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JCLA:女性2型糖尿病患者红细胞平均寿命缩短

2019-07-12 不详 网络

众所周知,高血糖状态会缩短红细胞的寿命。红细胞肌酸(EC)反映红细胞平均年龄,可作为溶血指标。在此,我们研究了EC与非糖尿病患者和糖尿病患者的血糖控制指标[糖化血红蛋白或糖化白蛋白(GA)]之间的关系。 本研究包括119名2型糖尿病(T2DM)患者和76名非糖尿病患者(按性别和年龄进行匹配)。我们研究了2型糖尿病和非糖尿病患者中EC和糖化血红蛋白(HbA1c)或GA之间的关系。 研究发

众所周知,高血糖状态会缩短红细胞的寿命。红细胞肌酸(EC)反映红细胞平均年龄,可作为溶血指标。在此,我们研究了EC与非糖尿病患者和糖尿病患者的血糖控制指标[糖化血红蛋白或糖化白蛋白(GA)]之间的关系。

本研究包括1192糖尿病(T2DM)患者和76名非糖尿病患者(按性别和年龄进行匹配)。我们研究了2型糖尿病和非糖尿病患者中EC和糖化血红蛋白(HbA1c)GA之间的关系。

研究发现,红细胞在T2DM病人中肌酸显著高于非糖尿病应承担的主题,EC含量高的比率(> 1.8μmol / g Hb)2型糖尿病患者也显著提高。此外,女性EC明显高于男性EC,且女性EC水平高的比例也明显高于男性EC水平。男性EC与糖化血红蛋白(HbA1c)GA无显著相关,女性EC与两者均有显著正相关。男性2型糖尿病患者与非糖尿病患者的EC无显著差异,而女性2型糖尿病患者的EC明显高于非糖尿病患者。

女性2型糖尿病患者EC与糖化血红蛋白、GA呈显著正相关,提示血糖控制不良的女性糖尿病患者红细胞平均寿命下降。

原始出处:

Masafumi Koga,  Shinya Inada,Shortened mean erythrocyte age in female patients with type 2 diabetes mellitus

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    2020-03-06 jyzxjiangqin

    女性2型糖尿病患者的治疗。

    0

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    2019-09-11 jyzxjiangqin

    女性2型糖尿病的治疗。

    0

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    2019-07-12 misszhang

    谢谢MedSci提供最新的资讯

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