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Chest:长期暴露于环境PM2.5和臭氧对老年人ARDS风险的影响

2019-04-03 xing.T 网络

由此可见,长期暴露于PM2.5和臭氧与美国老年人ARDS风险增加有关,包括低于目前年度国家环境空气质量标准的暴露。

长期暴露于直径小于2.5um的颗粒物(PM2.5)和臭氧污染会影响呼吸功能。急性呼吸窘迫综合征(ARDS)是一种致命的呼吸衰竭,在老年人中最常见。然而,很少有流行病学研究调查空气污染与ARDS风险之间的关系。

近日,呼吸领域权威杂志chest上发表了一篇研究文章,研究人员对2000-2012年期间≥65岁的美国医疗保险受益人进行了邮政编码级别估计的空气污染暴露和ARDS住院之间相关性的观察性研究。研究人员应用了一个双污染物的广义线性混合模型,调整性别、年龄、种族、家庭收入中位数、吸烟和天气。

该队列共有1164784名ARDS的住院患者。年平均PM2.5增加1ug/m3和臭氧浓度每增加1ppb与ARDS年入院率增加0.72%(95%CI为0.62-0.82)和0.15%(95%CI为0.08-0.22)相关。在低污染地区(年平均PM2.5水平<12ug/m3和年平均臭氧水平<45ppb),PM2.5和臭氧年增长率相同,ARDS年入院率分别增加1.50% (95%CI为1.27-1.72)和0.27%(95%CI为0.16-0.38)。

由此可见,长期暴露于PM2.5和臭氧与美国老年人ARDS风险增加有关,包括低于目前年度国家环境空气质量标准的暴露。

原始出处:

Jongeun Rhee,et al.Impact of Long-Term Exposures to Ambient PM2.5 and Ozone on Acute Respiratory Distress Syndrome (ARDS) Risk for Older Adults in the United States.chest.2019.https://doi.org/10.1016/j.chest.2019.03.017

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    2019-04-12 Smile2680
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    2019-10-22 drwjr
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    2019-04-05 xuqianhua

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