Obstet Gynecol：预防艾滋病母婴传播有哪些机会？

2017-03-21 xing.T MedSci原创

尽管患者得到了高水平的护理及随访，但一小部分的HIV感染的孕妇会将病毒传播给胎儿。这个病例系列为围产期艾滋病的传播的影响因素提供了新的认识，并可以为制定预防艾滋病毒母婴传播的新战略提供依据。

最近，妇产科领域权威杂志Obstetrics and Gynecology上发表了一篇研究文章，研究人员旨在明确预防艾滋病母婴途径传播的有效机会。

研究人员审查了在2002年到2009年之间入选美国国际母儿青少年艾滋病临床试验前瞻性队列研究的艾滋病感染的妇女生产的HIV感染儿童的数据。研究人员描述了HIV感染的婴儿及其母亲的特征，以及描述了其母亲的临床治疗。

该研究共观察了1857名活产婴儿，其中有12例发生母婴传播艾滋病毒感染，艾滋病毒感染妇女的活产儿母婴传播艾滋病患病率为0.65例/每名100活产儿（95％可信区间为0.33-1.13）。四例患者的传播发生在子宫内，三例发生于围产期，五例婴儿尚不能确定感染时间。这12例患者均没有进行母乳喂养。七名女性接近分娩期时，其血浆病毒载量大于400复制数/mL。6名妇女在怀孕期间接受了不到11周的抗逆转录病毒治疗，这些孕妇中有3名出现早产。一名妇女在怀孕期间没有接受抗逆转录病毒治疗，因为她在产后才被诊断为艾滋病。6名病人对抗逆转录病毒治疗依从性差，病毒载量大于1000拷贝数/ mL的5个母亲中有4个孩子早产。有五个妇女由剖腹产分娩，四个没有选择性剖宫产分娩，只有一名妇女选择性剖腹产分娩来预防艾滋病。

尽管患者得到了高水平的护理及随访，但一小部分的HIV感染的孕妇会将病毒传播给胎儿。这个病例系列为围产期艾滋病的传播的影响因素提供了新的认识，并可以为制定预防艾滋病毒母婴传播的新战略提供依据。

原始出处：

Scott, Gwendolyn B, et al. Missed Opportunities for Prevention of Mother-to-Child Transmission of Human Immunodeficiency Virus.Obstetrics & Gynecology.2017. http://journals.lww.com/greenjournal/Abstract/publishahead/Missed_Opportunities_for_Prevention_of.98450.aspx

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卢洪洲：艾滋病合并中枢神经系统感染的诊断治疗（上）

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2017-07-18 1249842em09(暂无昵称)

#NEC#

82 0
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2017-05-28 yhy100200

#TET#

90 0
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2017-04-26 dhzzm

值得推广，普及，政府应引起高度重视

129 0
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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-04-18 dhzzm

学习了分享了

132 0
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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-03-27 dhzzm

学习了，分享了

121 0
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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-03-23 zhouqu_8

#母婴#

97 0
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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-03-22 laymankey

感谢分享一下！

107 0
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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-03-22 一个字-牛

学习了

128 0
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createdTime=Thu Mar 23 13:20:00 CST 2017, time=2017-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182011, encodeId=6e171820115f, content=感谢分享一下！, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20971999626, createdName=laymankey, createdTime=Wed Mar 22 23:26:18 CST 2017, time=2017-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=181960, encodeId=3c821819609e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Wed Mar 22 13:22:23 CST 2017, time=2017-03-22, status=1, ipAttribution=), 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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-03-22 1e0e5697m83(暂无匿称)

henhap

86 0
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createdName=明月清辉, createdTime=Wed Mar 22 08:15:19 CST 2017, time=2017-03-22, status=1, ipAttribution=)]
2017-03-22 明月清辉

谢谢分享，学习了

95 0

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