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Arthritis Care Res :银屑病性关节炎疾病教育与认识的不足

2014-08-05 Elizabeth(编译) 睿医资讯

一项共识声明指出,银屑病性关节炎(PsA)仍有较高比例的患者诊断不足或漏诊。如患者和医师对该疾病加深认识、存在有效的筛查工具、有更加简明的方式确定何时适合转诊至风湿病医师处接受治疗,则可使患者更早接受治疗进而减轻疾病负担。根据美国国立卫生研究院的数据报告,每20个人中就有1名罹患银屑病,并发生PsA。病情较轻的患者仅数个关节受影响,病情严重者可致关节和脊柱僵硬、烧灼感、疼痛。PsA可能增高其他疾病

一项共识声明指出,银屑病性关节炎(PsA)仍有较高比例的患者诊断不足或漏诊。如患者和医师对该疾病加深认识、存在有效的筛查工具、有更加简明的方式确定何时适合转诊至风湿病医师处接受治疗,则可使患者更早接受治疗进而减轻疾病负担。

根据美国国立卫生研究院的数据报告,每20个人中就有1名罹患银屑病,并发生PsA。病情较轻的患者仅数个关节受影响,病情严重者可致关节和脊柱僵硬、烧灼感、疼痛。PsA可能增高其他疾病的风险,如心血管疾病、高血压、2型糖尿病或肥胖。

然而,7月21日在线发表于 Arthritis Care & Research 的共识声明指出,约50%的银屑病患者PsA情况诊断不足,且很多患者即使在确诊之后治疗仍是个问题。

2012年10月,伦敦银屑病性关节炎论坛组织了国际专家组以明确治疗和诊断方面的空白,并提出对这些未满足需求的解决方案。此专家组中来自英国利兹大学利兹分子医学研究所的Philip Helliwell及其同事发表了这篇声明。

经验丰富的风湿病医师能辨认出银屑病性关节炎,但发现可准确预示银屑病患者将进展为关节炎的生物标志物意义重大。除缺乏经验证的PsA鉴别工具外,临床医师和患者也并不了解如何将该疾病与炎症性关节炎或骨关节炎进行区分。

作者们在声明中写道,“我们应对最可能直接接触到PsA患者的医疗工作者进行PsA筛查教育,包括皮肤科医师、全科医师、眼科医师、骨科医师、风湿病医师、足病医师和理疗师。而其中最应对皮肤科医师进行重点教育,因为PsA患者的皮肤病情况可能更为严重。”

美国银屑病国家基金会的首席科学与医学官员Andrew D. Robertson对这篇共识声明表示了赞同,他认为理由充分的文档有助于领域聚焦,并按照重要性对改善患者护理的策略进行排序。“我不能肯定明天情况就会改变,但我能肯定这项共识声明为我们提供了指引,而且坦白地说,它推动我们继续我们正在进行的工作并拓展了我们的研究范围。我们无需开展新的研究,我们只需帮助普及疾病知识和教育以改变现况。”

共识声明的作者表示,他们仍不明确早期强化治疗能否预防疾病进展,避免生活质量受损、致残率增高、或治疗花费增高。但患病2年内就诊的患者疾病进展速度比患病2年后才就诊的患者要慢。

作者们在文章中总结表示,声明中提到的举措主要关注的是近期目标——如加强人们对PsA及其相关疾病负担的认识,以及长期目标——如制定并实施诊断与护理的一致标准,最终共识中所推荐的举措旨在改善PsA患者疾病相关的/功能性预后以及健康相关的生活质量。

原始出处:


Helliwell P1, Coates L, Chandran V, Gladman D, de Wit M, FitzGerald O, Kavanaugh A, Strand V, Mease PJ, Boehncke WH, Langley RG, Lubrano E, Maccarone M, Schulze-Koops H, Miceli-Richard C, Queiro R.Qualifying Unmet Needs and Improving Standards of Care in Psoriatic Arthritis.Arthritis Care Res (Hoboken). 2014 Jul 21. doi: 10.1002/acr.22404. [Epub ahead of print]

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    2014-08-07 lmm397
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    2014-08-07 zhaojie88

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