Baidu
map

JAHA:冠状动脉疾病与射血分数正常的心衰的关系

2022-08-27 MedSci原创 MedSci原创

在对人口统计资料和常见合并征进行调整后,冠心病是HFpEF发生的一个重要危险因素。

射血分数正常的心衰(HFpEF)是一个主要的公共卫生问题,其患病率随着人口老龄化而上升。冠状动脉疾病(CAD)是否为射血分数正常的心衰(HFpEF)患者重要危险因素尚未明确。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,在9902名参与社区动脉粥样硬化风险(ARIC)研究的参与者中,研究人员评估了冠心病与随后发生的HFpEF(左心室射血分数≥50%)和HFrEF(左心室射血分数<50%),研究人员使用具有时间更新变量的生存模型。研究人员还评估了超声心动图在冠心病和HFpEF发病之间的相关性。

在13年的随访中,892名参与者发生冠心病,178人随后发生HF(86人为HFrEF,71人为HFpEF)。冠心病事件发生早期HFrEF和HFpEF发生风险均最大。在CAD事件发生1年以后,调整后的HFrEF和HFpEF发生率相似(每1000人年分别为7.2[95%CI为5.2-10.0]和6.7[4.8-9.2]),且CAD对两者仍具有预测性(HFrEF:风险比为2.76[95%CI为1.99-3.84];HFpEF:风险比为1.85[1.35-2.54])。

在第5次随访(2011-2013)的4779名无HF患者中,490名冠心病患者的左室射血分数较低,左室质量指数、E/E′和左房容积指数较高(均P<0.01)。经过超声心动图测量调整后,CAD患病率与随访5后HFpEF发生率的相关性并不显著,左室舒张功能衰减最大。

由此可见,在对人口统计资料和常见合并征进行调整后,冠心病是HFpEF发生的一个重要危险因素。这种关系部分归因于超声心动图结果的改变,特别是左室舒张功能的改变。

原始出处:

Jenine E. John.et al.Coronary Artery Disease and Heart Failure With Preserved Ejection Fraction: The ARIC Study.JAHA.2022.https://www.ahajournals.org/doi/full/10.1161/JAHA.121.021660

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1994323, encodeId=fa461994323f3, content=<a href='/topic/show?id=b67646808b9' target=_blank style='color:#2F92EE;'>#射血分数正常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46808, encryptionId=b67646808b9, topicName=射血分数正常)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Sat Mar 18 19:04:44 CST 2023, time=2023-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252973, encodeId=a8fd12529e311, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268890, encodeId=850c12688907e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446669, encodeId=125114466696a, content=<a href='/topic/show?id=26b9468137a' target=_blank style='color:#2F92EE;'>#射血分数正常的心衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46813, encryptionId=26b9468137a, topicName=射血分数正常的心衰)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=13435269915, createdName=bugit, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1994323, encodeId=fa461994323f3, content=<a href='/topic/show?id=b67646808b9' target=_blank style='color:#2F92EE;'>#射血分数正常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46808, encryptionId=b67646808b9, topicName=射血分数正常)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Sat Mar 18 19:04:44 CST 2023, time=2023-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252973, encodeId=a8fd12529e311, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268890, encodeId=850c12688907e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446669, encodeId=125114466696a, content=<a href='/topic/show?id=26b9468137a' target=_blank style='color:#2F92EE;'>#射血分数正常的心衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46813, encryptionId=26b9468137a, topicName=射血分数正常的心衰)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=13435269915, createdName=bugit, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1994323, encodeId=fa461994323f3, content=<a href='/topic/show?id=b67646808b9' target=_blank style='color:#2F92EE;'>#射血分数正常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46808, encryptionId=b67646808b9, topicName=射血分数正常)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Sat Mar 18 19:04:44 CST 2023, time=2023-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252973, encodeId=a8fd12529e311, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268890, encodeId=850c12688907e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446669, encodeId=125114466696a, content=<a href='/topic/show?id=26b9468137a' target=_blank style='color:#2F92EE;'>#射血分数正常的心衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46813, encryptionId=26b9468137a, topicName=射血分数正常的心衰)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=13435269915, createdName=bugit, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=)]
    2022-08-28 zhaohui6731
  4. [GetPortalCommentsPageByObjectIdResponse(id=1994323, encodeId=fa461994323f3, content=<a href='/topic/show?id=b67646808b9' target=_blank style='color:#2F92EE;'>#射血分数正常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46808, encryptionId=b67646808b9, topicName=射血分数正常)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Sat Mar 18 19:04:44 CST 2023, time=2023-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252973, encodeId=a8fd12529e311, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268890, encodeId=850c12688907e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446669, encodeId=125114466696a, content=<a href='/topic/show?id=26b9468137a' target=_blank style='color:#2F92EE;'>#射血分数正常的心衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46813, encryptionId=26b9468137a, topicName=射血分数正常的心衰)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=13435269915, createdName=bugit, createdTime=Sun Aug 28 14:04:44 CST 2022, time=2022-08-28, status=1, ipAttribution=)]

相关资讯

A&R:系统性硬化症的舒张功能障碍:危险因素和对死亡率的影响

舒张功能障碍与系统性硬化症(SSc)患者死亡风险增加独立相关。应在SSc患者中解决潜在可改变的风险因素,包括冠状动脉疾病和肥胖以降低死亡风险。

Cardiovasc Diabetol:甘油三酯-葡萄糖指数与普通人心血管疾病及死亡风险的相关性

较高的 TyG 指数可能与普通人群的冠状动脉疾病、心肌梗死和心血管疾病的发病率增加有关

European Radiology:功能CAD-RADS在冠状动脉疾病患者治疗和预后中的价值

冠状动脉CT血管造影(CCTA)是对稳定期胸痛和疑似冠状动脉疾病(CAD)患者进行诊断和治疗计划的一种有效的无创性检查。

Arthritis Rheumatol:类风湿关节炎与冠状动脉疾病和卒中风险的遗传易感性

该研究发现类风湿性关节炎的遗传倾向与冠心病和脑出血的风险增加相关,而这可能是由CRP介导的。应积极监测和管理类风湿性关节炎患者升高的心血管风险,这可能包括抑制全身炎症。

中国50万人研究:每多吃2两粗粮,糖尿病与中风风险分别下降14%和13%!so easy!

J Nutr.:粗粮摄入量与心脏代谢疾病风险:一项中国成年人的前瞻性队列研究

JAMA Cardiol:高密度脂蛋白胆固醇水平过高,冠状动脉疾病患者死亡风险增加

非常高的HDL-C水平与冠状动脉疾病患者较高的死亡风险相关

Baidu
map
Baidu
map
Baidu
map