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吉利德HIV鸡尾酒疗法获FDA批准,年销售超10亿美元指日可待

2016-03-08 佚名 不详

吉利德公司HIV联合治疗方法得到FDA批准,这为吉利德公司在该治疗领域取得领袖地位奠定了一块基石。 此次获批的新药,名为Odefsey,是恩曲他滨(商品名Emtriva)、利匹韦林(强生公司,商品名为Edurant)、Tenofoviral afenamide(简写为TAF,是替诺福韦【商品名Viread】的加强版)的复方药物。这种药物获批治疗12岁及年龄更大患者的I型HIV病毒感染。I型H

吉利德公司HIV联合治疗方法得到FDA批准,这为吉利德公司在该治疗领域取得领袖地位奠定了一块基石。

此次获批的新药,名为Odefsey,是恩曲他滨(商品名Emtriva)、利匹韦林(强生公司,商品名为Edurant)、Tenofoviral afenamide(简写为TAF,是替诺福韦【商品名Viread】的加强版)的复方药物。这种药物获批治疗12岁及年龄更大患者的I型HIV病毒感染。I型HIV也是最常感染的HIV病毒类型。

根据汤森路透的预测,吉利德的这种新药Odefsey有望在2020年达到销售高峰,为16亿美元。这也是第2个通过FDA批准的包括TAF在内的鸡尾酒疗法。第1个是去年11月获批的Genvoya,是TAF、Tybost、Emtriva和Vitekta的复方药物。

吉利德能够如此快速上市,得益于FDA的快速通道,使10个月审批期减少到6个月。吉利德为此付给Knight Therapeutics1.25亿美元。

除了Odefsey,吉利德同时在开发包括TAF和Emtriva的复方药物。汤森路透估计此药的销售高峰为每年20亿美元。

吉利德面临的挑战越来越大。其竞争者包括合作者强生公司、合资企业ViiV Healthcare(葛兰素史克、辉瑞和Shionogi的合资公司)。每个竞争对手都在探寻安全性更高的HIV治疗药物组合,尽力抢占艾滋病治疗领域更大的市场份额。Odefsey顺利获批,为吉利德的霸主地位奠定了基础,在这场竞争中无疑已经取得先手。

原文出处:Gilead's latest HIV cocktail wins FDA approval with a blockbuster pedigree

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    2016-06-21 bugit
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    2016-03-10 qblt
  5. [GetPortalCommentsPageByObjectIdResponse(id=1839409, encodeId=5bb018394099e, content=<a href='/topic/show?id=341ae311ea' target=_blank style='color:#2F92EE;'>#FDA批准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7311, encryptionId=341ae311ea, topicName=FDA批准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=bugit, createdTime=Tue Jun 21 22:08:00 CST 2016, time=2016-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687262, encodeId=cc7a168e2627a, content=<a href='/topic/show?id=df72966659b' target=_blank style='color:#2F92EE;'>#销售#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96665, encryptionId=df72966659b, topicName=销售)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bca28361924, createdName=1249862am81(暂无昵称), createdTime=Wed Aug 17 05:08:00 CST 2016, time=2016-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1542999, encodeId=bc32154299988, content=<a href='/topic/show?id=f187102958c1' target=_blank style='color:#2F92EE;'>#鸡尾酒疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102958, encryptionId=f187102958c1, topicName=鸡尾酒疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b09513514566, createdName=12498768m17(暂无昵称), createdTime=Thu Mar 10 07:08:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574800, encodeId=988c15e4800e5, content=<a href='/topic/show?id=da8110295622' target=_blank style='color:#2F92EE;'>#鸡尾酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102956, encryptionId=da8110295622, topicName=鸡尾酒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=519516025516, createdName=qblt, createdTime=Thu Mar 10 07:08:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68245, encodeId=788668245e3, content=都是利益集团, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Wed Mar 09 08:27:00 CST 2016, time=2016-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68236, encodeId=52fb682369c, content=HIV挣钱,丧心病狂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib260FNcic8ThYZTmbW36JHpvHcnIog7VbWIQjibo1kwuH9obXRJJtqHn1hYHHLG0DpIMIBVFPhBBpQOJWDk1rbib2Y/0, createdBy=d27274268, createdName=sillywu, createdTime=Wed Mar 09 06:06:00 CST 2016, time=2016-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68224, encodeId=2a70682246e, content=愿HIV感染者越来越少,珍爱生命, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Tue Mar 08 22:39:00 CST 2016, time=2016-03-08, status=1, ipAttribution=)]
    2016-03-09 Dr.LV

