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Prenat Diagn:胎儿轻度侧脑室增宽无须惶恐

2015-04-23 MedSci译 MedSci原创

随着产前筛查和诊断的推进,现在女性妊娠后都知道要去医院建卡,孕期行常规产检,而B超在产前检查中占有举足轻重的地位。但是当B超提示胎儿轻度侧脑室增宽(10-15 mm)时,很多孕妇和家属都会担心是不是宝宝的大脑有问题。Baffero GM等人对产前B超提示胎儿轻度侧脑室增宽(10-15 mm),而没有其他结构异常的正常核型胎儿,且母儿无感染的情况下,进行了一项研究,随访统计了产后脑异常的发生率,并且


随着产前筛查和诊断的推进,现在女性妊娠后都知道要去医院建卡,孕期行常规产检,而B超在产前检查中占有举足轻重的地位。但是当B超提示胎儿轻度侧脑室增宽(10-15 mm)时,很多孕妇和家属都会担心是不是宝宝的大脑有问题。

Baffero GM等人对产前B超提示胎儿轻度侧脑室增宽(10-15 mm),而没有其他结构异常的正常核型胎儿,且母儿无感染的情况下,进行了一项研究,随访统计了产后脑异常的发生率,并且探究反应脑异常的高危因素是什么。

该研究共纳入130名产前B超提示只伴有轻度侧脑室增宽(10-15 mm)的胎儿,随访发现其中有9名(6.9%)诊断为脑异常,在这之中,有6名(66.7%)是产前胎儿MRI确诊/怀疑脑部异常。研究者通过多变量分析发现,只有随访B超发现持久性或进行性侧脑室增宽才能唯一预测脑异常或是其高危因素(p = 0.001, OR 21.1 [95%CI: 3.6-122.7])。

研究结果表明,B超提示胎儿轻度侧脑室增宽后无须惶恐,需要密切随访B超,才能知道胎儿是否具有高度的脑异常的危险性。如果随访表现为持久性或进行性轻度侧脑室增宽,则需要对胎儿行MRI或新生儿影像学检查。

原始出处:

Baffero GM, Crovetto F, Fabietti I, Boito S, Fogliani R, Fumagalli M, Triulzi F, Mosca F, Fedele L, Persico N: Prenatal ultrasound predictors of postnatal major cerebral abnormalities in fetuses with apparently isolated mild ventriculomegaly. Prenatal diagnosis 2015.

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    2016-04-07 王明星

    受教了!谢谢!

    0

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    2015-06-08 liye789132251
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    2015-10-05 kcb069
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  5. [GetPortalCommentsPageByObjectIdResponse(id=76162, encodeId=79b4e6162f8, content=受教了!谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0c881700851, createdName=王明星, createdTime=Thu Apr 07 06:16:00 CST 2016, time=2016-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880610, encodeId=f68118806108b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Mon Jun 08 05:34:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085159, encodeId=cfb720851599d, content=<a href='/topic/show?id=53f72696507' target=_blank style='color:#2F92EE;'>#侧脑室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26965, encryptionId=53f72696507, topicName=侧脑室)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87b1109, createdName=kcb069, createdTime=Mon Oct 05 13:34:00 CST 2015, time=2015-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637082, encodeId=f368163e082bc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Dec 10 08:34:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23560, encodeId=cd8223560d8, content=我觉得有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22221, encodeId=2f922222150, content=很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=175.25.189.**, createdTime=Tue Apr 28 23:36:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1630513, encodeId=c2aa1630513c0, content=<a href='/topic/show?id=80f484805a4' target=_blank style='color:#2F92EE;'>#脑室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84805, encryptionId=80f484805a4, topicName=脑室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3eab21540873, createdName=tastas, createdTime=Sat Apr 25 09:34:00 CST 2015, time=2015-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21814, encodeId=9dbc2181436, content=学校学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Thu Apr 23 22:25:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21811, encodeId=b58421811ac, content=点赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Thu Apr 23 22:24:00 CST 2015, time=2015-04-23, status=1, ipAttribution=)]
    2015-05-15 JinFish

    我觉得有用

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=76162, encodeId=79b4e6162f8, content=受教了!谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0c881700851, createdName=王明星, createdTime=Thu Apr 07 06:16:00 CST 2016, time=2016-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880610, encodeId=f68118806108b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Mon Jun 08 05:34:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085159, encodeId=cfb720851599d, content=<a href='/topic/show?id=53f72696507' target=_blank style='color:#2F92EE;'>#侧脑室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26965, encryptionId=53f72696507, topicName=侧脑室)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87b1109, createdName=kcb069, createdTime=Mon Oct 05 13:34:00 CST 2015, time=2015-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637082, encodeId=f368163e082bc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Dec 10 08:34:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23560, encodeId=cd8223560d8, content=我觉得有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22221, encodeId=2f922222150, content=很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=175.25.189.**, createdTime=Tue Apr 28 23:36:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1630513, encodeId=c2aa1630513c0, content=<a href='/topic/show?id=80f484805a4' target=_blank style='color:#2F92EE;'>#脑室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84805, encryptionId=80f484805a4, topicName=脑室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3eab21540873, createdName=tastas, createdTime=Sat Apr 25 09:34:00 CST 2015, time=2015-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21814, encodeId=9dbc2181436, content=学校学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Thu Apr 23 22:25:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21811, encodeId=b58421811ac, content=点赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Thu Apr 23 22:24:00 CST 2015, time=2015-04-23, status=1, ipAttribution=)]
    2015-04-28 175.25.189.**

    很有用

    0

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    2015-04-25 tastas
  8. [GetPortalCommentsPageByObjectIdResponse(id=76162, encodeId=79b4e6162f8, content=受教了!谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0c881700851, createdName=王明星, createdTime=Thu Apr 07 06:16:00 CST 2016, time=2016-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880610, encodeId=f68118806108b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Mon Jun 08 05:34:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085159, encodeId=cfb720851599d, content=<a href='/topic/show?id=53f72696507' target=_blank style='color:#2F92EE;'>#侧脑室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26965, encryptionId=53f72696507, topicName=侧脑室)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87b1109, createdName=kcb069, createdTime=Mon Oct 05 13:34:00 CST 2015, time=2015-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637082, encodeId=f368163e082bc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Dec 10 08:34:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23560, encodeId=cd8223560d8, content=我觉得有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22221, encodeId=2f922222150, content=很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=175.25.189.**, createdTime=Tue Apr 28 23:36:00 CST 2015, time=2015-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1630513, encodeId=c2aa1630513c0, content=<a href='/topic/show?id=80f484805a4' target=_blank style='color:#2F92EE;'>#脑室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84805, encryptionId=80f484805a4, topicName=脑室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3eab21540873, createdName=tastas, createdTime=Sat Apr 25 09:34:00 CST 2015, time=2015-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21814, encodeId=9dbc2181436, content=学校学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Thu Apr 23 22:25:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21811, encodeId=b58421811ac, content=点赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=223.104.5.**, createdTime=Thu Apr 23 22:24:00 CST 2015, time=2015-04-23, status=1, ipAttribution=)]
    2015-04-23 xiaoai5777

    学校学习

    0

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    2015-04-23 223.104.5.**

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