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J Clin Periodontol:管理牙龈炎症可有效降低全身炎症水平,提高生活质量

2022-08-26 MedSci原创 MedSci原创

牙菌斑诱发的牙龈炎被定义为主要由牙齿生物膜堆积引起的特定部位的炎症状况。大量研究表明,牙龈炎的存在会影响口腔健康相关的生活质量(OHRQoL),主要是儿童/青少年,但是缺乏关于治疗影响的信息。

牙菌斑诱发的牙龈炎被定义为主要由牙齿生物膜堆积引起的特定部位的炎症状况。大量研究表明,牙龈炎的存在会影响口腔健康相关的生活质量(OHRQoL),主要是儿童/青少年,但是缺乏关于治疗影响的信息。近日,发表于J Clin Periodontol的一项研究比较了受全身性牙龈炎影响的患者采用电动牙刷和强化口腔卫生指导(OHI)与常规习惯(无OHI)后1个月的炎症标志物水平、口腔健康相关的生活质量(OHRQoL)和牙龈参数。

研究共纳入140名患有广泛性牙龈炎的受试者,随机分配接受OHI或无OHI。在基线和1个月的随访中收集全口斑块/出血评分(FMPS/FMBS)、血清高敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)以及口腔健康影响档案-14问卷。

 

结果显示,在1个月的随访时,在OHI组中,受试者FMPS和FMBS明显减少(P<0.01),hs-CRP和IL-6的水平也显著降低(P<0.01),OHRQoL也明显改善(P<0.01)。在无OHI的情况下,只有口腔参数有小幅降低。OHI和无OHI之间牙龈炎的解决存在显著差异(分别为89%和7%,P<0.01)。逻辑多变量回归分析结果表明,CRP和IL-6阈值均低于既定的健康年轻人中,FMBS≤8%与OR为13有关(p = 0.04)。

综上所述,该研究结果表明,牙龈炎的解决决定了降低牙龈炎症和斑块水平的重要性,以及全身性炎症标志物和生活质量的改善。

 

原始出处:

 

Marina Perić, et al., Treatment of gingivitis is associated with reduction of systemic inflammation and improvement of oral health-related quality of life: A randomized clinical trial. J Clin Periodontol. 2022 Sep;49(9):899-910. doi: 10.1111/jcpe.13690.  

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