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J Clin Periodontol:牙周治疗附加系统性抗菌治疗对代谢综合征指标的影响

2017-06-21 lishiting MedSci原创

这篇研究的目的是为了评估牙周基础治疗(BPT)附加抗菌治疗(AM)对代谢综合征(MetS)指标(腰围、收缩/舒张血压、高密度脂蛋白、甘油三酯和葡萄糖)的影响。

这篇研究的目的是为了评估牙周基础治疗(BPT)附加抗菌治疗(AM)对代谢综合征(MetS)指标(腰围、收缩/舒张血压、高密度脂蛋白、甘油三酯和葡萄糖)的影响。

110名牙周炎患者参与此项调查。参与者在不知道也不在意自己可能罹患MetS的情况下,研究对患者随机施加BPT(n=56)或BPT+AM(n=54),并在治疗后跟踪随访12个月。同时,未罹患MetS的患者人数也进行了统计确定。

结果显示,所有患者牙周情况均有所好转。然而,BPT+AM组的牙周袋深度要浅于BPT组。治疗后,收缩压(p <0.05)和甘油三酯(p <0.05)在随访期间明显降低。但是,在BPT+AM和BPT两组之间并未发现显著性差异。尽管没有患者认为自己两病并存,但是在治疗前仍有27.2%(n=30)的牙周炎患者经检查证实罹患MetS。治疗后,在第3个月随访时,这部分人群降至14.5%(p = 0.007),而在第6个月时升至17.3%(p = 0.017),第12个月时变为21.8%(p = 0.383)。

结论:尽管收缩压和甘油三酯有所降低,并且整个代谢指标都有一个短暂的改善,但是抗菌治疗结合BPT对MetS的指标并未产生任何额外效果。

原始出处

Bizzarro S, van der Velden U, et al. Effect of periodontal therapy with systemic antimicrobials on parameters of metabolic syndrome. J Clin Periodontol. 2017 Jun 16. doi: 10.1111/jcpe.12763.

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    2017-10-28 feather89
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    2017-06-27 lou.minghong

    存在正相关

    0

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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfBfgWn9nXBgH1sNSiaOAKhsKpN40jDHQKqcRzovau5VibLvREN8uxnu9sKoScBicHSiaDMmbveibFdrBiaD4k4IOPwlG/0, createdBy=b5d11730951, createdName=Jackie Li, createdTime=Fri Jun 23 08:09:08 CST 2017, time=2017-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214257, encodeId=757021425e1f, content=学习,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuEJWOf8El7MfqtlSpy4eWtPl5cxmNJ4ezwbFf5vtCeh53ITyabFpFIJfKTPlzdh6ibOibVONwHUbm9/0, createdBy=a4351715107, createdName=人间可客, createdTime=Fri Jun 23 08:01:37 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 Jackie Li

    学习

    0

  10. 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    2017-06-23 人间可客

    学习,谢谢分享

    0

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