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ACOG:在女性群体中的无症状性镜下血尿

2017-06-07 qinqiyun MedSci原创

无症状性镜下血尿在女性中很常见,而无症状性镜下血尿又是泌尿道肿瘤的重要临床特征,然而女性患膀胱癌和肾癌的风险远低于男性。ACOG和AUGS推荐对于无症状、低风险、无吸烟史的年龄介于35-50岁的女性,只有当尿检出现平均每高倍镜下多于25个红细胞时进行泌尿道肿瘤风险的评估。

无症状性镜下血尿在女性中很常见,而无症状性镜下血尿又是泌尿道肿瘤的重要临床特征,然而女性患膀胱癌和肾癌的风险远低于男性。因此,对于无症状性镜下血尿的诊断标准及是否进一步进行评估的指南,或许不能同时适用于男性和女性。近期,ACOG发表了一篇文章,推荐制备针对无症状性镜下血尿性别特异性的诊断指南。

无症状性镜下血尿是泌尿道肿瘤的重要临床特征。多年来无症状性镜下血尿的界定一直在变化。此外,最初的证据是基于来自男性患者的数据。然而,患者是男性或女性,会影响无症状性镜下血尿的鉴别诊断,而且,女性患泌尿道恶性肿瘤(膀胱、输尿管、肾)风险明显低于男性。大于60岁、有吸烟史的女性,出现肉眼血尿则是泌尿道癌症的强有力的指证。在小于50岁低风险且无吸烟史的女性中,无肉眼血尿并且平均每高倍镜下低于25个红细胞,患有泌尿道恶性肿瘤的风险不高于0.5%。此时,进行评估可能弊大于利不是很划算。有数据支持更改目前低风险人群的血尿诊断指标。ACOG和AUGS支持机构出台针对镜下血尿的新的诊断指南,对数据进行性别特异化分析和提出实用性的性别特异性的建议。同时,ACOG和AUGS推荐对于无症状、低风险、无吸烟史的年龄介于35-50岁的女性,只有当尿检出现平均每高倍镜下多于25个红细胞时进行泌尿道肿瘤风险的评估。

原始出处:

Nager CW,Sung VW,Whiteside JL.Asymptomatic microscopic hematuria in women. ACOG.June,2017. https://doi.org/10.1097/AOG.0000000000002059。

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    2018-01-12 xjy13
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    2017-06-08 quxin068
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    2017-06-08 仁心济世

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