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Dig Dis Sci:肠易激综合征中的腹胀严重程度与心理因素和合并症相关

2019-06-10 不详 MedSci原创

腹胀是肠易激综合征(IBS)中最令人烦恼的症状之一,但其与其他症状的关联尚未得到很好的描述。因此,本项研究旨在探究肠易激综合征造成的腹胀与心理困扰和共病症状之间的关联。

背景
腹胀是肠易激综合征(IBS)中最令人烦恼的症状之一,但其与其他症状的关联尚未得到很好的描述。因此,本项研究旨在探究肠易激综合征造成的腹胀与心理困扰和共病症状之间的关联。

方法
研究人员对其医疗中心的IBS患者进行了横断面研究,将这些患者与有或没有腹胀的健康对照进行比较。最后通过评估受试者的IBS及其亚型,疼痛严重程度,症状严重程度,心理障碍,合并症以及饮食模式来进行分析。

结果
本项研究共调查了484名受试者。与IBS-B相比,IBS + B受试者便秘率较高(30%vs 15 %,p = 0.191),腹泻率较低(70%vs 85 %,p = 0.191)。腹胀严重程度与IBS症状严重程度(r = 0.397,p = 0.000),疼痛严重程度(r = 0.364,p = 0.000)以及焦虑和躯体化评分相关(r = 0.167,p = 0.015;r = 0.219,p= 0.001)。腹胀的IBS患者肌痛,抑郁和躯体化评分的患病率明显高于没有腹胀的IBS患者。

结论
IBS腹胀的症状和疼痛严重程度与患者是否抑郁,纤维肌痛和饮食液体成分改变有关。

原始出处:

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    2019-06-12 qindq
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