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Diabetes Care:糖尿病患者体质指数与死亡风险关系有种族差异

2012-03-17 MedSci 医学论坛网

  美国学者的一项研究表明,在非洲裔美国人和高加索人糖尿病患者中可观察到体质指数(BMI)与死亡风险呈矛盾相关。论文于2012年3月7日在线发表于《糖尿病护理》(Diabetes Care)杂志。   此项前瞻性观察研究共纳入2013例非洲裔美国人、2000例高加索人和143例种族未知的受试者。对BMI、心脏危险因素、用药和代谢当量(MET)最大运动能力进行评估。在各BMI和适应性分类

  美国学者的一项研究表明,在非洲裔美国人和高加索人糖尿病患者中可观察到体质指数(BMI)与死亡风险呈矛盾相关。论文于2012年3月7日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  此项前瞻性观察研究共纳入2013例非洲裔美国人、2000例高加索人和143例种族未知的受试者。对BMI、心脏危险因素、用药和代谢当量(MET)最大运动能力进行评估。在各BMI和适应性分类范畴中评估全因死亡率。

   结果显示,中位随访7.5年期间共出现1074例死亡。可观察到BMI-死亡率的矛盾相关;与肥胖分类者相比(BMI ≥35 kg/m2),在BMI处于18.5~24.9 kg/m2的受试者中风险显著升高。与高加索人相比,在非洲裔美国人中上述相关性减弱。在整个人群和BMI各分类中,适应性-死亡风险相关表现为逆向、独立并且分级。运动能力每增加1-MET,死亡风险降低12%。

  链接:

  BMI–Mortality Paradox and Fitness in African American and Caucasian Men With Type 2 Diabetes

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    2012-12-25 hb2008ye
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NEJM:146万成年白人中的体质指数与死亡率

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