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每周禁食2天,对2型糖尿病患者有好处!喝无糖饮料可降低结肠癌死亡风险?

2018-08-08 文韬 牛艳红 秦苗 医师报

每周禁食2天 降糖减肥效果堪比每天饮食控制 来自南澳大学的一项研究发现,对于2型糖尿病患者,与持续每天饮食控制相比,每周禁食2 d在降低糖化血红蛋白(HbA1c)方面效果相当,而且有助于减轻体重。(JAMA Network Open. 7月20日在线版)


每周禁食2天 降糖减肥效果堪比每天饮食控制

来自南澳大学的一项研究发现,对于2型糖尿病患者,与持续每天饮食控制相比,每周禁食2 d在降低糖化血红蛋白(HbA1c)方面效果相当,而且有助于减轻体重。(JAMA Network Open. 7月20日在线版)

研究者表示,间歇性禁食可能是糖尿病患者的一种有效替代饮食控制策略。但对于使用磺脲类药物和(或)胰岛素的患者,间歇性禁食需要调整药物和常规监测,特别是在开始阶段,因此应谨慎使用。

研究纳入137例BMI≥27 kg/m2的2型糖尿病成人患者,平均年龄为61岁,平均HbA1c为7.3%,平均BMI为36 kg/m2。禁食至每天摄入的热量控制在500~600cal;持续饮食控制组每天摄入的热量控制在1200~1500 cal。

结果显示,在12个月时,持续饮食控制组与间歇性禁食组HbA1c变化相似,分别降低0.5%与0.3%。两组体重变化也相似,分别降低5 kg和6.8 kg。两组在走路步数、空腹血糖、血脂和药物剂量变化方面也没有显著差异。另外,两组低血糖事件发生率也相当。

体重正常的中心性肥胖者 血管风险也增加

据2018年美国预防心脏病学会大会上公布的一项研究显示,与无中心性肥胖者(无论BMI是否正常)相比,体重正常但有中心性肥胖者的血管风险增加。(源自Healio)

研究纳入1692例患者,其中48%为男性,平均年龄为61岁。中心性肥胖根据腰臂比(女性≥0.85,男性≥0.9)确定。中位随访16.1年,22.6%的患者发生严重心血管事件,包括心梗93例、介入治疗32例、冠脉旁路移植术25例、全因死亡66例和卒中129例。

分析显示,体重正常的中心性肥胖患者主要不良心血管事件风险增加79%,校正年龄、性别后,该关联仍存在(HR=1.87)。进一步校正糖尿病、高血压和血脂异常后,关联性减弱,但仍有统计学意义(HR=1.52)。

喝无糖饮料降低结肠癌死亡风险?

近日,耶鲁大学癌症中心发表研究称,喝“无糖”软饮料有助于降低晚期结肠癌患者癌症复发和死亡的风险。(PLOS One.7月19日在线版)

这项试验是CALGB 89803试验的一部分。该试验研究Ⅲ期结肠癌的辅助治疗,所有患者在治疗中途(手术后4个月)和治疗结束后6个月(手术后14个月)完成了关于饮食和生活习惯的自填式问卷。

这项队列研究最终纳入1018例患者,中位随访7.3年,348例患者出现结肠癌复发或新发原发性肿瘤,其中有265例死亡。

结果表明,患有Ⅲ期结肠癌的患者,每天饮用1份(300 ml)或以上的人造甜味剂饮料,死亡或复发的风险降低了46%。

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1255787, encodeId=1cf51255e8749, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383468, encodeId=b3761383468aa, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474565, encodeId=765814e45656d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554662, encodeId=960315546623e, content=<a href='/topic/show?id=4a70591102d' target=_blank style='color:#2F92EE;'>#无糖饮料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59110, encryptionId=4a70591102d, topicName=无糖饮料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23214540780, createdName=guojianrong, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1041768, encodeId=0d571041e68cf, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Aug 08 23:20:00 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337385, encodeId=c21433e385a7, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Aug 08 22:31:42 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337362, encodeId=8cc733e362b5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Wed Aug 08 21:33:35 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-08 misszhang

    谢谢MedSci提供最新的资讯

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1255787, encodeId=1cf51255e8749, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383468, encodeId=b3761383468aa, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474565, encodeId=765814e45656d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554662, encodeId=960315546623e, content=<a href='/topic/show?id=4a70591102d' target=_blank style='color:#2F92EE;'>#无糖饮料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59110, encryptionId=4a70591102d, topicName=无糖饮料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23214540780, createdName=guojianrong, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1041768, encodeId=0d571041e68cf, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Aug 08 23:20:00 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337385, encodeId=c21433e385a7, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Aug 08 22:31:42 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337362, encodeId=8cc733e362b5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Wed Aug 08 21:33:35 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-08 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1255787, encodeId=1cf51255e8749, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383468, encodeId=b3761383468aa, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474565, encodeId=765814e45656d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554662, encodeId=960315546623e, content=<a href='/topic/show?id=4a70591102d' target=_blank style='color:#2F92EE;'>#无糖饮料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59110, encryptionId=4a70591102d, topicName=无糖饮料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23214540780, createdName=guojianrong, createdTime=Fri Aug 10 11:20:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1041768, encodeId=0d571041e68cf, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Aug 08 23:20:00 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337385, encodeId=c21433e385a7, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Aug 08 22:31:42 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337362, encodeId=8cc733e362b5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Wed Aug 08 21:33:35 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-08 医者仁心5538

    学习了

    0

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