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Circulation:勃起功能障碍与心血管事件独立相关

2018-07-03 佚名 嘉音

6月11日,在线发表于《Circulation》杂志上的一项研究表明,男性勃起功能障碍(ED)与心血管事件独立相关,意味着ED是心血管疾病的早期预警。

6月11日,在线发表于《Circulation》杂志上的一项研究表明,男性勃起功能障碍(ED)与心血管事件独立相关,意味着ED是心血管疾病的早期预警。

ED与心血管疾病(CVD)有相同的危险因素,包括肥胖、高血压代谢综合征糖尿病、吸烟;ED与CVD也有共同的潜在病理机制,比如内皮功能紊乱、炎症、动脉硬化。尽管有这些联系,ED作为CVD事件的独立预测因子的证据还是有限。

约翰霍普金斯大学医学院的S.M.Iftekhar Uddin博士及其同事利用多民族动脉粥样硬化研究考察自我报告的ED预测冠心病和心血管疾病的发病率。研究纳入1914例男性受试者,并随访了3.8年。

研究者发现45.8%的受试者有ED。这些受试者患有糖尿病,遗传性冠心病,使用β-受体阻滞剂、抗高血压药、降脂与抗抑郁药物的可能性增加。随访期间,发生了40例冠心病事件,75例心血管疾病事件,有ED和没有ED的受试者在冠心病和心血管疾病方面有显著的不同(冠心病3.4%对1.4%;心血管疾病6.3%对2.6%)。

ED是心血管疾病事件的重要预测因子(HR,1.9),而ED与冠心病事件没有显著的关联。在横断面研究中,早期心血管疾病事件与ED显著相关(OR,2.1);随着用药和抑郁症的调整,两者之间的相关性减弱,但仍然很显著(OR,1.7)。

研究者说:“我们的发现增强了ED与心血管事件发病率独立相关的已有证据,并且对风险分层具有重要的临床意义。”

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    2019-04-30 habb
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    2018-07-09 大爰

    学习并分享!!

    0

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    2018-07-06 1039415152

    好有意思

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1643544, encodeId=789916435448e, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Nov 07 05:01:00 CST 2018, time=2018-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771155, encodeId=43a61e71155ea, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Tue Apr 30 03:01:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330348, encodeId=77f2330348a2, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Mon Jul 09 09:17:01 CST 2018, time=2018-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329706, encodeId=c588329e066e, content=好有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161217/IMG5854E0519E0D81311.jpg, createdBy=3ff51679470, createdName=1039415152, createdTime=Fri Jul 06 10:05:41 CST 2018, time=2018-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421168, encodeId=52161421168f5, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Jul 05 13:01:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502731, encodeId=a57c1502e319a, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Thu Jul 05 13:01:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329076, encodeId=54c53290e668, content=学习了.有用的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Jul 03 23:11:45 CST 2018, time=2018-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329048, encodeId=0cc332904807, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Tue Jul 03 22:15:22 CST 2018, time=2018-07-03, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1643544, encodeId=789916435448e, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Wed Nov 07 05:01:00 CST 2018, time=2018-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771155, encodeId=43a61e71155ea, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Tue Apr 30 03:01:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330348, encodeId=77f2330348a2, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Mon Jul 09 09:17:01 CST 2018, time=2018-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329706, encodeId=c588329e066e, content=好有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161217/IMG5854E0519E0D81311.jpg, createdBy=3ff51679470, createdName=1039415152, createdTime=Fri Jul 06 10:05:41 CST 2018, time=2018-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421168, encodeId=52161421168f5, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Jul 05 13:01:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502731, encodeId=a57c1502e319a, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Thu Jul 05 13:01:00 CST 2018, time=2018-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329076, encodeId=54c53290e668, content=学习了.有用的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Jul 03 23:11:45 CST 2018, time=2018-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329048, encodeId=0cc332904807, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Tue Jul 03 22:15:22 CST 2018, time=2018-07-03, status=1, ipAttribution=)]
    2018-07-03 明崖

    学习了.有用的研究

    0

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    2018-07-03 天地飞扬

    了解一下.谢谢分享!

    0

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