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SCI REP:阻塞性睡眠呼吸暂停与哮喘的关系分析!

2017-06-22 xing.T MedSci原创

这项研究表明哮喘患者阻塞性睡眠呼吸暂停的患病率相当高,甚至高于阻塞性睡眠呼吸暂停风险和SDB的患病率,对伴有阻塞性睡眠呼吸暂停/阻塞性睡眠呼吸暂停风险/SDB的哮喘患者应进行睡眠研究。

近日,Scientific reports 杂志上发表了一篇荟萃分析文章,该研究旨在评估阻塞性睡眠呼吸暂停(OSA)与哮喘之间存在的关系。

研究人员通过对几个电子数据库进行检索,确定了相关文献;并且采用随机效应荟萃分析得到了哮喘患者汇总估计的阻塞性睡眠呼吸暂停患病率、阻塞性睡眠呼吸暂停风险以及睡眠呼吸紊乱(SDB),同时,还获得了哮喘患者和非哮喘患者之间发病率合并的比值比。

在成年哮喘患者中,研究人员发现阻塞性睡眠呼吸暂停、阻塞性睡眠呼吸暂停的风险以及SDB的患病率(95%可信区间)分别为49.50[36.39-62.60] %、27.50[19.31-35.69] %和19.65[14.84-24.46]%。相比于没有哮喘的患者,哮喘患者患有阻塞性睡眠呼吸暂停、阻塞性睡眠呼吸暂停风险和SDB的几率分别要高出2.64[1.76-3.52]、3.73[2.90-4.57]和1.73[1.11-2.36]倍(所有P<0.00001)。与没有阻塞性睡眠呼吸暂停的哮喘患者相比,患有阻塞性睡眠呼吸暂停的成年哮喘患者体重指数显著升高。

这项研究表明哮喘患者阻塞性睡眠呼吸暂停的患病率相当高,甚至高于阻塞性睡眠呼吸暂停风险和SDB的患病率,对伴有阻塞性睡眠呼吸暂停/阻塞性睡眠呼吸暂停风险/SDB的哮喘患者应进行睡眠研究。

原始出处:

De-Lei Kong,et al. Association of Obstructive Sleep Apnea with Asthma: A Meta-Analysis.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-04446-6

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    2017-09-03 tomyang96
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    2017-06-26 杨利洪

    学习了分享了

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1696733, encodeId=cfe31696e33f9, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sun Sep 03 15:31:00 CST 2017, time=2017-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989045, encodeId=99e51989045b3, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sun Nov 19 17:31:00 CST 2017, time=2017-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215447, encodeId=af1021544ef8, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Mon Jun 26 06:50:40 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596493, encodeId=693a159649304, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Sat Jun 24 09:31:00 CST 2017, time=2017-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214436, encodeId=24f8214436da, content=谢谢!学习了,, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220317/1c3b2db4747d42e88e5018b394979434/be0fcebf07344e9ab886c37c502e2f29.jpg, createdBy=6bb22051299, createdName=微笑人参, createdTime=Fri Jun 23 18:25:44 CST 2017, time=2017-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214051, encodeId=694521405188, content=这项研究表明哮喘患者阻塞性睡眠呼吸暂停的患病率相当高,甚至高于阻塞性睡眠呼吸暂停风险和SDB的患病率,对伴有阻塞性睡眠呼吸暂停/阻塞性睡眠呼吸暂停风险/SDB的哮喘患者应进行睡眠研究。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Jun 22 20:15:08 CST 2017, time=2017-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214039, encodeId=ce4021403979, content=学习了很多的事情,, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2dD8SUAwqrufRiaKMGaaBScoAzEicJJibuu3wCIWWQxoLgS2UOBx1vsPe3faZtAiatc0pTWlS6868zZH/0, createdBy=0a231960988, createdName=胖红, createdTime=Thu Jun 22 19:25:54 CST 2017, time=2017-06-22, status=1, ipAttribution=)]
    2017-06-23 微笑人参

    谢谢!学习了,

    0

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    2017-06-22 有备才能无患

    这项研究表明哮喘患者阻塞性睡眠呼吸暂停的患病率相当高,甚至高于阻塞性睡眠呼吸暂停风险和SDB的患病率,对伴有阻塞性睡眠呼吸暂停/阻塞性睡眠呼吸暂停风险/SDB的哮喘患者应进行睡眠研究。

    0

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    2017-06-22 胖红

    学习了很多的事情,

    0

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Am J Resp Crit Care:2型糖尿病患者的阻塞性睡眠呼吸暂停与视网膜病变!

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