J Periodontol：透明质酸对种植体周围炎龈下微生物群的影响

2020-06-27 网络网络

本研究的目的是评估透明质酸（HA）凝胶应用45天后，对种植体周围炎微生物菌群的影响。

本研究的目的是评估透明质酸（HA）凝胶应用45天后，对种植体周围炎微生物菌群的影响。

在种植体周围炎患者中进行了一项随机对照试验。在基线和治疗45天后用拭子收集样本，并采用16S rRNA测序技术检测龈下微生物。

对54例患者的基线和45天后108个样本进行了分析。在基线时，样品中获得了三个微生物组成不同的层，代表了与种植体周围炎相关的三个主要微生物群落。在用HA治疗后，第1层的任何变量均未显示任何差异，而在第2层中， Streptococcus，Veillonella，Rothia和Granulicatella降低（P <0.05）。同样，用HA治疗后，第3层的Prevotella和Campylobacter减少（P <0.05）。对照组第3层的微生物多样性增加（P <0.05），而HA治疗组多样性降低了（P <0.05）。

因此，HA可以降低种植体周围炎相关的微生物（尤其是早期定植细菌）的相对丰度，表明在疾病发展的早期具有特定作用。 HA不能改变非口腔相关菌属的相对丰度。重度种植体周围炎使用HA可以降低微生物α多样性，表明其具有抑制种植体周围细菌定植的作用。

原文出处：

Ana Soriano‐Lerma，Short‐term effects of hyaluronic acid on the subgingival microbiome in peri‐implantitis: A randomized controlled clinical trial. Journal of periodontology, 2020 June. Doi: 10.1002/JPER.19-0184

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2020-07-18 huangdf

#种植#

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2020-10-15 feather89

#PE#

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2020-08-04 14880a50m44暂无昵称

学习了

134 0
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2020-11-20 wjcjjian

#微生物#

78 0
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2020-06-29 kalseyzl

#透明质酸#

84 0
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2020-06-29 ms6279672939590805

#种植体#

93 0
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2020-06-29 zhu_jun9837

#微生物群#

84 0
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2020-06-28 qingfengqishi5

学习了，学习了

130 0

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