Baidu
map

Ann Intern Med:低摄入量与高摄入量的红肉对心脏代谢和癌症结局的影响

2019-10-04 xing.T MedSci原创

由此可见,确定性低至非常低的证据表明,限制红肉饮食可能对主要的心脏代谢结局以及癌症死亡率和发病率几乎没有影响。

很少有随机试验评估减少红肉摄入量对临床重要结局的影响。近日,内科学权威杂志Annals of Internal Medicine上发表了一篇研究文章,该研究旨在总结较少或较多红肉摄入量对成年人心脏代谢和癌症结局发生率的影响。

研究人员检索了EMBASE、CENTRAL、CINAHL、Web of Science和ProQuest,这些数据库的检索时间从成立开始至2018年7月,研究人员也检索了MEDLINE,检索时间自数据库成立至2019年4月,没有语言限制。研究人员选择了比较高红肉饮食与低红肉饮食的随机试验(以任何语言发表),组间的差异通过每周至少1顿进行分级,持续6个月或更长时间。由2名审稿人组成的团队独立提取数据并评估偏倚风险和证据的确定性。

12项符合条件的试验中,一项招募了48835名妇女的试验提供了最可信的证据,尽管其不确定性仍然很低,其表明少吃红肉的饮食对全因死亡率(风险比[HR]为0.99[95%CI为0.95-1.03])、心血管疾病死亡率(HR为0.98[95%CI为0.91-1.06])和心血管疾病(HR为0.99[95%CI为0.94-1.05])几乎没有影响或没有影响。该试验还提供了低至极低确定性的证据,即减少红肉饮食对癌症总体死亡率(HR为0.95[95%CI为0.89-1.01])和癌症的发生率影响很小或没有影响,包括直肠癌(HR为1.04 [95%CI为0.90-1.20])和乳腺癌(HR为0.97 [95%CI为0.90-1.04])。

由此可见,确定性低至非常低的证据表明,限制红肉饮食可能对主要的心脏代谢结局以及癌症死亡率和发病率几乎没有影响。 

原始出处:

Dena Zeraatkar,et al.Effect of Lower Versus Higher Red Meat Intake on Cardiometabolic and Cancer Outcomes: A Systematic Review of Randomized Trials FREE.AIM.2019.https://annals.org/aim/fullarticle/2752326/effect-lower-versus-higher-red-meat-intake-cardiometabolic-cancer-outcomes

