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J Periodontol: SAPM治疗牙本质过敏症

2018-07-21 MedSci MedSci原创

通常认为,患者自述的牙本质过敏症[DHS]疼痛与牙周病相关。该试验性临床研究使用自制肽基质[SAPM]凝胶(实验)与8%精氨酸和碳酸钙[ACC]牙膏(对照)治疗DHS的效果。

通常认为,患者自述的牙本质过敏症[DHS]疼痛与牙周病相关。该试验性临床研究使用自制肽基质[SAPM]凝胶(实验)与8%精氨酸和碳酸钙[ACC]牙膏(对照)治疗DHS的效果。

共有50名有牙周支持治疗史的患者参加了这项前瞻性随机临床研究,其中45名(实验组:n = 22;对照组:n = 23)完成了所有的研究。实验组患者在1周内进行SAPM凝胶的诊室外应用,而对照组患者在90天内进行ACC牙膏的诊室外应用。通过视觉模拟量表[VAS]对DHS进行评估,并通过问卷评估患者对疼痛缓解的感知。记录扫描电子显微镜图像以研究对照和测试产品的牙本质小管闭塞情况。

结果:在整个研究中,SAPM和ACC均显着降低了患者的DHS,患者问卷表明测试组患者满意度在较早时间点较高。

SAPM凝胶和ACC牙膏均成功地缓解了DHS,并且在整个90天的研究期间VAS和言语反应量表(VRS)上显示出类似的结果。患者问卷和第7天和第90天的无痛患者数量所示,使用SAPM的新治疗方案在第7天患者满意度更高。

原始出处:

Markus Schlee, et al. Self‐assembling peptide matrix for treatment of dentin hypersensitivity: A randomized controlled clinical trial. Journal of Periodontology. 2018 June. doi: 10.1002/JPER.17-0429

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    2018-12-29 zz70
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    2019-01-15 feather89
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1975876, encodeId=efe719e58767f, content=<a href='/topic/show?id=15916e57157' target=_blank style='color:#2F92EE;'>#牙本质过敏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67571, encryptionId=15916e57157, topicName=牙本质过敏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87531, createdName=klivis, createdTime=Sat Feb 02 06:30:00 CST 2019, time=2019-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898181, encodeId=571e18981818e, content=<a href='/topic/show?id=8904158e9e7' target=_blank style='color:#2F92EE;'>#SAP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15879, encryptionId=8904158e9e7, topicName=SAP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sat Dec 29 06:30:00 CST 2018, time=2018-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727452, encodeId=337d1e2745253, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Jan 15 05:30:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441905, encodeId=71201441905d2, content=<a href='/topic/show?id=67526e55924' target=_blank style='color:#2F92EE;'>#牙本质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67559, encryptionId=67526e55924, topicName=牙本质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=37364903098, createdName=ms8538335253054589, createdTime=Mon Jul 23 12:30:00 CST 2018, time=2018-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516454, encodeId=1a6215164545d, content=<a href='/topic/show?id=0c06940668a' target=_blank style='color:#2F92EE;'>#过敏症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94066, encryptionId=0c06940668a, topicName=过敏症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def310968681, createdName=ms1948154235210413, createdTime=Mon Jul 23 12:30:00 CST 2018, time=2018-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333234, encodeId=7de733323430, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jul 22 00:34:49 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333228, encodeId=80e7333228cb, content=用SAPM治疗牙本质过敏症,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Jul 22 00:07:02 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1975876, encodeId=efe719e58767f, content=<a href='/topic/show?id=15916e57157' target=_blank style='color:#2F92EE;'>#牙本质过敏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67571, encryptionId=15916e57157, topicName=牙本质过敏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87531, createdName=klivis, createdTime=Sat Feb 02 06:30:00 CST 2019, time=2019-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898181, encodeId=571e18981818e, content=<a href='/topic/show?id=8904158e9e7' target=_blank style='color:#2F92EE;'>#SAP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15879, encryptionId=8904158e9e7, topicName=SAP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sat Dec 29 06:30:00 CST 2018, time=2018-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727452, encodeId=337d1e2745253, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Jan 15 05:30:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441905, encodeId=71201441905d2, content=<a href='/topic/show?id=67526e55924' target=_blank style='color:#2F92EE;'>#牙本质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67559, encryptionId=67526e55924, topicName=牙本质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=37364903098, createdName=ms8538335253054589, createdTime=Mon Jul 23 12:30:00 CST 2018, time=2018-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516454, encodeId=1a6215164545d, content=<a href='/topic/show?id=0c06940668a' target=_blank style='color:#2F92EE;'>#过敏症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94066, encryptionId=0c06940668a, topicName=过敏症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def310968681, createdName=ms1948154235210413, createdTime=Mon Jul 23 12:30:00 CST 2018, time=2018-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333234, encodeId=7de733323430, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jul 22 00:34:49 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333228, encodeId=80e7333228cb, content=用SAPM治疗牙本质过敏症,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Jul 22 00:07:02 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
    2018-07-22 飛歌

    学习了很有用不错

    0

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    2018-07-22 liumin1987

    用SAPM治疗牙本质过敏症,学习了。

    0

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