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Cancer Cell:胆管癌是如何发生的?又该如何预防?

2017-06-13 枫丹白露 来宝网

两种不同类型的癌症可以在肝脏发育。更常见的恶性肿瘤是由肝细胞产生的肝细胞癌。不常见的是肝脏胆管癌(胆管癌),其来源于胆管细胞或未分化肝细胞。两种癌症都难以治疗,近年来新诊断的病例数量有所增加。在美国,它们是今天癌症死亡的第二大原因,而且是新病例增长最快的癌症类型。

两种不同类型的癌症可以在肝脏发育。更常见的恶性肿瘤是由肝细胞产生的肝细胞癌。不常见的是肝脏胆管癌(胆管癌),其来源于胆管细胞或未分化肝细胞。两种癌症都难以治疗,近年来新诊断的病例数量有所增加。在美国,它们是今天癌症死亡的第二大原因,而且是新病例增长最快的癌症类型。德国癌症研究中心(Deutsches Krebsforschungszentrum,DKFZ)的Mathias Heikenwalder说:“到目前为止,我们几乎没有关于什么促进胆管癌的线索,因此我们没有可能使用药物来阻止这一过程。” “在我们目前的工作中,我们不仅确定了引起胆管细胞转化为癌症的关键信号途径,而且我们还展示了几种可能性来中断这种癌症促进过程。”目前研究的进一步主要贡献者是来自慕尼黑技术大学(TUM)的Heikenwalder的同事Dirk Haller,以及德国环境卫生研究中心(亥姆霍兹中兴慕尼黑),图宾根大学医院和图宾根大学的研究人员。科学家首先从小鼠和人类研究肝组织样本。在胆管癌的环境中,他们总是发现非常高水平的有害活性氧(ROS)。活性氧是否是原因?ROS通常发现在已经被炎症例如病毒性肝炎或酒精滥用中损伤

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    2017-11-11 维他命
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  5. 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    2017-06-14 1e1b8538m79(暂无匿称)

    不错的文章,值得一读

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jun 14 06:59:54 CST 2017, time=2017-06-14, status=1, ipAttribution=)]
    2017-06-14 luominglian113

    学习了,谢谢分享

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jun 14 06:59:54 CST 2017, time=2017-06-14, status=1, ipAttribution=)]
    2017-06-14 134****2080

    学习

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jun 14 06:59:54 CST 2017, time=2017-06-14, status=1, ipAttribution=)]
    2017-06-14 Norene

    学习了。。。。

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jun 14 06:59:54 CST 2017, time=2017-06-14, status=1, ipAttribution=)]
    2017-06-14 Jackie Li

    学习

    0

  10. 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    2017-06-14 doctorJiangchao

    继续关注。

    0

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