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J Periodontal Res:naswardippers的牙周参数及胶原降解生物标志物的释放

2018-04-05 MedSci MedSci原创

本研究的目的是比较naswar(NW)和non-naswar(对照组)的临床牙周参数和牙龈胶原蛋白的C-端肽吡啶啉交联(ICTP)和C端交联端肽(CTX)控制)释放。

本研究的目的是比较naswar(NW)和non-naswar(对照组)的临床牙周参数和牙龈胶原蛋白的C-端肽吡啶啉交联(ICTP)和C端交联端肽(CTX)释放。

实验纳入87名个体(42名NW和45名对照)。在NW和对照组之间比较临床(菌斑指数,探查出血,探诊深度和临床附着丧失)和影像学(边缘骨吸收)牙周参数。取NW和对照组受试者的龈标本,评估ICTP和CTX水平(使用ELISA)并使用微拉曼光谱分析。使用Kruskal-Wallis和Mann-Whitney U检验评估组间牙周参数差异的显着性。使用配对t检验来比较所有组的暴露时间的干质量损失百分比和ICTP和CTX的释放速率,以检查暴露时间的影响。

结果:NW组的临床和影像学牙周参数显着高于对照组(P <0.01)。在拉曼光谱中,NW组中最强和最锐的频带出现在1260cm-1处。在Amide I的拉曼频带观察到波数略有变化。 NW组患者的ICTP和CTX释放率显着高于对照组(P <0.05)。组类型和时间均ICTP和CTX的释放有显着影响(P <0.05)。

结论: NW组受试者的临床和放射学牙周参数差于对照组。由于使用NW,NW组受试者结缔组织中的胶原蛋白分解程度更高。

原始出处:

U. Daood, et al. Clinical and radiographic periodontal parameters and release of collagen degradation biomarkers in naswardippers. Journal of Periodontal Research. 2018 February. doi:10.1111/jre.12496

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    2018-08-27 一叶知秋
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    2018-04-06 feather89
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  8. [GetPortalCommentsPageByObjectIdResponse(id=1878263, encodeId=bcb418e8263c2, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Mon Aug 27 18:33:00 CST 2018, time=2018-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727225, encodeId=f09b1e2722528, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Apr 06 13:33:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1949438, encodeId=d12219494385f, content=<a href='/topic/show?id=16d16e5034c' target=_blank style='color:#2F92EE;'>#牙周参数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67503, encryptionId=16d16e5034c, topicName=牙周参数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Fri Oct 19 19:33:00 CST 2018, time=2018-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450855, encodeId=f6ef1450855b7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Apr 07 01:33:00 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560726, encodeId=165c1560e26a5, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Sat Apr 07 01:33:00 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566735, encodeId=6c3a1566e353c, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Sat Apr 07 01:33:00 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1841214, encodeId=a1e11841214ad, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Fri Feb 15 07:33:00 CST 2019, time=2019-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303186, encodeId=e426303186f3, content=认真学习.不断进步.把经验分享给同好.点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Fri Apr 06 06:47:16 CST 2018, time=2018-04-06, status=1, ipAttribution=)]
    2018-04-06 lietome2

    认真学习.不断进步.把经验分享给同好.点赞了!

    0

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