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CHC2017:只有15%学术研究有价值

2017-08-14 王斌、郑昕 中国循环杂志

“如今学术领域仅有15%的研究具有真正价值”,《英国医学杂志》(BMJ)荣誉副主编及 BMJ Open 主编 Trish Groves 教授说。

“如今学术领域仅有15%的研究具有真正价值”,《英国医学杂志》(BMJ)荣誉副主编及 BMJ Open 主编 Trish Groves 教授说。

他认为,从提出研究所关心的问题,到建立合理的设计和执行方案,到有效运行和管理研究项目,再到得出客观公正的研究结果,研究的各个环节都将影响研究成果的价值。

好的研究设计在其中起到重要作用。一个具有独创性的设计思路应该是先提出问题,收集背景资料,再提出合理假设,继而开展试验验证假设。

然而现实中很多的研究则恰恰相反:即根据得到的试验数据,分析、倒推出问题。这样的研究设计是低质量的,缺乏科学精神和独创性价值。

Groves教授强调了文章可重复性的重要性。方法学和结果的可重复性使得研究的推广性和可信度大幅度增高。

反之,选择性报道、数据挖掘、P值操控和数据操控等行为会严重降低研究的可重复性。

真实世界研究是近年来学术圈的热点之一。借用 China PEACE-3VD 研究的方法学文章,Groves 教授向听众阐述了一个好的真实世界研究所具备的特点:

一是确保研究在伦理范围内计划和实施;
二是按照预设方法发表研究方案;
三是避免选择性报道结果,减少研究的偏倚,使得研究全阶段的可重复性最大化。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=235840, encodeId=277d23584012, content=现在没价值不代表以后没价值啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLS3nbTc0lzBwDxSVnm5KA9vNmsZrjTSvKlld6teMf4RG4ZmZWRvC80GB7zl4TSib3BAoZgcCYpzxQ/132, createdBy=02681961038, createdName=若轩, createdTime=Tue Aug 22 00:35:53 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1552139, encodeId=7acf15521399b, content=<a href='/topic/show?id=2d194589f3' target=_blank style='color:#2F92EE;'>#CHC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4589, encryptionId=2d194589f3, topicName=CHC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cbf14265668, createdName=mei536, createdTime=Wed Aug 16 01:41:00 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233820, encodeId=4eb3233820d7, content=科技进步都是一点一滴逐渐积累的,没有大量的研究做基础,做对照,做借鉴,谈何有用的研究?没有人可以高瞻远瞩、预测未来,做研究之前就断定以后肯定有用。当然,社会制度造就的论文导向所产生的不良现象另当别论。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83er3buhru0LAsyg84LKFlUu9TbQzMqdkJrVdYDBNWQleZia9xknRyucu90N0HziaMyKJeyiaOt0pxKZsg/132, createdBy=38e21963843, createdName=大黑牛, createdTime=Tue Aug 15 14:08:14 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233692, encodeId=14e3233692b5, content=已学习分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20231215/ac08b4d4cecf4bd3b9af86e00dcbca38/f6b6a60efd854ff191eb5c611ec7dd12.jpg, createdBy=8afb2071832, createdName=15938038573红旗飘飘, createdTime=Tue Aug 15 06:44:22 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233536, encodeId=7b5123353606, content=有道理,中国的学术研究有价值的有没有15%?大家发表的研究论文可能很多自已都不会看,是用来晋升职称的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=712c1945140, createdName=心不在烟, createdTime=Mon Aug 14 19:47:14 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233462, encodeId=497223346220, content=学习了,有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Mon Aug 14 11:19:21 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-22 若轩

