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Alzheimers Dementia:随访2万人20年,痴呆诊断前后,医疗开支情况如何?

2022-03-15 Freeman MedSci原创

早在正式诊断痴呆症前10年就出现了超额的医疗费用

目前,痴呆症是导致死亡和残疾的主要原因之一,给痴呆症疾病(以下简称 "痴呆症")患者、其家人和社会带来了巨大的负担。由于65岁以后患痴呆症的风险每5年翻一番,而且许多国家的老年人口在不断增长,因此患病率和相关的医疗费用也可能在加速增长。2018年,全世界估计有>5000万痴呆症患者,预计到2050年,这一数字将上升到>1.52亿。

随着痴呆症发病率的上升,政策越来越有动力去考虑经济学家的观点,并更准确地考虑是什么在驱动成本。决策者需要可靠的、最新的、关于痴呆症后果的信息来规划服务和制定适当的政策。此外,了解解释痴呆症这些后果的基本因素也有助于确定和评估具体的干预方案。

据估计,全球每年的痴呆症成本为1万亿美元。对医疗费用的分析可以提供与特定疾病相关的护理负担的来源和程度的有用信息。有几项研究估计了不同国家环境下的痴呆症成本。例如,最近对26项研究的系统回顾估计,欧洲和美国的痴呆症患者每人每年的成本分别为32,507欧元和43,899欧元(2015价格年)。

然而,许多研究都缺乏对比组--即认知健康的人群,因此很难衡量痴呆症的超额医疗费用。此外,审查中的大多数研究都是基于横断面数据,没有提供关于痴呆症费用随时间发展的信息。

藉此,瑞典隆德大学的Sofie Persson等人, 探究了17年内归因于痴呆症的医疗费用,并提供诊断前十年的费用洞察,估计诊断时费用的增加程度,并检查诊断后6年的费用发展趋势。由于以前的研究表明,痴呆症的认知障碍可能在诊断前18年就已经形成。

核心假设是,在痴呆症正式诊断前几年就可以观察到医疗费用的增加。

他们利用瑞典南部被诊断为痴呆症患者(2010-2016年)的行政登记数据(n = 21,184),以及一个没有痴呆症的对比组,使用纵向回归分析对17年的医疗费用进行了研究。

他们发现:痴呆组每人每年的平均医疗费用在诊断前一直较高(10年前,瑞典克朗(SEK)2063,P < .005;1年前。SEK8166,P < .005)。

在诊断时,保健费用是其两倍多(44,410瑞典克朗,P < .005)。

诊断后4至6年,与比较者相比,费用没有明显差异。

该研究的重要意义在于发现了:早在正式诊断痴呆症前10年就出现了超额的医疗费用,虽然诊断后费用激增,但4年后的医疗费用并无不同。这些发现对目前公认的痴呆症成本假设提出质疑。


原文出处:
Persson S, Saha S, Gerdtham U, Toresson H, Trépel D, Jarl J. Healthcare costs of dementia diseases before, during and after diagnosis: Longitudinal analysis of 17 years of Swedish register data. Alzheimer’s & Dementia. Published online February 21, 2022:alz.12619. doi:10.1002/alz.12619

 

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    2022-12-10 anminleiryan
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    2022-03-15 梅斯助教

    随访

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1718131, encodeId=12521e18131cf, content=<a href='/topic/show?id=8f0658433a' target=_blank style='color:#2F92EE;'>#dementia#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5843, encryptionId=8f0658433a, topicName=dementia)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307e32501717, createdName=linlin2323, createdTime=Fri Oct 14 07:53:15 CST 2022, time=2022-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779829, encodeId=cb431e798290a, content=<a href='/topic/show?id=51b4238909' target=_blank style='color:#2F92EE;'>#alzheimers#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2389, encryptionId=51b4238909, topicName=alzheimers)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Fri Nov 18 06:53:15 CST 2022, time=2022-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1878490, encodeId=d5bb18e849020, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Sat Dec 10 19:53:15 CST 2022, time=2022-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1202707, encodeId=ddc01202e078b, content=随访, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/ddebdec707734c8390a07bd0c1048717/cc11caf5d607430e9f4ca556fed68ab1.jpg, createdBy=2c4d5497888, createdName=梅斯助教, createdTime=Tue Mar 15 10:51:53 CST 2022, time=2022-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1202705, encodeId=b9d61202e05ec, content=<a href='/topic/show?id=1ff01043052c' target=_blank style='color:#2F92EE;'>#谢谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104305, encryptionId=1ff01043052c, topicName=谢谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/ddebdec707734c8390a07bd0c1048717/cc11caf5d607430e9f4ca556fed68ab1.jpg, createdBy=2c4d5497888, createdName=梅斯助教, createdTime=Tue Mar 15 10:51:09 CST 2022, time=2022-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1338551, encodeId=3bce1338551f2, content=<a href='/topic/show?id=767711566a9' target=_blank style='color:#2F92EE;'>#MERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11566, encryptionId=767711566a9, topicName=MERS)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/71tKRib0PibveVjnEa7tPLMaCzoKicFlKSEOzRTGf4wNvDV54kJyNx1ott1D5Xp5gRu7IwUia77oN0YFdffvQMu6Ug/132, createdBy=9e302500146, createdName=ms49895894946433513521, createdTime=Fri Mar 11 08:53:15 CST 2022, time=2022-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1246675, encodeId=822612466e5da, content=老年性痴呆,未来还是希望借助神经电生理吧,也许更为有效!, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=neuro.Dr, createdTime=Wed Mar 09 20:53:15 CST 2022, time=2022-03-09, status=1, ipAttribution=)]
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    2022-03-09 neuro.Dr

    老年性痴呆,未来还是希望借助神经电生理吧,也许更为有效!

    0

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