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DIABETOLOGIA:2006年至2015年期间苏格兰2型糖尿病患者急性心肌梗死,心绞痛和冠状动脉血运重建的发病率和病死率趋势

2019-04-03 不详 网络

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该研究的目的是调查2006年至2015年期间苏格兰2糖尿病患者和非糖尿病患者的急性心肌梗死AMI)发生率和病例死亡率以及心绞痛和冠状动脉血管重建术的入院趋势。

在这项回顾性队列研究中,从成人入院和与基于人群的糖尿病登记相关的死亡记录中获得AMI,心绞痛和血运重建事件数据。根据年龄,性别,剥夺和日历年调整或分层的负二项模型估计糖尿病状况的发病率。Logistic回归用于估计糖尿病状态的AMI病例死亡率。

结果显示,在3490万人年的随访期间,共发生129,926AMI事件,41,263例心绞痛入院和69,875例冠状动脉血运重建术。AMI,心绞痛和血运重建术的调整发生率每年分别下降了2.0%(95CI 1.73%,2.26%),9.62%(95CI 9.22%,10.01%)和0.35%(95CI -0.09%,0.79%) )。糖尿病状况的下降率没有显著差异。AMI治疗2型糖尿病的男性患者为1.8695CI 1.74,1.98),女性为2.3295CI 2.15,2.51)。在第一次急性心肌梗死住院的77,211人中,有7842人(10.2%)在入院后30天内死亡。2型糖尿病患者的病死率高于非糖尿病患者,两组患者死亡率均下降7.93%(95CI 7.03%,8.82%)。

研究表明,AMI,心绞痛,血运重建和AMI病例死亡率随着时间的推移而下降,但与2型糖尿病相关的风险增加几乎保持不变。

原始出处:

Stephanie H. ReadColin M. FischbacherTrends in incidence and case fatality of acute myocardial infarction, angina and coronary revascularisation in people with and without type 2 diabetes in Scotland between 2006 and 2015

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    2019-04-03 misszhang

    谢谢MedSci提供最新的资讯

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