    现在没价值不代表以后没价值啊

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=235840, encodeId=277d23584012, content=现在没价值不代表以后没价值啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLS3nbTc0lzBwDxSVnm5KA9vNmsZrjTSvKlld6teMf4RG4ZmZWRvC80GB7zl4TSib3BAoZgcCYpzxQ/132, createdBy=02681961038, createdName=若轩, createdTime=Tue Aug 22 00:35:53 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1552139, encodeId=7acf15521399b, content=<a href='/topic/show?id=2d194589f3' target=_blank style='color:#2F92EE;'>#CHC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4589, encryptionId=2d194589f3, topicName=CHC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cbf14265668, createdName=mei536, createdTime=Wed Aug 16 01:41:00 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233820, encodeId=4eb3233820d7, content=科技进步都是一点一滴逐渐积累的,没有大量的研究做基础,做对照,做借鉴,谈何有用的研究?没有人可以高瞻远瞩、预测未来,做研究之前就断定以后肯定有用。当然,社会制度造就的论文导向所产生的不良现象另当别论。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83er3buhru0LAsyg84LKFlUu9TbQzMqdkJrVdYDBNWQleZia9xknRyucu90N0HziaMyKJeyiaOt0pxKZsg/132, createdBy=38e21963843, createdName=大黑牛, createdTime=Tue Aug 15 14:08:14 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233692, encodeId=14e3233692b5, content=已学习分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20231215/ac08b4d4cecf4bd3b9af86e00dcbca38/f6b6a60efd854ff191eb5c611ec7dd12.jpg, createdBy=8afb2071832, createdName=15938038573红旗飘飘, createdTime=Tue Aug 15 06:44:22 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233536, encodeId=7b5123353606, content=有道理,中国的学术研究有价值的有没有15%?大家发表的研究论文可能很多自已都不会看,是用来晋升职称的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=712c1945140, createdName=心不在烟, createdTime=Mon Aug 14 19:47:14 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233462, encodeId=497223346220, content=学习了,有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Mon Aug 14 11:19:21 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-16 mei536
  3. [GetPortalCommentsPageByObjectIdResponse(id=235840, encodeId=277d23584012, content=现在没价值不代表以后没价值啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLS3nbTc0lzBwDxSVnm5KA9vNmsZrjTSvKlld6teMf4RG4ZmZWRvC80GB7zl4TSib3BAoZgcCYpzxQ/132, createdBy=02681961038, createdName=若轩, createdTime=Tue Aug 22 00:35:53 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1552139, encodeId=7acf15521399b, content=<a href='/topic/show?id=2d194589f3' target=_blank style='color:#2F92EE;'>#CHC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4589, encryptionId=2d194589f3, topicName=CHC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cbf14265668, createdName=mei536, createdTime=Wed Aug 16 01:41:00 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233820, encodeId=4eb3233820d7, content=科技进步都是一点一滴逐渐积累的,没有大量的研究做基础,做对照,做借鉴,谈何有用的研究?没有人可以高瞻远瞩、预测未来,做研究之前就断定以后肯定有用。当然,社会制度造就的论文导向所产生的不良现象另当别论。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83er3buhru0LAsyg84LKFlUu9TbQzMqdkJrVdYDBNWQleZia9xknRyucu90N0HziaMyKJeyiaOt0pxKZsg/132, createdBy=38e21963843, createdName=大黑牛, createdTime=Tue Aug 15 14:08:14 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233692, encodeId=14e3233692b5, content=已学习分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20231215/ac08b4d4cecf4bd3b9af86e00dcbca38/f6b6a60efd854ff191eb5c611ec7dd12.jpg, createdBy=8afb2071832, createdName=15938038573红旗飘飘, createdTime=Tue Aug 15 06:44:22 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233536, encodeId=7b5123353606, content=有道理,中国的学术研究有价值的有没有15%?大家发表的研究论文可能很多自已都不会看,是用来晋升职称的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=712c1945140, createdName=心不在烟, createdTime=Mon Aug 14 19:47:14 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233462, encodeId=497223346220, content=学习了,有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Mon Aug 14 11:19:21 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-15 大黑牛