    都是利益集团

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1839409, encodeId=5bb018394099e, content=<a href='/topic/show?id=341ae311ea' target=_blank style='color:#2F92EE;'>#FDA批准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7311, encryptionId=341ae311ea, topicName=FDA批准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=bugit, createdTime=Tue Jun 21 22:08:00 CST 2016, time=2016-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687262, encodeId=cc7a168e2627a, content=<a href='/topic/show?id=df72966659b' target=_blank style='color:#2F92EE;'>#销售#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96665, encryptionId=df72966659b, topicName=销售)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bca28361924, createdName=1249862am81(暂无昵称), createdTime=Wed Aug 17 05:08:00 CST 2016, time=2016-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1542999, encodeId=bc32154299988, content=<a href='/topic/show?id=f187102958c1' target=_blank style='color:#2F92EE;'>#鸡尾酒疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102958, encryptionId=f187102958c1, topicName=鸡尾酒疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b09513514566, createdName=12498768m17(暂无昵称), createdTime=Thu Mar 10 07:08:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574800, encodeId=988c15e4800e5, content=<a href='/topic/show?id=da8110295622' target=_blank style='color:#2F92EE;'>#鸡尾酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102956, encryptionId=da8110295622, topicName=鸡尾酒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=519516025516, createdName=qblt, createdTime=Thu Mar 10 07:08:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68245, encodeId=788668245e3, content=都是利益集团, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Wed Mar 09 08:27:00 CST 2016, time=2016-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68236, encodeId=52fb682369c, content=HIV挣钱,丧心病狂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib260FNcic8ThYZTmbW36JHpvHcnIog7VbWIQjibo1kwuH9obXRJJtqHn1hYHHLG0DpIMIBVFPhBBpQOJWDk1rbib2Y/0, createdBy=d27274268, createdName=sillywu, createdTime=Wed Mar 09 06:06:00 CST 2016, time=2016-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68224, encodeId=2a70682246e, content=愿HIV感染者越来越少,珍爱生命, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Tue Mar 08 22:39:00 CST 2016, time=2016-03-08, status=1, ipAttribution=)]
    2016-03-09 sillywu

    HIV挣钱,丧心病狂

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1839409, encodeId=5bb018394099e, content=<a href='/topic/show?id=341ae311ea' target=_blank style='color:#2F92EE;'>#FDA批准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7311, encryptionId=341ae311ea, topicName=FDA批准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=bugit, createdTime=Tue Jun 21 22:08:00 CST 2016, time=2016-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687262, encodeId=cc7a168e2627a, content=<a href='/topic/show?id=df72966659b' target=_blank style='color:#2F92EE;'>#销售#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96665, encryptionId=df72966659b, topicName=销售)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bca28361924, createdName=1249862am81(暂无昵称), createdTime=Wed Aug 17 05:08:00 CST 2016, time=2016-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1542999, encodeId=bc32154299988, content=<a href='/topic/show?id=f187102958c1' target=_blank style='color:#2F92EE;'>#鸡尾酒疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102958, encryptionId=f187102958c1, topicName=鸡尾酒疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b09513514566, createdName=12498768m17(暂无昵称), createdTime=Thu Mar 10 07:08:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574800, encodeId=988c15e4800e5, content=<a href='/topic/show?id=da8110295622' target=_blank style='color:#2F92EE;'>#鸡尾酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102956, encryptionId=da8110295622, topicName=鸡尾酒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=519516025516, createdName=qblt, createdTime=Thu Mar 10 07:08:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68245, encodeId=788668245e3, content=都是利益集团, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Wed Mar 09 08:27:00 CST 2016, time=2016-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68236, encodeId=52fb682369c, content=HIV挣钱,丧心病狂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib260FNcic8ThYZTmbW36JHpvHcnIog7VbWIQjibo1kwuH9obXRJJtqHn1hYHHLG0DpIMIBVFPhBBpQOJWDk1rbib2Y/0, createdBy=d27274268, createdName=sillywu, createdTime=Wed Mar 09 06:06:00 CST 2016, time=2016-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68224, encodeId=2a70682246e, content=愿HIV感染者越来越少,珍爱生命, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00531550470, createdName=layyjiangli, createdTime=Tue Mar 08 22:39:00 CST 2016, time=2016-03-08, status=1, ipAttribution=)]
    2016-03-08 layyjiangli

    愿HIV感染者越来越少,珍爱生命

    0

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