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J hypertens:膳食钠限制对动脉硬度的影响!

2017-10-31 xing.T MedSci原创

由此可见,这项荟萃分析的结果表明饮食钠摄入量的限制可降低了动脉硬度,这种效应至少部分独立于血压的变化。

动脉硬化是心血管疾病的独立危险因素,钠摄入量可能是动脉硬度的决定因素。然而,有关减少膳食钠摄入量对动脉硬度影响的研究得到了不一致的结果。因此,研究人员对盐分限制和动脉硬度的随机对照试验进行了一项系统评价和荟萃分析,以得出更明确的结论。

研究人员系统地检索了可用的在线数据库(从1996年到2017年7月),纳入了报道了由颈动脉 - 股动脉脉搏波速度(PWV)来评估动脉硬度的随机对照试验。对于每项研究,研究人员使用随机效应模型合并了平均差异和95%可信区间。同时,研究人员进行了敏感性、异质性、出版偏倚、亚组和荟萃回归分析。

该荟萃分析共有11项研究符合预先定义的入选标准,提供了14个研究队列,431名参与者,干预时间为1-6周。在汇总分析中,平均钠摄入量减少89.3mmol/d与PWV下降2.84%(95%可信区间为:0.51-5.08)相关。这些研究没有显著的异质性,没有发现到出版偏倚的证据。这些纳入分析研究的单一特征似乎并不影响盐分对PWV的影响。

由此可见,这项荟萃分析的结果表明饮食钠摄入量的限制可降低了动脉硬度,这种效应至少部分独立于血压的变化。

原始出处:

Elia, Lanfranco, et al. Effect of dietary sodium restriction on arterial stiffness: systematic review and meta-analysis of the randomized controlled trials.J hypertens.2017.http://journals.lww.com/jhypertension/Abstract/publishahead/Effect_of_dietary_sodium_restriction_on_arterial.97584.aspx

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    2018-05-10 feather89
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    2018-04-08 howi
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    2017-11-06 wxl882001

    学习一下

    0

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    2017-11-02 zhaojie88
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    2017-10-31 1e127dd4m40(暂无匿称)

    学习了

    0

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    2017-10-31 有备才能无患

    动脉硬化是心血管疾病的独立危险因素.钠摄入量可能是动脉硬度的决定因素.然而.有关减少膳食钠摄入量对动脉硬度影响的研究得到了不一致的结果

    0

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