    科技进步都是一点一滴逐渐积累的,没有大量的研究做基础,做对照,做借鉴,谈何有用的研究?没有人可以高瞻远瞩、预测未来,做研究之前就断定以后肯定有用。当然,社会制度造就的论文导向所产生的不良现象另当别论。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=235840, encodeId=277d23584012, content=现在没价值不代表以后没价值啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLS3nbTc0lzBwDxSVnm5KA9vNmsZrjTSvKlld6teMf4RG4ZmZWRvC80GB7zl4TSib3BAoZgcCYpzxQ/132, createdBy=02681961038, createdName=若轩, createdTime=Tue Aug 22 00:35:53 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1552139, encodeId=7acf15521399b, content=<a href='/topic/show?id=2d194589f3' target=_blank style='color:#2F92EE;'>#CHC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4589, encryptionId=2d194589f3, topicName=CHC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cbf14265668, createdName=mei536, createdTime=Wed Aug 16 01:41:00 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233820, encodeId=4eb3233820d7, content=科技进步都是一点一滴逐渐积累的,没有大量的研究做基础,做对照,做借鉴,谈何有用的研究?没有人可以高瞻远瞩、预测未来,做研究之前就断定以后肯定有用。当然,社会制度造就的论文导向所产生的不良现象另当别论。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83er3buhru0LAsyg84LKFlUu9TbQzMqdkJrVdYDBNWQleZia9xknRyucu90N0HziaMyKJeyiaOt0pxKZsg/132, createdBy=38e21963843, createdName=大黑牛, createdTime=Tue Aug 15 14:08:14 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233692, encodeId=14e3233692b5, content=已学习分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20231215/ac08b4d4cecf4bd3b9af86e00dcbca38/f6b6a60efd854ff191eb5c611ec7dd12.jpg, createdBy=8afb2071832, createdName=15938038573红旗飘飘, createdTime=Tue Aug 15 06:44:22 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233536, encodeId=7b5123353606, content=有道理,中国的学术研究有价值的有没有15%?大家发表的研究论文可能很多自已都不会看,是用来晋升职称的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=712c1945140, createdName=心不在烟, createdTime=Mon Aug 14 19:47:14 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233462, encodeId=497223346220, content=学习了,有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Mon Aug 14 11:19:21 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-15 15938038573红旗飘飘

    已学习分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=235840, encodeId=277d23584012, content=现在没价值不代表以后没价值啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLS3nbTc0lzBwDxSVnm5KA9vNmsZrjTSvKlld6teMf4RG4ZmZWRvC80GB7zl4TSib3BAoZgcCYpzxQ/132, createdBy=02681961038, createdName=若轩, createdTime=Tue Aug 22 00:35:53 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1552139, encodeId=7acf15521399b, content=<a href='/topic/show?id=2d194589f3' target=_blank style='color:#2F92EE;'>#CHC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4589, encryptionId=2d194589f3, topicName=CHC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cbf14265668, createdName=mei536, createdTime=Wed Aug 16 01:41:00 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233820, encodeId=4eb3233820d7, content=科技进步都是一点一滴逐渐积累的,没有大量的研究做基础,做对照,做借鉴,谈何有用的研究?没有人可以高瞻远瞩、预测未来,做研究之前就断定以后肯定有用。当然,社会制度造就的论文导向所产生的不良现象另当别论。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83er3buhru0LAsyg84LKFlUu9TbQzMqdkJrVdYDBNWQleZia9xknRyucu90N0HziaMyKJeyiaOt0pxKZsg/132, createdBy=38e21963843, createdName=大黑牛, createdTime=Tue Aug 15 14:08:14 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233692, encodeId=14e3233692b5, content=已学习分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20231215/ac08b4d4cecf4bd3b9af86e00dcbca38/f6b6a60efd854ff191eb5c611ec7dd12.jpg, createdBy=8afb2071832, createdName=15938038573红旗飘飘, createdTime=Tue Aug 15 06:44:22 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233536, encodeId=7b5123353606, content=有道理,中国的学术研究有价值的有没有15%?大家发表的研究论文可能很多自已都不会看,是用来晋升职称的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=712c1945140, createdName=心不在烟, createdTime=Mon Aug 14 19:47:14 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233462, encodeId=497223346220, content=学习了,有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Mon Aug 14 11:19:21 CST 2017, time=2017-08-14, status=1, ipAttribution=)]
    2017-08-14 心不在烟

    有道理,中国的学术研究有价值的有没有15%?大家发表的研究论文可能很多自已都不会看,是用来晋升职称的。

    0

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    2017-08-14 明崖

    学习了,有道理

    0

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