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JAMA Netw Open:中国学者:二手烟暴露会增加儿童ADHD风险

2021-06-14 MedSci原创 MedSci原创

烟还是戒了吧!

注意缺陷/多动障碍 (ADHD) 是一种常见的神经发育障碍,通常在儿童时期被诊断出来,全球学龄儿童的患病率为 5%  7%ADHD起病于童年期,影响可延续至成年,其主要特征是与发育水平不相称的注意缺陷和(或)多动冲动。ADHD不仅损害学习功能,还存在其他多方面、涉及生命全周期的生理和心理健康损害。

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近日,发表在JAMA Network Open杂志的一项研究显示,从怀孕到儿童期的二手烟暴露与学龄儿童出现 ADHD 症状密切相关,尤其是在产前和产后早期。

在这项横断面研究中,研究人员对来自20124月至20131月期间中国辽宁省48612618岁的儿童展开调查分析。通过学校老师向家长或监护人发放的调查问卷,收集每个儿童的二手烟暴露情况和ADHD症状数据。于2020914日至122日对数据进行了分析。ADHD 临床症状和亚型是基于从《精神疾病诊断和统计手册》(第四版)开发的有效工具进行测评,以估计二手烟暴露与 ADHD 症状和亚型的关联。

研究结果显示,共有45562名参与者完成了问卷并被纳入本研究,女孩占50.3%,平均年龄为11.0岁,4.8%ADHD症状。与未接触过二手烟的儿童相比,从怀孕到儿童时期曾经接触过(几率比[OR]1.5095%CI1.36-1.66)或总是接触二手烟(OR2.8895%CI2.55-3.25)的儿童患有ADHD症状和亚型的几率更高(ORs1.46[95%CI1.31-1.62]2.94[95%CI2.09-4.13])。在产前以及产后早期接触二手烟的儿童出现ADHD症状的概率更高。

二手烟暴露时间与学龄儿童(6-18 岁)患ADHD症状和亚型的关联

另外,研究人员发现,与未接触过二手烟的儿童相比,父亲每天抽10支或更多烟的儿童患ADHD症状和亚型的几率更高ORs1.48[95% CI1.28-1.70]2.25[95% CI1.29-3.93])。

当前父亲吸烟与ADHD 症状和亚型的关联

综上,在这项大型横断面研究中,研究人员发现从怀孕到童年的二手烟暴露与学龄儿童的 ADHD 症状和亚型相关。在考虑二手烟暴露的时间时,这种关联在产前和产后早期更为明显。此外,父亲吸烟的孩子出现ADHD 症状和亚型的几率更高。

原始出处

Li-Zi Lin, PhD1; Shu-Li Xu, MM1Qi-Zhen Wu, MM1; et al.Association of Prenatal, Early Postnatal, or Current Exposure to Secondhand Smoke With Attention-Deficit/Hyperactivity Disorder Symptoms in Children.JAMA Netw Open. 2021;4(5):e2110931. doi:10.1001/jamanetworkopen.2021.10931

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    2021-09-28 canlab
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    2021-06-19 feather89
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    2021-06-16 lg.zhao
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    2021-06-15 1356548325

    为了孩子也得戒烟啊

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1734374, encodeId=fffb1e34374fd, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Tue Sep 28 21:16:46 CST 2021, time=2021-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728974, encodeId=13481e28974de, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Jun 19 05:16:46 CST 2021, time=2021-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307611, encodeId=8528130e611ed, content=<a href='/topic/show?id=459f19e855' target=_blank style='color:#2F92EE;'>#ADHD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1978, encryptionId=459f19e855, topicName=ADHD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c737344, createdName=lg.zhao, createdTime=Wed Jun 16 06:16:46 CST 2021, time=2021-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1340139, encodeId=b4ee13401390f, content=<a href='/topic/show?id=77b0239266a' target=_blank style='color:#2F92EE;'>#二手烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23926, encryptionId=77b0239266a, topicName=二手烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1dfd2500156, createdName=12498c24m69暂无昵称, createdTime=Wed Jun 16 06:16:46 CST 2021, time=2021-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=973654, encodeId=66349e3654bd, content=为了孩子也得戒烟啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=67634708538, createdName=1356548325, createdTime=Tue Jun 15 09:35:02 CST 2021, time=2021-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036676, encodeId=c7e810366e61c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Jun 14 18:16:46 CST 2021, time=2021-06-14, status=1, ipAttribution=)]
    2021-06-14 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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