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ER:住宅绿化与婴幼儿过敏性疾病相关,妊娠期似乎是关键暴露窗口

2022-08-26 小文子 MedSci原创

研究发现了住宅绿化与婴幼儿过敏性疾病,尤其是湿疹的有害关联,妊娠期似乎是关键的暴露窗口。

生活环境中的绿化面积与过敏性疾病的发生有关。然而,幼儿早发性过敏的证据有限,关键暴露窗仍不清楚。Environmental Research杂志发表的一项研究调查了住宅绿化与婴幼儿期过敏性疾病之间的关联。

该前瞻性出生队列研究纳入了中国广州的522对母子。研究根据远程卫星数据,使用归一化差值植被指数(NDVI)、增强植被指数(EVI)和树木覆盖,量化了出生前、出生后和婴幼儿期(即出生后前1000天)的住宅绿化程度。根据2岁时的病历确定了医生诊断的过敏性疾病(湿疹、特应性皮炎、荨麻疹、过敏性鼻炎、过敏性结膜炎、食物过敏和哮喘)。进行广义线性回归验证绿化与过敏结局的相关性。

结果显示,婴幼儿期住宅 500m 缓冲区NDVI 和 EVI 值范围分别为0.06~0.70和0.03~0.46。在 500m 缓冲区的NDVI每增加0.1个单位与过敏性疾病(产前:OR=1.25;95%CI,1.02~1.53;出生后:OR=1.24;95%CI,1.02~1.52;婴幼儿期:OR=1.25,95%CI:1.02~1.53)和湿疹(产前:OR=1.28;95%CI,1.04~1.59;出生后:OR=1.24;95%CI,1.01~1.54;婴幼儿期:OR=1.26,95%CI:1.02~1.56)更高的发生几率有关。当使用 EVI 作为绿化指标时,结果是一致的。

研究观察到,妊娠期间的相关性比其他时期更明显(过敏性疾病:OR=1.63;95%CI,1.03~2.58;湿疹:OR=1.70;95%CI:1.04~2.78)。

这项研究发现了住宅绿化与婴幼儿过敏性疾病,尤其是湿疹的有害关联,妊娠期似乎是关键的暴露窗口。研究结果强调了城市规划发展友好绿色社区对改善孕产妇和儿童健康的重要性。

原文出处:

Lizi Lin, Yujing Chen,et al, The associations between residential greenness and allergic diseases in Chinese toddlers: A birth cohort study, Environmental Research,  2022, https://doi.org/10.1016/j.envres.2022.114003.

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  3. [GetPortalCommentsPageByObjectIdResponse(id=2047481, encodeId=617d204e48196, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Thu Aug 10 16:08:37 CST 2023, time=2023-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251340, encodeId=42551251340e6, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sat Aug 27 11:08:37 CST 2022, time=2022-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1241070, encodeId=7d5a12410e026, content=认真学习~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfb41991958, createdName=xulv123, createdTime=Fri Aug 26 07:07:48 CST 2022, time=2022-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1241058, encodeId=da1712410587a, content=住宅<a href='/topic/show?id=692de9170b5' target=_blank style='color:#2F92EE;'>#绿化#</a>与婴幼儿期<a href='/topic/show?id=b2f994044aa' target=_blank style='color:#2F92EE;'>#过敏性疾病#</a>,这是有害的结论,但是,要看看到是绿化的本身,还是绿化带来的<a href='/topic/show?id=f94a885926b' target=_blank style='color:#2F92EE;'>#蚊虫叮咬#</a>,以及<a href='/topic/show?id=d6248694182' target=_blank style='color:#2F92EE;'>#花粉过敏#</a>,以及部分树木可能会过敏(如<a href='/topic/show?id=c4481045958b' target=_blank style='color:#2F92EE;'>#杜鹃#</a>花,<a href='/topic/show?id=0b4d1045962c' target=_blank style='color:#2F92EE;'>#法国梧桐#</a>)等情况,才可能说明真相。目前这项研究还是太粗略,甚至形成误导性结论。这是不是说明,住在沙漠或无植被条件下,反而过敏更少了?这与我们认知并不相符,例如农村的绿化是优于城市的,但是过敏却更少。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79170, encryptionId=692de9170b5, topicName=绿化), TopicDto(id=94044, encryptionId=b2f994044aa, topicName=过敏性疾病), TopicDto(id=88592, encryptionId=f94a885926b, topicName=蚊虫叮咬), TopicDto(id=86941, encryptionId=d6248694182, topicName=花粉过敏), TopicDto(id=104595, encryptionId=c4481045958b, topicName=杜鹃), TopicDto(id=104596, encryptionId=0b4d1045962c, topicName=法国梧桐)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Fri Aug 26 00:52:05 CST 2022, time=2022-08-26, status=1, ipAttribution=)]
    2022-08-26 xulv123

    认真学习~~

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2047481, encodeId=617d204e48196, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Thu Aug 10 16:08:37 CST 2023, time=2023-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251340, encodeId=42551251340e6, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sat Aug 27 11:08:37 CST 2022, time=2022-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1241070, encodeId=7d5a12410e026, content=认真学习~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfb41991958, createdName=xulv123, createdTime=Fri Aug 26 07:07:48 CST 2022, time=2022-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1241058, encodeId=da1712410587a, content=住宅<a href='/topic/show?id=692de9170b5' target=_blank style='color:#2F92EE;'>#绿化#</a>与婴幼儿期<a href='/topic/show?id=b2f994044aa' target=_blank style='color:#2F92EE;'>#过敏性疾病#</a>,这是有害的结论,但是,要看看到是绿化的本身,还是绿化带来的<a href='/topic/show?id=f94a885926b' target=_blank style='color:#2F92EE;'>#蚊虫叮咬#</a>,以及<a href='/topic/show?id=d6248694182' target=_blank style='color:#2F92EE;'>#花粉过敏#</a>,以及部分树木可能会过敏(如<a href='/topic/show?id=c4481045958b' target=_blank style='color:#2F92EE;'>#杜鹃#</a>花,<a href='/topic/show?id=0b4d1045962c' target=_blank style='color:#2F92EE;'>#法国梧桐#</a>)等情况,才可能说明真相。目前这项研究还是太粗略,甚至形成误导性结论。这是不是说明,住在沙漠或无植被条件下,反而过敏更少了?这与我们认知并不相符,例如农村的绿化是优于城市的,但是过敏却更少。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79170, encryptionId=692de9170b5, topicName=绿化), TopicDto(id=94044, encryptionId=b2f994044aa, topicName=过敏性疾病), TopicDto(id=88592, encryptionId=f94a885926b, topicName=蚊虫叮咬), TopicDto(id=86941, encryptionId=d6248694182, topicName=花粉过敏), TopicDto(id=104595, encryptionId=c4481045958b, topicName=杜鹃), TopicDto(id=104596, encryptionId=0b4d1045962c, topicName=法国梧桐)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Fri Aug 26 00:52:05 CST 2022, time=2022-08-26, status=1, ipAttribution=)]
    2022-08-26 小小医者

    住宅#绿化#与婴幼儿期#过敏性疾病#,这是有害的结论,但是,要看看到是绿化的本身,还是绿化带来的#蚊虫叮咬#,以及#花粉过敏#,以及部分树木可能会过敏(如#杜鹃#花,#法国梧桐#)等情况,才可能说明真相。目前这项研究还是太粗略,甚至形成误导性结论。这是不是说明,住在沙漠或无植被条件下,反而过敏更少了?这与我们认知并不相符,例如农村的绿化是优于城市的,但是过敏却更少。

    0

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