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Dig Dis & Sci:结肠克罗恩病相比于回肠或回结肠疾病相比疾病表现更温和。

2018-06-18 MedSci MedSci原创

目前有关结肠克罗恩病(CD)疾病特征的文献很少,尤其是在亚洲,炎症性肠病的负担在上升。本研究旨在描述结肠CD的疾病特征,并将其与回肠/回肠结肠克罗恩病的特征进行比较。

背景
目前有关结肠克罗恩病(CD)疾病特征的文献很少,尤其是在亚洲,炎症性肠病的负担在上升。本研究旨在描述结肠CD的疾病特征,并将其与回肠/回肠结肠克罗恩病的特征进行比较。

方法
这项回顾性研究纳入了2004年8月至2016年1月期间随访的成人CD(根据标准标准诊断,随访时间> 6个月)。根据蒙特利尔分类对疾病部位进行分类。数据记录了人口统计学特征,吸烟状况,疾病表型,疾病过程,接受治疗,住院和手术。

结果
在406名CD患者中,123名患有结肠克罗恩病[平均年龄(发病时)30.4±13.2岁,男性占59.3%],265名患有回肠/回结肠克罗恩病[平均年龄(发病时)32.9±13.8岁,男性占61.5%]。疾病表现(B1表型; 61.8%比46.4%,p= 0.003),肛周疾病(23.6% vs. 4.5%,p<0.001)和肠外表现(42.3% vs. 30.2%,p= 0.019)结果显示所有严重表型中结肠比回肠/回结肠克罗恩病。结肠CD中至少需要一个类固醇疗程的要求较低(72.7% vs 84.2%,p= 0.098)。结肠CD的总体手术要求明显较低(17.1%vs. 26.1%,p= 0.032)。

结论
与回肠/回肠结肠CD相比,结肠CD有着较低的疾病攻击性与较低手术要求。

原始出处:

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    2018-06-20 Tamikia
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    2018-06-19 龙胆草

    学习谢谢分享

    0

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    2018-06-19 飛歌

    学习了很有用不错

    0

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    2018-06-19 大爰

    学习了谢谢分享!!

    0

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    2018-06-19 wzb521zf

    一起学习学习

    0

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    2018-06-19 1dd8c52fm63(暂无匿称)

    学习学习.继续关注

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    2018-06-19 yjs木玉

    学习学习再学习

    0

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