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BMC Anesthesiol:单次给予地佐辛可抑制七氟醚-瑞芬太尼麻醉学龄前儿童的苏醒躁动

2017-12-22 王子君 “罂粟花”微信号

把100例择期腹腔镜高位结扎疝囊腹股沟疝修补术的学龄前儿童随机分为2组,C组(n=50)术后给予10ml乳酸林格液和D组术后给予10ml含0.1mg/kg的乳酸林格液。

背景与目的:苏醒躁动(EA)是学龄前儿童全麻苏醒期的常见表现。本研究评估了地佐辛对七氟醚复合瑞芬太尼麻醉的学龄前儿童苏醒躁动的安全性和有效性。

方  法:把100例择期腹腔镜高位结扎疝囊腹股沟疝修补术的学龄前儿童随机分为2组,C组(n=50)术后给予10ml乳酸林格液和D组术后给予10ml含0.1mg/kg的乳酸林格液。

结  果:D组的EA发生率(定义为在PACU内Aono评分≥3分或小儿麻醉苏醒躁动(PAED)评分≥10)(10%vs. 76%)和严重EA(PAED评分≥13分)(12%vs. 76%)的百分比明显低于C组 (P < 0.05)。D组小儿术后疼痛评分(CHIPPS)明显低于C组(1.2±0.5 vs. 5.2±0.6;P<0.05)。C组患儿需要给予芬太尼治疗(18% vs 4%)或丙泊酚治疗(20% vs 0)的人数明显多于D组。两组其他术后相关观察指标的差异无统计学意义。

结  论:0.1mg / kg地佐辛降低了在七氟醚-瑞芬太尼麻醉下腹腔镜高位结扎疝囊腹股沟疝修补术的学龄前儿童EA的发生率和严重程度。

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    2017-12-24 xue8602
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  8. 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  9. 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time=2018-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384809, encodeId=fc5c13848094a, content=<a href='/topic/show?id=93918690e81' target=_blank style='color:#2F92EE;'>#芬太尼#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86907, encryptionId=93918690e81, topicName=芬太尼)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d139492, createdName=xue8602, createdTime=Sun Dec 24 13:36:00 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405259, encodeId=d9201405259a2, content=<a href='/topic/show?id=568068e40fa' target=_blank style='color:#2F92EE;'>#瑞芬太尼#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68740, encryptionId=568068e40fa, topicName=瑞芬太尼)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2a92531888, createdName=qidongfanjian, createdTime=Sun Dec 24 13:36:00 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1412678, encodeId=6b4f14126e8cf, content=<a href='/topic/show?id=1c2f195092d' target=_blank style='color:#2F92EE;'>#七氟醚#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19509, encryptionId=1c2f195092d, topicName=七氟醚)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a102881238, createdName=linagood, createdTime=Sun Dec 24 13:36:00 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588298, encodeId=d2171588298ec, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Sun Dec 24 13:36:00 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272081, encodeId=85d22e208112, content=学习学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Sun Dec 24 10:53:27 CST 2017, time=2017-12-24, status=1, ipAttribution=)]
    2017-12-24 skhzy
  10. 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