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Sci Rep: 贫血可增加脑卒中患者死亡的风险

2016-06-17 MedSci MedSci原创

贫血对脑卒中患者预后的影响仍不一致。研究者进行了一项队列研究的荟萃分析,评估有无贫血的卒中患者的死亡风险。系统的搜索PubMed,中国国家知识基础设施工程,web of science 和万方数据库,以确定从数据库开始到2015年11月的相关研究。汇集估计比值比与95%CI。进行亚组分析和敏感性分析。研究者用Begg's漏斗图和Egger测试来检测潜在的发表偏倚。这项荟萃分析包括十三个队列研究,共

贫血对脑卒中患者预后的影响仍不一致。研究者进行了一项队列研究的荟萃分析,评估有无贫血的卒中患者的死亡风险。

系统的搜索PubMed,CNKI,web of science 和万方数据库,以确定从数据库开始到2015年11月的相关研究。汇集估计比值比与95%CI。进行亚组分析和敏感性分析。研究者用Begg's漏斗图和Egger测试来检测潜在的发表偏倚。

这项荟萃分析包括十三个队列研究,共有19239例脑卒中患者。异质性研究(I(2) = 59%,P = 0.031  )。随机效应模型的结果表明,贫血与脑卒中患者死亡风险增加相关(校正OR   = 1.39,95%CI:1.22-1.58,P<0.001  )。亚组分析与总结果一致。

这项13个队列荟萃分析研究发现,贫血增加卒中患者的死亡风险。未来应进行更长随访的研究,证实这一发现,并探讨其可能的机制。

原始出处:

Li Z, Zhou T, et al. Anemia increases the mortality risk in patients with stroke: A meta-analysis of cohort studies. Sci Rep. 2016 May 23.

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    2016-10-12 ylzr123

    好文,值得推荐。

    0

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    2016-06-23 微分

    学习了,加油

    0

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    2016-06-18 沉心多思

    好文章,值得学习

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