭疗法更可行(4或5)。没有不良反应的报告。

与家庭疗法相比,参与者FISST的评价

总体来看,这些结果支持使用FISST作为停止短暂性打嗝的一种选择。就像前文所述,以往许多家庭疗法包括物理操作等,旨在刺激膈肌收缩和/或会厌的关闭。这些方法缺乏明确的、标准化的说明,执行起来可能很麻烦,而且对其有效性的科学研究很少。药物和其他疗法虽然有不同程度的成功,但不良反应却是一个令人关注的问题。

而该研究证实,FISST是一个易于使用的工具,可以缓解短暂的打嗝,且该设备与家庭补救措施相比具有更好的效果,它可以立即起作用,效果能保持几个小时,在未来可能具有广泛适用性。当然,研究人员还需要在随机的临床试验中评估FISST的疗效。

原始出处:

Evaluation of the Forced Inspiratory Suction and Swallow Tool to Stop Hiccups.JAMA Netw Open. 2021;4(6):e2113933. doi:10.1001/jamanetworkopen.2021.13933

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    2021-09-17 canlab
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    2022-02-26 feather89
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    2021-10-06 hyf039
  4. [GetPortalCommentsPageByObjectIdResponse(id=1734394, encodeId=c31f1e3439471, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Sep 17 08:08:14 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729018, encodeId=2d8f1e2901838, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Feb 26 12:08:14 CST 2022, time=2022-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718728, encodeId=b2511e18728ba, content=<a href='/topic/show?id=b5e85463053' target=_blank style='color:#2F92EE;'>#打嗝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54630, encryptionId=b5e85463053, topicName=打嗝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8da32602155, createdName=hyf039, createdTime=Wed Oct 06 22:08:14 CST 2021, time=2021-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996529, encodeId=6aa09965294e, content=好办法!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/f645756269ba45cba20b74d86f6e4d05/b0a88b1bdfc44cb79e79818ce296dbb9.jpg, createdBy=c2c55519856, createdName=wml_guyue, createdTime=Mon Jul 05 21:00:02 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996350, encodeId=939a9963508d, content=希望有效,临床好评, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Mon Jul 05 10:47:28 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996330, encodeId=e66699633068, content=真是解决了公共场合打嗝的尴尬, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Mon Jul 05 09:27:26 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996309, encodeId=f7e29963094c, content=学到新招了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ec235476032, createdName=ms1000001439107490, createdTime=Mon Jul 05 08:17:10 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036723, encodeId=12ee1036e2366, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Jul 05 01:08:14 CST 2021, time=2021-07-05, status=1, ipAttribution=)]
    2021-07-05 wml_guyue

    好办法!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1734394, encodeId=c31f1e3439471, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Sep 17 08:08:14 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729018, encodeId=2d8f1e2901838, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Feb 26 12:08:14 CST 2022, time=2022-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718728, encodeId=b2511e18728ba, content=<a href='/topic/show?id=b5e85463053' target=_blank style='color:#2F92EE;'>#打嗝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54630, encryptionId=b5e85463053, topicName=打嗝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8da32602155, createdName=hyf039, createdTime=Wed Oct 06 22:08:14 CST 2021, time=2021-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996529, encodeId=6aa09965294e, content=好办法!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/f645756269ba45cba20b74d86f6e4d05/b0a88b1bdfc44cb79e79818ce296dbb9.jpg, createdBy=c2c55519856, createdName=wml_guyue, createdTime=Mon Jul 05 21:00:02 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996350, encodeId=939a9963508d, content=希望有效,临床好评, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Mon Jul 05 10:47:28 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996330, encodeId=e66699633068, content=真是解决了公共场合打嗝的尴尬, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Mon Jul 05 09:27:26 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996309, encodeId=f7e29963094c, content=学到新招了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ec235476032, createdName=ms1000001439107490, createdTime=Mon Jul 05 08:17:10 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036723, encodeId=12ee1036e2366, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Jul 05 01:08:14 CST 2021, time=2021-07-05, status=1, ipAttribution=)]
    2021-07-05 言西早

