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Diabetologia:研究证实抗氧化剂丰富的食品可以极大降低糖尿病风险!

2017-11-10 佚名 medicalxpress

在食用富含抗氧化剂食物的个体中观察到2型糖尿病的风险较低。这一效应主要由水果,蔬菜,茶叶和其他热饮料以及适量的酒精消耗所贡献,最近Inserm研究小组在“糖尿病研究”杂志上报道了该研究。

在食用富含抗氧化剂食物的个体中观察到2型糖尿病的风险较低。这一效应主要由水果,蔬菜,茶叶和其他热饮料以及适量的酒精消耗所贡献,最近Inserm研究小组在“糖尿病研究”杂志上报道了该研究。

先前已经将富含水果和蔬菜的饮食与某些癌症和心血管疾病的风险降低联系起来。 Inserm研究小组(法国维勒瑞夫流行病学和人口健康研究中心)已经证明,这种饮食与降低2型糖尿病风险相似。

该研究小组已经怀疑,在以前的研究的基础上可能存在一些联系,表明某些抗氧化剂,如维生素C和E,类固醇或类黄酮,与降低2型糖尿病风险有关。然而,这些研究只看到孤立的营养素,而不是在饮食的总抗氧化能力。因此,研究人员想要根据其抗氧化能力来验证整体饮食是否与糖尿病风险有关。使用来自1990年招募的法国女性的E3N队列中的数据,年龄在40-65岁之间,他们跟踪了从1993年到2008年的64223名女性,这些女性在纳入本研究时均没有糖尿病和心血管疾病。每位参与者在研究开始时都完成了饮食调查问卷,包括200多种不同食物的详细信息。 Inserm的研究人员利用这些信息和一个提供大量不同食物的抗氧化能力的意大利数据库计算了每个参与者的“总膳食抗氧化能力”得分。然后该小组分析了这个评分与随访期间糖尿病发生风险之间的关系。

结果显示,随着抗氧化剂消耗增加至15mmol /天,糖尿病风险降低,高于此水平达到平台。通过食用富含抗氧化剂的食物,如黑巧克力,茶,核桃,李子,蓝莓,草莓或榛子等,可以使膳食中的抗氧化剂达到这个水平。抗氧化评分最高的女性患糖尿病的风险降低了27%,而得分最低的糖尿病风险则降低了27%。 “考虑到所有其他主要糖尿病风险因素:吸烟,教育水平,高血压,高胆固醇水平,糖尿病家族史以及最重要的BMI(最重要的因素)之后,这种联系仍然存在”,本研究的第一作者Francesca Romana Mancini澄清道。对高饮食抗氧化评分贡献最大的食物是水果和蔬菜,茶和红酒(消耗量适中)。尽管抗氧化剂含量很高,作者排除了咖啡分析的原因,因为咖啡中的抗氧化剂已被证明与降低2型糖尿病风险有关,因此可能会掩盖来自其他来源的抗氧化剂的影响。

E3N研究的负责糖尿病研究的首席研究员Guy Fagherazzi解释说:“这项工作补充了我们目前对孤立食物和营养物质作用的认识,并提供了食物与2型糖尿病之间关系的更全面的观点。 “我们已经表明,增加摄入抗氧化剂可以有助于降低糖尿病风险”。这就提出了一个问题:为什么我们知道这些分子抵消了对细胞有害的自由基的作用,但除此之外,还可能有更具体的作用,例如对胰岛素细胞敏感性的影响。这将需要在未来的研究中得到证实,”Francesca Romana Mancini总结道。

原始出处:

Francesca Romana ManciniAurélie AffretCourtney Dow, et.al. Dietary antioxidant capacity and risk of type 2 diabetes in the large prospective E3N-EPIC cohort. Diabetologia

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    2017-11-13 lou.minghong

    学习了谢谢分享!

    0

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近日,浙江大学医学院免疫学研究所鲁林荣教授课题组则从免疫学角度发现了抗氧化剂的“副作用”,他们最新研究提示,补充摄入抗氧化剂存在促进自身性免疫疾病的发生发展的风险。成果文章4月12日发表在免疫学着名期刊《实验医学杂志》上。 广告中抗氧化剂常常是延缓衰老、青春永驻的代名词。但事实并非如此,已有研究显示,对于肿瘤患者,抗氧化剂能促进肿瘤的生长和转移。近日,浙江大学医学院免疫学研究所鲁林荣教授课题组则

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对许多人来说,随着年龄增长,皮肤健康状况越来越差是最让人讨厌的一件事情。随着我们年龄日益增长,我们的皮肤逐渐失去弹性,变薄变干,修复能力下降。然而,一项最新研究发现了一种抗氧化剂能够延缓皮肤衰老。

Sci Rep:这种廉价安全的抗氧化剂能延缓皮肤衰老

许多抗衰老的护肤品中都含有抗氧化成分。近日,来自马里兰大学(UMD)的一项新研究表明,一种常用廉价又安全的抗氧化剂——亚甲基蓝可以减缓人体皮肤衰老。研究人员发现,在培养的人类皮肤细胞和模拟皮肤组织中测试时,亚甲基蓝可以减缓或逆转几种衰老迹象。该研究于2017年5月30日在Scientific Reports杂志上发表。UMD的细胞生物学和分子遗传学副教授Kan Cao说:“我们的工作表明,亚甲基蓝

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