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J Clin Periodontol:非手术牙周治疗前后血清RBP4水平的变化

2018-02-24 MedSci MedSci原创

我们旨在评估体型消瘦/肥胖慢性牙周炎(CP)患者牙周治疗前后的血清RBP4水平,以确定其与牙周炎的关系。

我们旨在评估体型消瘦/肥胖慢性牙周炎(CP)患者牙周治疗前后的血清RBP4水平,以确定其与牙周炎的关系。

实验共招募了112名体型消瘦和119名肥胖受试者。在非手术牙周治疗三个月前后评估CP患者牙周,人体测量学,生化参数和血清TNF-α,IL-6,hs-CRP和RBP4的水平。

结果发现,血清RBP4水平与牙周炎发生概率增加相关(OR = 1.60; 95%CI:1.02-2.50),显示CP患者在瘦和肥胖人群中的RBP4水平高于无CP者(3.35对3.06和3.74 vs 3.21)。在牙周治疗后,除了探诊深度(PD)≥4mm的牙齿数目, RBP4和TNF-α均下降,所有牙周参数均有相同程度的改善。在多变量回归模型中,PD≥4mm的牙齿数与RBP4独立相关(β= 0.192)。

结论:非手术牙周治疗前后RBP4水平与慢性牙周炎相关。

原始出处:

Mayte Martinez-Herrera, et al. Levels of serum retinol-binding protein 4 before and after non-surgical periodontal treatment in lean and obese subjects: An interventional study. Journal of Clincal Periodontology. 2018 March. doi:10.1111/jcpe.12840

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    2018-08-15 feather89
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    2018-04-20 jyzxjiangqin

    非手术牙周治疗.

    0

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    2018-04-07 jyzxjiangqin

    非手术牙周治疗前后血清.

    0

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    2018-03-09 jyzxjiangqin

    非手术牙周治疗.

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1727088, encodeId=93791e27088c3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 15 06:55:00 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793155, encodeId=1ea71e9315594, content=<a href='/topic/show?id=2a5c151e967' target=_blank style='color:#2F92EE;'>#RBP4水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15179, encryptionId=2a5c151e967, topicName=RBP4水平)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Tue Apr 03 11:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307519, encodeId=98f030e519cf, content=非手术牙周治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Apr 20 07:19:13 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303454, encodeId=323e3034544a, content=非手术牙周治疗前后血清., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Apr 07 07:07:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294426, encodeId=f9a12944260c, content=非手术牙周治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 09 07:02:48 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=291296, encodeId=03c3291296fe, content=非手术牙周治疗前后血清的变化., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue Feb 27 07:17:18 CST 2018, time=2018-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450774, encodeId=21bf1450e74bc, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Feb 26 13:55:00 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493513, encodeId=ea0514935133a, content=<a href='/topic/show?id=dc4c6e51457' target=_blank style='color:#2F92EE;'>#牙周治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67514, encryptionId=dc4c6e51457, topicName=牙周治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc259064725, createdName=cooco, createdTime=Mon Feb 26 13:55:00 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=290674, encodeId=b1612906e4de, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sun Feb 25 05:37:28 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-02-27 jyzxjiangqin

    非手术牙周治疗前后血清的变化.

    0

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  8. [GetPortalCommentsPageByObjectIdResponse(id=1727088, encodeId=93791e27088c3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 15 06:55:00 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793155, encodeId=1ea71e9315594, content=<a href='/topic/show?id=2a5c151e967' target=_blank style='color:#2F92EE;'>#RBP4水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15179, encryptionId=2a5c151e967, topicName=RBP4水平)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Tue Apr 03 11:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307519, encodeId=98f030e519cf, content=非手术牙周治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Apr 20 07:19:13 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303454, encodeId=323e3034544a, content=非手术牙周治疗前后血清., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Apr 07 07:07:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294426, encodeId=f9a12944260c, content=非手术牙周治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 09 07:02:48 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=291296, encodeId=03c3291296fe, content=非手术牙周治疗前后血清的变化., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue Feb 27 07:17:18 CST 2018, time=2018-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450774, encodeId=21bf1450e74bc, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Feb 26 13:55:00 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493513, encodeId=ea0514935133a, content=<a href='/topic/show?id=dc4c6e51457' target=_blank style='color:#2F92EE;'>#牙周治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67514, encryptionId=dc4c6e51457, topicName=牙周治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc259064725, createdName=cooco, createdTime=Mon Feb 26 13:55:00 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=290674, encodeId=b1612906e4de, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sun Feb 25 05:37:28 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1727088, encodeId=93791e27088c3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 15 06:55:00 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793155, encodeId=1ea71e9315594, content=<a href='/topic/show?id=2a5c151e967' target=_blank style='color:#2F92EE;'>#RBP4水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15179, encryptionId=2a5c151e967, topicName=RBP4水平)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Tue Apr 03 11:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307519, encodeId=98f030e519cf, content=非手术牙周治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Apr 20 07:19:13 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303454, encodeId=323e3034544a, content=非手术牙周治疗前后血清., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Apr 07 07:07:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294426, encodeId=f9a12944260c, content=非手术牙周治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 09 07:02:48 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=291296, encodeId=03c3291296fe, content=非手术牙周治疗前后血清的变化., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue Feb 27 07:17:18 CST 2018, time=2018-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450774, encodeId=21bf1450e74bc, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Feb 26 13:55:00 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493513, encodeId=ea0514935133a, content=<a href='/topic/show?id=dc4c6e51457' target=_blank style='color:#2F92EE;'>#牙周治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67514, encryptionId=dc4c6e51457, topicName=牙周治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc259064725, createdName=cooco, createdTime=Mon Feb 26 13:55:00 CST 2018, time=2018-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=290674, encodeId=b1612906e4de, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sun Feb 25 05:37:28 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-02-25 121832a9m88暂无昵称

    学习了

    0

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