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J Clin Periodontol:维持期治疗对于控制牙周病变的重要性

2020-07-26 MedSci原创 MedSci原创

本研究旨在评估在3个月的维护间隔内,经超声波洗牙(US)或空气抛光(AP)治疗的维持性牙周炎的龈下微生物的变化。

本研究旨在评估在3个月的维护间隔内,经超声波洗牙(US)或空气抛光(AP)治疗的维持性牙周炎的龈下微生物的变化。

 

我们对17名维持期受试者(探诊出血[BOP%]≤25%,探诊深度[PD]≤5mm)进行了为期12周的US和AP随机分口对照试验。他们在基线、第2周、第8周和第12周进行监测。对136个龈下斑块样本的16S rDNA的V3-V4区域进行测序和分析。

 

结果显示,通过US或AP治疗可有效降低维持性牙周炎的PD、微生物丰富度、多样性、牙周炎相关微生物群和病原代谢。治疗后细菌重新定植,治疗12周后恢复到治疗前水平。超声洗牙组在降低BOP(%)、致病菌和代谢方面比AP组稍有优势。在3个月的间隔期内,维持组患者龈下社区的病原微生物群和共生微生物群保持平衡。

 

综上所述,该研究结果表明,US或AP治疗通过降低微生物多样性、牙周炎相关微生物群比例和病原代谢,有效降低了龈下微生物群的致病性。在3个月的单次维持时间内,有助于保持龈下社区的平衡和牙周状况的稳定。

 

原始出处:

 

Hongye LuYibing Zhao, et al., Microbiome in maintained periodontitis and its shift over a single maintenance interval of 3 months. J Clin Periodontol. 2019 Nov;46(11):1094-1104. doi: 10.1111/jcpe.13177. 

 

 

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    2021-06-05 mgqwxj
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    2020-10-16 feather89
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