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上海儿童特应性皮炎频发,“慢病”需长期管理

2017-05-26 许珈 澎湃新闻

特应性皮炎是一种慢性、复杂性、炎症性皮肤病。其发病原因比较复杂,与遗传、环境、免疫异常以及皮肤屏障功能等等有关。复旦大学附属华山医院皮肤科主任徐金华教授介绍,作为一种过敏性疾病,特应性皮炎和环境污染程度、城市化发展水平紧密相关。这也是上海地区特应性皮炎频发、发病率明显高于全国水平的主要原因。与普通湿疹不同,特应性皮炎是一种由免疫问题引发的“难治型湿疹”。如果不及时采取科学恰当的治疗,可能会难以摆脱

特应性皮炎是一种慢性、复杂性、炎症性皮肤病。其发病原因比较复杂,与遗传、环境、免疫异常以及皮肤屏障功能等等有关。复旦大学附属华山医院皮肤科主任徐金华教授介绍,作为一种过敏性疾病,特应性皮炎和环境污染程度、城市化发展水平紧密相关。这也是上海地区特应性皮炎频发、发病率明显高于全国水平的主要原因。

与普通湿疹不同,特应性皮炎是一种由免疫问题引发的“难治型湿疹”。如果不及时采取科学恰当的治疗,可能会难以摆脱,纠缠患者一生。一般情况下,特应性皮炎的患者会有瘙痒、干燥、红肿、过敏反应、皮肤苔藓样变五大主要皮肤表现。大部分患者都表现为越痒越抓、越抓越痒,进而加重皮肤炎症。

目前,临床上针对特应性皮炎常见的治疗药物是外用糖皮质激素。但是,长期使用激素可能引发激素依赖或其他多种副作用,并进一步损害皮肤屏障功能。

很多人不明白什么是皮肤屏障。复旦大学附属华山医院皮肤科教授李巍解释,如果将皮肤看作是一道墙,那么正常的皮肤是平整坚实的“墙”,而特应性皮炎患者的皮肤则是充满了“破洞”的“墙”。屏障功能受损,就好比皮肤这道“墙”上破了洞,外界的细菌、过敏原可以轻易通过,使病情反复发作。

作为一种慢性疾病,特应性皮炎和糖尿病高血压一样,需要长期规范的管理。李巍教授主张患者进行长期治疗,也就是说不能因为症状消失了就停止治疗,而应该遵循医嘱,在皮疹消退后逐步减少药物用量,再慢慢停药。或是在快要出现症状前就主动用药,达到长期不复发的治疗目的。

当然,用什么药也得听医生的。不要一谈到激素就“恐慌”。李巍教授表示,大部分特应性皮炎的患者在急性期还是首选外用激素,但一般也就用个3-5天,不会产生不良反应。80%以上的患者,都可以通过激素+保湿剂的方法,控制住病情。

在症状消退后,特应性皮炎的患者也要注重日常护理。李巍教授给出3点建议:

1.正确沐浴:皮肤上残留的痂皮容易滋生病毒,沐浴有助于清楚并减少表皮微生物的数量。推荐温水快速淋浴,每次5-10分钟,可以使用低敏无刺激的洁肤用品。干燥性皮肤宜减少沐浴次数,尽量不用清洁用品。沐浴结束后即刻外用保湿剂滋润皮肤。

2.外用润肤保湿剂:外用润肤剂是特应性皮炎的基础治疗,非常重要。在沐浴后用毛巾把水蘸干,然后立即使用润肤剂;不沐浴也要单纯使用润肤剂。丙二醇对2岁以下儿童皮肤有刺激现象,应避免使用。避免使用含有花生、燕麦等蛋白质变应原及半抗原的润肤剂。

3. 避免诱发和加重因素:尽量避免一切可能的刺激。应尽量穿棉制品衣服,以宽松为宜;避免用力搔抓和摩擦;避免过度清洁皮肤,尤其是烫洗和过度使用肥皂;避免环境温度过热,减少汗液的刺激;注意保持清洁的生活环境,减少如屋尘螨、动物毛、花粉、真菌等变应原;注意观察对所进食物的反应,避免食用致敏食物。

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content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-30 laoli

    特应性皮炎很顽固,家长着急,需要全面管理,提高依从性!

    0

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content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-30 meiliwuxian

    学习了

    0

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content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 美丽明天在等我

    特应性皮炎的患者也要注重日常护理,不要只寄希望于药物治疗

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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLB2lWFzjaQjxC33RfYGdWpDovtkkdhzWmm9c4lRfGccXhIurkRaLuS5VBHDGBbAOTm2bWazV6x9wg/0, createdBy=342e1692193, createdName=Arthur M, createdTime=Sat May 27 09:33:14 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203092, encodeId=a58a20309274, content=学习,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Sat May 27 06:53:41 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203077, encodeId=e38a2030e781, content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 186****0580(小山羊)

    学习了谢谢了。

    0

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content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 Arthur M

    学习了

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content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 执着追梦

    学习,感谢分享

    0

  10. 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CST 2017, time=2017-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204291, encodeId=3635204291af, content=特应性皮炎很顽固,家长着急,需要全面管理,提高依从性!, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Tue May 30 07:28:55 CST 2017, time=2017-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204209, encodeId=335d20420980, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Tue May 30 06:04:36 CST 2017, time=2017-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1274509, encodeId=d17612e4509ab, content=<a href='/topic/show?id=face28349b6' target=_blank style='color:#2F92EE;'>#儿童特应性皮炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28349, encryptionId=face28349b6, topicName=儿童特应性皮炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sun May 28 12:47:00 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203272, encodeId=9d982032e2c3, content=特应性皮炎的患者也要注重日常护理,不要只寄希望于药物治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLB2lWFzjaQjxC33RfYGdWpDovtkkdhzWmm9c4lRfGccXhIurkRaLuS5VBHDGBbAOTm2bWazV6x9wg/0, createdBy=342e1692193, createdName=Arthur M, createdTime=Sat May 27 09:33:14 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203092, encodeId=a58a20309274, content=学习,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Sat May 27 06:53:41 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203077, encodeId=e38a2030e781, content=针对应急性皮炎有了很深刻的了解,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/08/24/26b17bef207f5a16bb76644d2b22859e.jpg, createdBy=799d1992408, createdName=流逝的青春, createdTime=Sat May 27 06:47:21 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 流逝的青春

    针对应急性皮炎有了很深刻的了解,学习了!

    0

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