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1860654, encodeId=125c1860654ad, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Mar 14 22:31:00 CST 2020, time=2020-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337208, encodeId=fe51133e208ac, content=<a href='/topic/show?id=f4c251404aa' target=_blank style='color:#2F92EE;'>#心脏代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51404, encryptionId=f4c251404aa, topicName=心脏代谢)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473611, encodeId=65c214e36112b, content=<a href='/topic/show?id=82d5e146799' target=_blank style='color:#2F92EE;'>#癌症结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71467, encryptionId=82d5e146799, topicName=癌症结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da3c7235007, createdName=xqptu, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610019, encodeId=3506161001972, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=)]
    2020-03-14 lmm397
  2. [GetPortalCommentsPageByObjectIdResponse(id=1860654, encodeId=125c1860654ad, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Mar 14 22:31:00 CST 2020, time=2020-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337208, encodeId=fe51133e208ac, content=<a href='/topic/show?id=f4c251404aa' target=_blank style='color:#2F92EE;'>#心脏代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51404, encryptionId=f4c251404aa, topicName=心脏代谢)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473611, encodeId=65c214e36112b, content=<a href='/topic/show?id=82d5e146799' target=_blank style='color:#2F92EE;'>#癌症结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71467, encryptionId=82d5e146799, topicName=癌症结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da3c7235007, createdName=xqptu, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610019, encodeId=3506161001972, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1860654, encodeId=125c1860654ad, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Mar 14 22:31:00 CST 2020, time=2020-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337208, encodeId=fe51133e208ac, content=<a href='/topic/show?id=f4c251404aa' target=_blank style='color:#2F92EE;'>#心脏代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51404, encryptionId=f4c251404aa, topicName=心脏代谢)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473611, encodeId=65c214e36112b, content=<a href='/topic/show?id=82d5e146799' target=_blank style='color:#2F92EE;'>#癌症结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71467, encryptionId=82d5e146799, topicName=癌症结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da3c7235007, createdName=xqptu, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610019, encodeId=3506161001972, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1860654, encodeId=125c1860654ad, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Mar 14 22:31:00 CST 2020, time=2020-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1337208, encodeId=fe51133e208ac, content=<a href='/topic/show?id=f4c251404aa' target=_blank style='color:#2F92EE;'>#心脏代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51404, encryptionId=f4c251404aa, topicName=心脏代谢)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIUEDhSibBFt8TicgFCCSBtW10SxVJicDpibTCucns8L1YaiaKpibWOkv8hYpJ0LeTVUH1Ab4sfica9bxiccA/132, createdBy=dd282500126, createdName=ms3830150583600765, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473611, encodeId=65c214e36112b, content=<a href='/topic/show?id=82d5e146799' target=_blank style='color:#2F92EE;'>#癌症结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71467, encryptionId=82d5e146799, topicName=癌症结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da3c7235007, createdName=xqptu, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610019, encodeId=3506161001972, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Oct 06 02:31:00 CST 2019, time=2019-10-06, status=1, ipAttribution=)]

相关资讯

Eur Heart J:吃红肉导致心脏病风险的机制

在同时进行的几项研究中,美国克利夫兰诊所的研究人员发现了新机制可以阐明经常吃红肉导致心脏病风险上升的原因和方式,以及肠道细菌在这一过程中所起的作用。

Gastroenterology:克罗恩病缓解期患者食用红肉不会增加复发风险

研究认为,对于处于克罗恩病缓解期的患者,食用红肉及加工肉类不会增加其疾病复发风险

Circulation:哈佛研究称,用植物蛋白替代红肉,更有利于控制心血管危险因素

哈佛大学公共卫生学院和普渡大学联合发布的一项新研究表明,用健康的植物蛋白替代红肉的饮食更有利于控制心血管疾病的危险因素,不建议用鱼或低质碳水化合物替代红肉。这项研究是第一个对采用其他特定类型的食物替代红肉对健康的影响的随机对照试验的荟萃分析,这项研究发表在《循环》杂志上。

Am J Clin Nutr:研究发现 红肉和白肉均可提高胆固醇水平

多年来,对于糖尿病、心脏病和某些癌症相关疾病,许多健康专家都认为将红肉换成白肉是最佳选择,因为白肉一直被认为是较好的选择。

Am J Obstet Gynecol:女人不能做肉食动物 否则子宫内膜异位症风险来报复

子宫内膜异位症是一种良性的雌激素依赖性妇科疾病,育龄女性的患病率约为10%。其病因尚未完全知晓。饮食或可通过影响甾体激素,从而影响子宫内膜异位症的发生风险。例如,红肉可降低性激素结合球蛋白(SHBG)并增加雌二醇浓度。

Circulation:肉、鱼、奶、蛋的摄入与缺血性心脏病的相关性

肉食与缺血性心脏病(IHD)发病机制的相关性尚不明确。研究人员在欧洲EPIC队列中研究肉类、鱼类、乳制品、蛋类食物与IHD风险之间的相关性。本项前瞻性研究共纳入欧洲9个国家的409885名男性和女性,对其饮食进行评估。在亚样本中测量血脂和血压。平均随访12.6年,7198名参与者发生心肌梗死或死于IHD。每增加100克红肉和加工肉的摄入量,IHD的危险比(HR)为1.19 (95% CI, 1.0

Baidu
map
Baidu
map
Baidu
map