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Lancet Infect Dis:警告!艾滋病毒耐药性正在不断攀升,是否会导致HIV大流行?

2017-12-01 佚名 medicalxpress

发表在《柳叶刀》上的一份最新研究中,科学家们研究了开始接受抗逆转录病毒治疗的数据,发现人们对非核苷类逆转录酶抑制剂的抗药性越来越多,那些发现对于全球艾滋病的防治工作起到警告的作用。

发表在《柳叶刀》上的一份最新研究中,科学家们研究了开始接受抗逆转录病毒治疗的数据,发现人们对非核苷类逆转录酶抑制剂的抗药性越来越多,那些发现对于全球艾滋病的防治工作起到警告的作用。

近年来,艾滋病毒治疗方法有了很大改善,全世界近2100万人正在接受抗逆转录病毒疗法。然而,艾滋病作为一种公共健康威胁,为了终止艾滋病的流行,尽量减少耐药性将是应对措施的一部分。我们的研究结果表明,提高监测耐药性的重要性,并建议我们应审查列入一线治疗的药物。

研究人员汇集了358个数据集,其中包括来自63个中低收入国家的56044名成年人的数据,他们从1996和2016开始对艾滋病毒进行一线治疗。这项研究是由五大洲的33位研究人员共同组成的。

目前的一线治疗是非核苷类逆转录酶抑制剂(NNRTI)与核苷逆转录酶抑制剂(NRTI)的组合。研究小组专注于研究包括对病毒耐药突变的数据。该研究团队发现,从2001年-2016年,在中等收入的国家,包括撒哈拉以南非洲,拉丁美洲和亚洲耐药性的问题呈上涨趋势。研究小组发现耐药性最高的出现在南部非洲。

研究小组还发现,以前使用抗逆转录病毒药物的人更容易携带抗药性病毒,并且有更大的病毒学失败风险,也就是说,艾滋病毒治疗不会充分控制病毒的风险。

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    2018-08-07 howi
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    2017-12-07 半夏微凉

    学习了谢谢分享

    0

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    2017-12-02 1dd8c52fm63(暂无匿称)

    学习学习.了解了解

    0

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    2017-12-02 1209e435m98(暂无昵称)

    学习了.谢谢分享!

    0

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    2017-12-01 惠映实验室

    病毒也耐药.变异性太强大了

    0

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    2017-12-01 Y—xianghai

    学习了新知识

    0

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