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Stroke:190万数据证实,青春期肥胖是导致中风的重要因素,或可高出常人2倍!

2021-05-13 MedSci原创 MedSci原创

关注青少年肥胖!

513日,发表在Stroke杂志的一项研究显示,无论是否患有2糖尿病,青春期肥胖均会显着增加成年后首次缺血性中风的风险。

在这项研究中,研究人员基于2项以色列人口国家数据库,对1900384名年龄在1620岁的青少年进行首次中风事件评估。体重指数根据美国疾病控制与预防中心进行了分类。

结果显示,1088例首次出现中风,其中921例缺血性中风和167例出血性中风,平均诊断年龄为41.0岁。青少年体重指数与缺血性中风的直接相关,而出血性中风的危险性则逐级增加。

具体而言,与体重正常者相比,体重超标的青少年在50岁之前的中风风险高2倍,而肥胖的青少年的风险则高3.4倍。与较低体重指数相比,即使处于正常体重指数的高分位的青少年也更可能发生中风风险。在调整性别,年龄和社会人口统计学混杂因素后,与体重指数在正常范围内的人相比,超重或肥胖的青少年中风的风险仍然很高,分别高于常人1.6倍和2.4倍。

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尽管青春期期间超重和肥胖是最常见问题,但研究人员惊讶地发现,2型糖尿病并不能解释增加青少年发生缺血性中风的风险,缺血性卒中甚至在30岁之前就已发生。目前,医学文献表明,中风可能会导致中风复发,心脏病发作和过早死亡。

研究人员表示,该研究强调了在青春期有效控制体重的重要性。然而,该研究也具有一些局限性,并非所有参与者都可以获得随访时的体重指数数据,这意味着无法评估肥胖随时间对中风风险的影响,也无法确定青春期体重指数的独立风险。

总之,无论是否患有糖尿病,青春期体重指数较高与后期发生卒中有显著关联,青少年肥胖症的患病率上升可能会增加中风风险。

原始出处

Aya BardugoBoris Fishman.et al.Body Mass Index in 1.9 Million Adolescents and Stroke in Young Adulthood.Stroke.https://doi.org/10.1161/STROKEAHA.120.033595

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  1. [GetPortalCommentsPageByObjectIdResponse(id=998853, encodeId=731999885394, content=学习了。控制体重很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e604701817, createdName=www.gongxuelei1987, createdTime=Mon Jul 12 18:20:41 CST 2021, time=2021-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275558, encodeId=61b812e5558a8, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat May 15 13:17:59 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965577, encodeId=f1a99655e7e3, content=所以更要减少不必要的甜食摄入,加强运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Fri May 14 15:53:12 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046054, encodeId=8f4210460549b, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Fri May 14 01:17:59 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965384, encodeId=bf1f9653842f, content=<a href='/topic/show?id=8e4616842bd' target=_blank style='color:#2F92EE;'>#Stroke#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16842, encryptionId=8e4616842bd, topicName=Stroke)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Thu May 13 23:05:43 CST 2021, time=2021-05-13, status=1, ipAttribution=)]
    2021-07-12 www.gongxuelei1987

    学习了。控制体重很重要

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=998853, encodeId=731999885394, content=学习了。控制体重很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e604701817, createdName=www.gongxuelei1987, createdTime=Mon Jul 12 18:20:41 CST 2021, time=2021-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275558, encodeId=61b812e5558a8, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat May 15 13:17:59 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965577, encodeId=f1a99655e7e3, content=所以更要减少不必要的甜食摄入,加强运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Fri May 14 15:53:12 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046054, encodeId=8f4210460549b, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Fri May 14 01:17:59 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965384, encodeId=bf1f9653842f, content=<a href='/topic/show?id=8e4616842bd' target=_blank style='color:#2F92EE;'>#Stroke#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16842, encryptionId=8e4616842bd, topicName=Stroke)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Thu May 13 23:05:43 CST 2021, time=2021-05-13, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=998853, encodeId=731999885394, content=学习了。控制体重很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e604701817, createdName=www.gongxuelei1987, createdTime=Mon Jul 12 18:20:41 CST 2021, time=2021-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275558, encodeId=61b812e5558a8, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat May 15 13:17:59 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965577, encodeId=f1a99655e7e3, content=所以更要减少不必要的甜食摄入,加强运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Fri May 14 15:53:12 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046054, encodeId=8f4210460549b, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Fri May 14 01:17:59 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965384, encodeId=bf1f9653842f, content=<a href='/topic/show?id=8e4616842bd' target=_blank style='color:#2F92EE;'>#Stroke#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16842, encryptionId=8e4616842bd, topicName=Stroke)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Thu May 13 23:05:43 CST 2021, time=2021-05-13, status=1, ipAttribution=)]
    2021-05-14 ms2000001361349190

    所以更要减少不必要的甜食摄入,加强运动

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=998853, encodeId=731999885394, content=学习了。控制体重很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e604701817, createdName=www.gongxuelei1987, createdTime=Mon Jul 12 18:20:41 CST 2021, time=2021-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275558, encodeId=61b812e5558a8, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat May 15 13:17:59 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965577, encodeId=f1a99655e7e3, content=所以更要减少不必要的甜食摄入,加强运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Fri May 14 15:53:12 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046054, encodeId=8f4210460549b, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Fri May 14 01:17:59 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965384, encodeId=bf1f9653842f, content=<a href='/topic/show?id=8e4616842bd' target=_blank style='color:#2F92EE;'>#Stroke#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16842, encryptionId=8e4616842bd, topicName=Stroke)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Thu May 13 23:05:43 CST 2021, time=2021-05-13, status=1, ipAttribution=)]
    2021-05-14 guging

    中风是俗称,应该称为缺血性卒中吧

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=998853, encodeId=731999885394, content=学习了。控制体重很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e604701817, createdName=www.gongxuelei1987, createdTime=Mon Jul 12 18:20:41 CST 2021, time=2021-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275558, encodeId=61b812e5558a8, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat May 15 13:17:59 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965577, encodeId=f1a99655e7e3, content=所以更要减少不必要的甜食摄入,加强运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Fri May 14 15:53:12 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046054, encodeId=8f4210460549b, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Fri May 14 01:17:59 CST 2021, time=2021-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965384, encodeId=bf1f9653842f, content=<a href='/topic/show?id=8e4616842bd' target=_blank style='color:#2F92EE;'>#Stroke#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16842, encryptionId=8e4616842bd, topicName=Stroke)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20221103/2796e00c9b4549e3b313ed9e7accc68f/b52d6d98bbe04782b5a4e2dd1ee80be2.jpeg, createdBy=078e1614372, createdName=MedSciZeng, createdTime=Thu May 13 23:05:43 CST 2021, time=2021-05-13, status=1, ipAttribution=)]
    2021-05-13 MedSciZeng

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