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拜耳斥资40亿美元收购基因治疗公司AskBio

2020-10-26 MedSci原创 MedSci原创

AskBio的腺相关基因(AAV)治疗平台已在多种疾病中显示出潜力,包括庞贝病、帕金森病和充血性心力衰竭。

拜耳宣布斥资40亿美元收购基因治疗公司Asklepios BioPharmaceutical(AskBio),以增强其在细胞和基因治疗管线。

Jobs with Asklepios BioPharmaceutical, Inc. (AskBio)

拜耳公司将首先预付款20亿美元,以获得对AskBio基因治疗平台。除了预付款外,拜耳还将根据里程碑额外支付高达20亿美元。拜耳在今天发布的一份声明表示,预计潜在里程碑付款中的75%将在未来五年内完成。

AskBio的腺相关基因(AAV)治疗平台已在多种疾病中显示出潜力,该公司的主要研究计划专注于庞贝病、帕金森病和充血性心力衰竭。自2001年成立以来,该公司已经开发了数百个专有的第三代AAV衣壳和启动子,用于改善功效、免疫应答以及组织和器官特异性。

AAV

图片来源:AskBio

该公司的联合创始人Jude Samulski是基因疗法的先驱,他还创建了两个AskBio子公司,Bamboo Therapeutics和Chatham Therapeutics,分别专注于杜氏肌营养不良症和血友病。

原始出处:

http://www.pmlive.com/pharma_news/bayer_pays_an_initial_$2bn_for_gene_therapy_firm_askbio_1354772

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    2021-08-08 sunylz
  2. [GetPortalCommentsPageByObjectIdResponse(id=1919158, encodeId=53071919158b2, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sun Aug 08 12:01:02 CST 2021, time=2021-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1318502, encodeId=11a7131850264, content=<a href='/topic/show?id=9a535625968' target=_blank style='color:#2F92EE;'>#拜耳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56259, encryptionId=9a535625968, topicName=拜耳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11b4465, createdName=ying_wu, createdTime=Wed Oct 28 14:01:02 CST 2020, time=2020-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894933, encodeId=1592894933bb, content=学习了很不错<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/31/e28d0566f86de2a159e1850018623a0d.jpg, createdBy=62d75176163, createdName=小天要好好生活, createdTime=Tue Oct 27 21:09:40 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894730, encodeId=db38894e30e7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200827/23619d3c1e944e23a9350a54edbacb81/d195c15802ae49df9886c39d3dcf868e.jpg, createdBy=e4295413629, createdName=ms3000000956234844, createdTime=Tue Oct 27 10:02:13 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894687, encodeId=574a89468e7d, content=希望看到更多好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00074131254, createdName=13c30453m58暂无昵称, createdTime=Tue Oct 27 06:02:01 CST 2020, time=2020-10-27, status=1, ipAttribution=)]
    2020-10-28 ying_wu
  3. [GetPortalCommentsPageByObjectIdResponse(id=1919158, encodeId=53071919158b2, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sun Aug 08 12:01:02 CST 2021, time=2021-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1318502, encodeId=11a7131850264, content=<a href='/topic/show?id=9a535625968' target=_blank style='color:#2F92EE;'>#拜耳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56259, encryptionId=9a535625968, topicName=拜耳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11b4465, createdName=ying_wu, createdTime=Wed Oct 28 14:01:02 CST 2020, time=2020-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894933, encodeId=1592894933bb, content=学习了很不错<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/31/e28d0566f86de2a159e1850018623a0d.jpg, createdBy=62d75176163, createdName=小天要好好生活, createdTime=Tue Oct 27 21:09:40 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894730, encodeId=db38894e30e7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=182, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200827/23619d3c1e944e23a9350a54edbacb81/d195c15802ae49df9886c39d3dcf868e.jpg, createdBy=e4295413629, createdName=ms3000000956234844, createdTime=Tue Oct 27 10:02:13 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894687, encodeId=574a89468e7d, content=希望看到更多好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00074131254, createdName=13c30453m58暂无昵称, createdTime=Tue Oct 27 06:02:01 CST 2020, time=2020-10-27, status=1, ipAttribution=)]
    2020-10-27 小天要好好生活

    学习了很不错#学习#

    0

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    2020-10-27 ms3000000956234844

    学习了

    0

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    2020-10-27 13c30453m58暂无昵称

    希望看到更多好药

    0

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