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J Dent:一种全新的季铵硅烷类窝洞消毒剂对树脂-牙本质粘接持久性的影响

2017-03-24 MedSci MedSci原创

这篇报道研究的目的在于检测一种全新的季铵硅烷类(QAS)窝洞消毒剂对人牙髓细胞活力、对牙本质粘接耐久性以及简化了的酸蚀-冲洗-粘接过程中纳米渗漏的影响。

这篇报道研究的目的在于检测一种全新的季铵硅烷类(QAS)窝洞消毒剂对人牙髓细胞活力、对牙本质粘接耐久性以及简化了的酸蚀-冲洗-粘接过程中纳米渗漏的影响。

研究将牙本质表面酸蚀过的第三磨牙随机分为两组:Adper? Single Bond 2粘接剂组和Prime & Bond? NT?粘接剂组。每组牙齿随机用5种不同的窝洞消毒剂进行窝洞清洗(n=6):组1:去离子水(对照);组2:2%的氯已定(CHX);组3:2% QAS;组4:5% QAS;组5:10% QAS。在酸蚀后的牙本质表面进行窝洞消毒20 s,随后涂布粘接剂。粘接后的牙齿分别于24 h、6个月和12个月断面切开进行粘接强度测试。MTT法检测人牙髓细胞的活力。粘接强度的数据进行3因素方差分析和T检验。接触界面的纳米渗漏分别在术后24 h和12月通过Kruskal-Wallis法检测。

结果显示,粘接强度在不同消毒剂、不同时间均表现出显着性差异(P<0.001);而不同粘接剂对粘接强度未发现有明显不同(P=0.203)。术后12个月,2% QAS窝洞消毒剂依旧可以保持两种不同粘接剂的粘接强度,并且减少接触界面的纳米渗漏。细胞活力最低组为2% CHX,其次为2% QAS和对照组。

结论:与2% CHX相比,2% QAS窝洞消毒剂具有更好的细胞活性,并且对于不论即刻或者持久的粘接强度均未有不良影响。

原始出处:

Umer D, Yiu CK, et al. Effect of a novel quaternary ammonium silane cavity disinfectant on durability of resin-dentine bond. J Dent. 2017 Mar 14. pii: S0300-5712(17)30060-X. doi: 10.1016/j.jdent.2017.03.003.

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    2017-03-25 huperzia
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    2017-03-25 chenshujs

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