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JACC:主动脉瓣反流伴二尖瓣反流的特征研究

2020-07-15 MedSci原创 MedSci原创

二尖瓣反流(MR)加上血流动力学显着的慢性主动脉瓣反流(AR)的病因、机制和存活率目前还不清楚。

二尖瓣反流(MR)加上血流动力学显着的慢性主动脉瓣反流(AR)的病因、机制和存活率目前还不清楚。

本研究纳入分析了1239名中重度AR患者(平均年龄61 ± 18岁,男性占80%),其中86%患者为单纯性AR患者,14%患者为AR+MR。基线水平时,单纯AR患者与AR+MR患者在年龄上存在差异,性别比例、症状、房颤率、左室射血分数、左室舒张末期容积、三尖瓣反流情况和右室收缩压均存在明显差异(p < 0.0001)。经过平均5.2年时间的随访,纽约心功能分级、主动脉瓣手术、左室射血分数、左室收缩末期尺寸和容积指数、FMR的存在与全因死亡率独立相关(p≤0.004)。与单纯性AR患者相比,AR+MR+TR患者的死亡风险最高。

研究结果显示,在血流动力学改变的主动脉瓣反流患者中,二尖瓣反流的存在并不常见(约14%),与单纯性AR患者相比,AR+MR+TR患者的死亡风险最高。

原始出处:

Li-Tan Y et al.Concomitant Mitral Regurgitation in Patients With Chronic Aortic Regurgitation.JACC.2020 July.

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    2021-02-23 hbwxf
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    2020-07-17 wwzzly
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    2020-07-17 feifers
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    2020-07-16 医鸣惊人

    学习

    0

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