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UROLOGY:根治性前列腺切除术后存在抑郁症状和性欲低下的风险

2018-02-23 MedSci MedSci原创

在本项研究中研究人员评估了接受开放性或机器人辅助根治性前列腺切除术的患者的抑郁症状和性欲减退的比率和预测因素。

在本项研究中研究人员评估了接受开放性或机器人辅助根治性前列腺切除术的患者的抑郁症状和性欲减退的比率和预测因素。

本项研究共有811例患者术前进行IIEF (国际勃起功能指标)和BDI (Beck抑郁量表)评估,并在术后6、12、24、36个月进行随访。通过描述性统计和逻辑回归模型评估抑郁症状和性欲减退的比率和预测因子。

研究人员分析了416例采用机器人辅助根治性前列腺切除术和395例接受开放性根治性前列腺切除术的患者的数据。总体而言,术后患者出现抑郁症状,6个月为26.3%,36个月为36.7%。在所有分析术后的时间点(p <0.01), 行开放手术的患者BDI评分均显着高于机器人辅助根治性前列腺切除术患者。采用机器人辅助根治性前列腺切除术治疗的患者在每一个时间点的勃起功能恢复率均高于开放性根治性前列腺切除术(p <0.005)。术后6个月的性欲减退率为40.9%,24个月为34.1%。在所有随访中(均p <0.02),在接受开放性根治性前列腺切除术患者中,iiefsd - sd(性域)评分显着降低。年龄、开放根治性前列腺切除术和术后勃起功能障碍是BDI评分和性欲减退的独立预测因子。

结论
手术后的几个月,三名接受手术治疗的前列腺癌患者中,有一名仍有抑郁症状。接受机器人辅助根治性前列腺切除术的患者比接受开放性根治性前列腺切除术的患者有较轻的抑郁症状。在接受开放性根治性前列腺切除术的患者中,根治性前列腺切除术后性欲受到严重影响。

原始出处:
Luca Boeri.et al.Radical Prostatectomy: Early and Long-Term Outcomes in a Real-Life Setting.UROLOGY.2018.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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    2018-02-25 陆成振
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    2018-02-25 jeanqiuqiu
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    2018-02-24 忠诚向上

    好好学习一下

    0

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