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JAHA:近40%无症状冠脉痉挛或被误诊为早期复极综合征

2018-02-13 岱西 中国循环杂志

发表在JAHA上的一项研究显示,约40%的伴有室颤和下侧壁J波的冠脉痉挛患者在首次室颤发作时无胸痛症状,被误诊为早期复极综合征。


发表在JAHA上的一项研究显示,约40%的伴有室颤和下侧壁J波的冠脉痉挛患者在首次室颤发作时无胸痛症状,被误诊为早期复极综合征。
 
研究者介绍说,早期复极综合征和冠脉痉挛都可能诱发无结构性心脏病患者发生室颤。但如何鉴别二者还是颇具挑战,冠脉激发试验或可助一臂之力,并优化药物治疗。
 
对于冠脉痉挛患者,给予抗心绞痛药物治疗预防室颤复发很重要;而对于早期复极综合征患者,给予奎尼丁、西洛他唑和苄普地尔则有效。
 
在这项研究中,共纳入34例特发性室颤和下侧壁J波患者。其中13例有冠脉痉挛,8例在冠脉造影中激发试验证实,5例有自发性ST段抬高。
 
这13例冠脉痉挛患者中,5例在室颤前或室颤时无胸痛等症状,即发生无症状冠脉痉挛。其他21例患者考虑早期复极综合征,激发试验阴性也无胸痛症状。
 
随访92个月,冠脉痉挛患者接受抗心绞痛药物治疗预后良好;而余者21例早期复极综合征患者有4例室颤复发,在接受奎尼丁、西洛他唑和贝普地尔单药或联合治疗预防室颤复发效果较好。

原始出处:

Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, et al. Significance of Coronary Artery Spasm Diagnosis in Patients With Early Repolarization Syndrome. Journal of the American Heart Association. 2018, 7: e007942.

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    2018-02-20 杨利洪

    学习了提高了

    0

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    2018-02-17 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

  4. 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channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Feb 15 13:27:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287734, encodeId=e58928e73411, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Feb 13 23:46:40 CST 2018, time=2018-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287731, encodeId=bd9928e731a1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
    2018-02-15 yfjms

    学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2025402, encodeId=797e202540281, content=<a href='/topic/show?id=395730989d4' target=_blank style='color:#2F92EE;'>#冠脉痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30989, encryptionId=395730989d4, topicName=冠脉痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Tue Jan 15 11:27:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289522, encodeId=905c2895224d, content=学习了提高了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Tue Feb 20 22:00:30 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channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Feb 15 13:27:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287734, encodeId=e58928e73411, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Feb 13 23:46:40 CST 2018, time=2018-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287731, encodeId=bd9928e731a1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
    2018-02-15 zhaohui6731
  6. [GetPortalCommentsPageByObjectIdResponse(id=2025402, encodeId=797e202540281, content=<a href='/topic/show?id=395730989d4' target=_blank style='color:#2F92EE;'>#冠脉痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30989, encryptionId=395730989d4, topicName=冠脉痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Tue Jan 15 11:27:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289522, encodeId=905c2895224d, content=学习了提高了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Tue Feb 20 22:00:30 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channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Feb 15 13:27:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287734, encodeId=e58928e73411, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Feb 13 23:46:40 CST 2018, time=2018-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287731, encodeId=bd9928e731a1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
    2018-02-15 apoenzyme
  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
  8. 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channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Feb 15 13:27:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287734, encodeId=e58928e73411, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Feb 13 23:46:40 CST 2018, time=2018-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287731, encodeId=bd9928e731a1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=2025402, encodeId=797e202540281, content=<a href='/topic/show?id=395730989d4' target=_blank style='color:#2F92EE;'>#冠脉痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30989, encryptionId=395730989d4, topicName=冠脉痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Tue Jan 15 11:27:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289522, encodeId=905c2895224d, content=学习了提高了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Tue Feb 20 22:00:30 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channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Feb 15 13:27:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287734, encodeId=e58928e73411, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Tue Feb 13 23:46:40 CST 2018, time=2018-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287731, encodeId=bd9928e731a1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
    2018-02-13 orangesking

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Feb 13 23:29:48 CST 2018, time=2018-02-13, status=1, ipAttribution=)]
    2018-02-13 清风拂面

    谢谢分享学习

    0

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23岁就心梗,最终诊断是啥?

23岁、无冠心病危险因素却出现胸痛 男性患者,23岁,因“间断胸痛1天”入院。入院前一天,凌晨 3:00 在睡眠中突发胸痛,疼痛剧烈并伴有出汗,持续约 2 小时自行缓解,未诊治;6:00 再发胸痛 10分钟,自行缓解;7:50 就诊于当地医院,查胸片、心电图显示:V2 - V6 ST段抬高 0.05 - 0.3 mv 伴 T波高尖,23:00胸痛再发,程度同前,呈持续性。 既往

病例分享:间断胸痛怀疑心梗,原因却是另一种致命性疾病

江西省南昌大学第二附属医院游志刚、黄琳等报道了这样一例“一曲三折”的病例。

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