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Stroke:缺血性卒中及急性心肌梗死后一年危险因素控制情况的比较

2018-01-03 国际循环编辑部 国际循环

近日,Stroke发表的一项最新研究对急性缺血性卒中或急性心肌梗死(AMI)患者出院后1年的血压、血脂及血糖控制情况进行了评估与对比分析。

近日,Stroke发表的一项最新研究对急性缺血性卒中或急性心肌梗死(AMI)患者出院后1年的血压、血脂及血糖控制情况进行了评估与对比分析。

研究者印第安纳大学的Bravata DM等,对2011年75家医疗机构住院的40230例患者中2127例缺血性卒中和4169例AMI患者进行分析,比较两者发病后危险因素控制情况。结果发现,与AMI患者相比,缺血性卒中患者实现血压控制达标(<40/90 mm Hg)比例较低(64%vs.77%,P<0.0001)。广义线性混合模型分析显示,校正患者及医疗机构相关协变量后,与缺血性卒中患者相比,AMI患者的血压控制率仍较高(OR=1.39, 95% CI: 1.21~1.51);但高脂血症控制情况(LDL-C<100 mg/dl)无显著统计学差异(P=0.534)。对伴有糖尿病患者的亚组分析显示,与缺血性卒中患者相比,AMI患者的血糖控制情况(糖化血红蛋白<9%)更低(OR=0.72,95%CI: 0.54~0.96)。

鉴于血压控制是卒中预防的基石,上述研究结果提示,未来有必要积极采取措施改善卒中后的血压管理状况。

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    2018-01-03 wqkm

    ^_^^_^^_^

    0

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    2018-01-03 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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由此可见,在一般人群中砷代谢产物与缺血性脑卒中的发生呈正相关。总的来说,这些发现提示甲基化的砷在卒中发病机制中发挥着潜在的作用,对未来脑血管研究具有重要意义。

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由此可见,血浆中镉浓度与缺血性卒中的发生既独立相关,又可与颈动脉斑块协同作用对其产生影响。这支持了镉促进颈动脉斑块易损性的假设,从而增加了斑块破裂和缺血性卒中的风险。

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