    希望有效,临床好评

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1734394, encodeId=c31f1e3439471, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Sep 17 08:08:14 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729018, encodeId=2d8f1e2901838, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Feb 26 12:08:14 CST 2022, time=2022-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718728, encodeId=b2511e18728ba, content=<a href='/topic/show?id=b5e85463053' target=_blank style='color:#2F92EE;'>#打嗝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54630, encryptionId=b5e85463053, topicName=打嗝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8da32602155, createdName=hyf039, createdTime=Wed Oct 06 22:08:14 CST 2021, time=2021-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996529, encodeId=6aa09965294e, content=好办法!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/f645756269ba45cba20b74d86f6e4d05/b0a88b1bdfc44cb79e79818ce296dbb9.jpg, createdBy=c2c55519856, createdName=wml_guyue, createdTime=Mon Jul 05 21:00:02 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996350, encodeId=939a9963508d, content=希望有效,临床好评, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Mon Jul 05 10:47:28 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996330, encodeId=e66699633068, content=真是解决了公共场合打嗝的尴尬, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Mon Jul 05 09:27:26 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996309, encodeId=f7e29963094c, content=学到新招了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ec235476032, createdName=ms1000001439107490, createdTime=Mon Jul 05 08:17:10 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036723, encodeId=12ee1036e2366, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Jul 05 01:08:14 CST 2021, time=2021-07-05, status=1, ipAttribution=)]
    2021-07-05 乙娆

    真是解决了公共场合打嗝的尴尬

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1734394, encodeId=c31f1e3439471, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Sep 17 08:08:14 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729018, encodeId=2d8f1e2901838, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Feb 26 12:08:14 CST 2022, time=2022-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718728, encodeId=b2511e18728ba, content=<a href='/topic/show?id=b5e85463053' target=_blank style='color:#2F92EE;'>#打嗝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54630, encryptionId=b5e85463053, topicName=打嗝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8da32602155, createdName=hyf039, createdTime=Wed Oct 06 22:08:14 CST 2021, time=2021-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996529, encodeId=6aa09965294e, content=好办法!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/f645756269ba45cba20b74d86f6e4d05/b0a88b1bdfc44cb79e79818ce296dbb9.jpg, createdBy=c2c55519856, createdName=wml_guyue, createdTime=Mon Jul 05 21:00:02 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996350, encodeId=939a9963508d, content=希望有效,临床好评, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Mon Jul 05 10:47:28 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996330, encodeId=e66699633068, content=真是解决了公共场合打嗝的尴尬, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Mon Jul 05 09:27:26 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996309, encodeId=f7e29963094c, content=学到新招了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ec235476032, createdName=ms1000001439107490, createdTime=Mon Jul 05 08:17:10 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036723, encodeId=12ee1036e2366, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Jul 05 01:08:14 CST 2021, time=2021-07-05, status=1, ipAttribution=)]
    2021-07-05 ms1000001439107490

    学到新招了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1734394, encodeId=c31f1e3439471, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Sep 17 08:08:14 CST 2021, time=2021-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729018, encodeId=2d8f1e2901838, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Feb 26 12:08:14 CST 2022, time=2022-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718728, encodeId=b2511e18728ba, content=<a href='/topic/show?id=b5e85463053' target=_blank style='color:#2F92EE;'>#打嗝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54630, encryptionId=b5e85463053, topicName=打嗝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8da32602155, createdName=hyf039, createdTime=Wed Oct 06 22:08:14 CST 2021, time=2021-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996529, encodeId=6aa09965294e, content=好办法!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/f645756269ba45cba20b74d86f6e4d05/b0a88b1bdfc44cb79e79818ce296dbb9.jpg, createdBy=c2c55519856, createdName=wml_guyue, createdTime=Mon Jul 05 21:00:02 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996350, encodeId=939a9963508d, content=希望有效,临床好评, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Mon Jul 05 10:47:28 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996330, encodeId=e66699633068, content=真是解决了公共场合打嗝的尴尬, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Mon Jul 05 09:27:26 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996309, encodeId=f7e29963094c, content=学到新招了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ec235476032, createdName=ms1000001439107490, createdTime=Mon Jul 05 08:17:10 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036723, encodeId=12ee1036e2366, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Jul 05 01:08:14 CST 2021, time=2021-07-05, status=1, ipAttribution=)]
    2021-07-05 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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JAMA子刊:打嗝停不下来?这个方法可能更有效!

打嗝即呃逆,指气从胃中上逆,喉间频频作声,声音急而短促。是一个生理上常见的现象,由横膈膜痉挛收缩引起的。

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