Baidu
map

JCEM:肢端肥大症患者经蝶骨手术后病情缓解的预测因素

2021-02-06 MedSci原创 MedSci原创

经蝶骨手术(TSS)是肢端肥大症患者首选的治疗方法。最大肿瘤直径和随机测量的GH浓度是肢端肥大症患者TSS后病情缓解的最佳预测指标。

经蝶骨手术(TSS)是肢端肥大症患者首选的治疗方法。识别早期不能手术治愈的患者尤为重要,既可以告知患者预期的治疗结局,也可以选择可能需要其他治疗的患者。近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,该研究旨在明确肢端肥大症患者接受TSS后病情缓解的预测因素。

研究人员从荷兰三个三级神经外科转诊中心收集到的回顾性数据进行了多中心研究。研究人员分析了2000年以来三个队列(格罗宁根、奈梅亨和鹿特丹,总计n=282)的临床数据。根据2010年共识标准,研究人员使用多元回归模型确定早期生化指标缓解(术后12周至1年)、长期缓解和胰岛素样生长因子-1(IGF-1)和生长激素(GH)相对降低的预测因素。

较大的最大肿瘤直径(OR为0.91,95%CI为0.87-0.96,p≤0.0001)与较低的早期生化指标缓解几率相关。较大的最大肿瘤直径(OR为0.93,95%CI为0.89-0.97,p=0.0022)和较高的随机测量的GH浓度(OR为0.98,95%CI为0.96-0.99,p=0.0053)与较低的肿瘤发生几率相关。

由此可见,最大肿瘤直径和随机测量的GH浓度是肢端肥大症患者TSS后病情缓解的最佳预测指标

原始出处:

Eva C Coopmans.et al.Predictors for remission after transsphenoidal surgery in acromegaly: a Dutch multicenter study.JCEM.2021.https://doi.org/10.1210/clinem/dgab069

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
    2021-02-22 smallant2015
  2. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
    2021-06-01 zhanglingyan

    学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
    2021-11-24 achengzhao
  6. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1778019, encodeId=57211e780194a, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Mon Feb 22 21:37:41 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765132, encodeId=1f961e651320e, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Apr 24 03:37:41 CST 2021, time=2021-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664772, encodeId=4c881664e725e, content=<a href='/topic/show?id=65b5818609b' target=_blank style='color:#2F92EE;'>#肢端肥大#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81860, encryptionId=65b5818609b, topicName=肢端肥大)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1cad25837873, createdName=654699882_84926994, createdTime=Mon Oct 18 14:37:41 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970161, encodeId=14659e0161ed, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b02f97369, createdName=zhanglingyan, createdTime=Tue Jun 01 20:48:54 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063401, encodeId=149a206340101, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Wed Nov 24 09:37:41 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264352, encodeId=0029126435258, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1271198, encodeId=ac6512e11985f, content=<a href='/topic/show?id=391f8186168' target=_blank style='color:#2F92EE;'>#肢端肥大症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81861, encryptionId=391f8186168, topicName=肢端肥大症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7db99, createdName=chg121, createdTime=Mon Feb 08 02:37:41 CST 2021, time=2021-02-08, status=1, ipAttribution=)]

相关资讯

JCEM:肢端肥大症患者的癌症发生率!

由此可见,在我们的研究中,肢端肥大症患者癌症的发病率略有增加,这是得到了23项研究的荟萃分析支持,虽然它也提示一些早期的研究存在选择偏倚。

超声心动图诊断肢端肥大症心肌病1例

患者男,25岁。因“反复胸闷、气喘2个月余”入院。查体:血压148/81mmHg,头部巨颅,颧骨高耸,眉弓高突,唇肥厚,鼻唇沟隆起,鼻宽舌大,心尖搏动增强、弥散,心脏相对浊音界向左下扩大,心率110次/min,律齐。手脚粗大肥厚,皮肤粗厚,双下肢中度水肿。辅助检查:生长激素(GH)>40↑;泌乳素287.94ng/ml↑;脑利钠肽1471pg/ml↑。

NEJM:肢端肥大症相关的回状头皮-病例报道

头皮上的皮肤增厚和皱纹,称为回状头皮,可以作为孤立的症状出现,或者可能与许多疾病有关,例如肢端肥大症,如本例患者所示。

2019 KES立场声明:生长抑素类似物治疗肢端肥大症

2019年3月,韩国内分泌学会(KES)发布了生长抑素类似物治疗肢端肥大症的立场声明,文章主要内容包括肢端肥大症药物治疗中生长抑素类似物的特征、适应证、应用剂量,应用时间间隔、药物转换以及术前应用等内容。

肢端肥大症并发扩张性心肌病患者行前列腺粒子植入术的麻醉管理1例

患者,男,66岁,身高178 cm,体质量70kg,因“前列腺癌”入院。既往垂体瘤病史40余年(间断服用溴隐亭),扩张性心肌病病史7年,高血压病史7年,血压(BP)最高180/120mmHg,口服利血平、美托洛尔和贝那普利控制血压,平时BP控制在120/80mmHg左右,曾有心衰病史,经内科治疗好转,目前心功能Ⅱ级。27年前行右眼外伤手术,目前右眼失明。

FDA批准也是**一个口服生长抑素类似物MYCAPSSA(奥曲肽)胶囊,治疗肢端肥大症

“整个肢端肥大症人群一直都在等待口服疗法,FDA批准了第一种口服生长抑素类似物,将会对该类患者的生活产生重大影响。”

Baidu
map
Baidu
map
Baidu
map